{"id":"https://openalex.org/W2028081804","doi":"https://doi.org/10.1016/s0040-4020(98)00845-x","title":"Functionalization of a non activated CH bond: Fluorination of vindoline at C-20 in superacids","display_name":"Functionalization of a non activated CH bond: Fluorination of vindoline at C-20 in superacids","publication_year":1998,"publication_date":"1998-11-01","ids":{"openalex":"https://openalex.org/W2028081804","doi":"https://doi.org/10.1016/s0040-4020(98)00845-x","mag":"2028081804"},"language":"en","primary_location":{"id":"doi:10.1016/s0040-4020(98)00845-x","doi":"https://doi.org/10.1016/s0040-4020(98)00845-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4020(98)00845-x","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068129308","display_name":"CHRISTIAN BERRIER","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christian Berrier","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111777419","display_name":"Jean\u2010Claude Jacquesy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Claude Jacquesy","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033618533","display_name":"Marie\u2010Paule Jouannetaud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Paule Jouannetaud","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082435066","display_name":"C\u00e9cile Lafitte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ce\u00b4cile Lafitte","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065933262","display_name":"Yves Vidal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yves Vidal","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111989642","display_name":"Fabien Zunino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210087837","display_name":"Institut de Chimie des Milieux et des Mat\u00e9riaux de Poitiers","ror":"https://ror.org/001n7ee52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I32881790","https://openalex.org/I4210087837","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fabien Zunino","raw_affiliation_strings":["Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Synthe`se et Re\u00b4activite\u00b4des Substances Naturelles, UMR 6514 Universite\u00b4de Poitiers, 86022-Poitiers, France","institution_ids":["https://openalex.org/I32881790","https://openalex.org/I4210087837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036878995","display_name":"Jacques Fahy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143394","display_name":"Pierre Fabre (France)","ror":"https://ror.org/04hdhz511","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210143394"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jacques Fahy","raw_affiliation_strings":["Division de Chimie Me\u00b4dicinale V, Centre de Recherche Pierre Fabre, 81106-Castres, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division de Chimie Me\u00b4dicinale V, Centre de Recherche Pierre Fabre, 81106-Castres, France","institution_ids":["https://openalex.org/I4210143394"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060205788","display_name":"Alain Duflos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143394","display_name":"Pierre Fabre (France)","ror":"https://ror.org/04hdhz511","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210143394"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alain Duflos","raw_affiliation_strings":["Division de Chimie Me\u00b4dicinale V, Centre de Recherche Pierre Fabre, 81106-Castres, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division de Chimie Me\u00b4dicinale V, Centre de Recherche Pierre Fabre, 81106-Castres, France","institution_ids":["https://openalex.org/I4210143394"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":0.4607,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.54547248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"54","issue":"45","first_page":"13761","last_page":"13770"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14068","display_name":"Organic and Inorganic Chemical Reactions","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14068","display_name":"Organic and Inorganic Chemical Reactions","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10947","display_name":"Fluorine in Organic Chemistry","score":0.024900000542402267,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12191","display_name":"Chemical Reaction Mechanisms","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vindoline","display_name":"vindoline","score":0.9909999966621399},{"id":"https://openalex.org/keywords/superacids","display_name":"superacids","score":0.8840000033378601},{"id":"https://openalex.org/keywords/hf-sbf5","display_name":"HF/SbF5","score":0.8330000042915344},{"id":"https://openalex.org/keywords/n-bromosuccinimide","display_name":"N-bromosuccinimide","score":0.8759999871253967},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"hydrogen peroxide","score":0.9520000219345093},{"id":"https://openalex.org/keywords/onium-ions","display_name":"onium ions","score":0.7179999947547913},{"id":"https://openalex.org/keywords/1-3-hydride-shift","display_name":"1,3-hydride shift","score":0.9900000095367432},{"id":"https://openalex.org/keywords/electrophilic-substitution","display_name":"electrophilic substitution","score":0.5709999799728394}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9685304164886475},{"id":"https://openalex.org/C50027330","wikidata":"https://www.wikidata.org/wiki/Q908086","display_name":"Electrophile","level":3,"score":0.8451041579246521},{"id":"https://openalex.org/C2777621752","wikidata":"https://www.wikidata.org/wiki/Q15427936","display_name":"Vindoline","level":4,"score":0.7909131646156311},{"id":"https://openalex.org/C2777961443","wikidata":"https://www.wikidata.org/wiki/Q106520","display_name":"Hydride","level":3,"score":0.7029509544372559},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.6546746492385864},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.5527973771095276},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.4983048439025879},{"id":"https://openalex.org/C68381374","wikidata":"https://www.wikidata.org/wiki/Q258652","display_name":"Double bond","level":2,"score":0.4268604815006256},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2860315442085266},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.1424972414970398},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.07389611005783081},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.07030093669891357},{"id":"https://openalex.org/C2777132456","wikidata":"https://www.wikidata.org/wiki/Q282629","display_name":"Vinblastine","level":3,"score":0.0},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0040-4020(98)00845-x","doi":"https://doi.org/10.1016/s0040-4020(98)00845-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4020(98)00845-x","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1555195381","https://openalex.org/W1981091459","https://openalex.org/W1993050347","https://openalex.org/W2001110558","https://openalex.org/W2020922048","https://openalex.org/W2021578778","https://openalex.org/W2063606847","https://openalex.org/W2076266168","https://openalex.org/W2080914835","https://openalex.org/W2087533253","https://openalex.org/W2322012902","https://openalex.org/W4250563967"],"related_works":["https://openalex.org/W1987227665","https://openalex.org/W2949102136","https://openalex.org/W2038550600","https://openalex.org/W2952907710","https://openalex.org/W3012987875","https://openalex.org/W2800951369","https://openalex.org/W1995714552","https://openalex.org/W2080914835","https://openalex.org/W2109521556","https://openalex.org/W2168441318"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}