{"id":"https://openalex.org/W2027411808","doi":"https://doi.org/10.1067/mob.2000.108081","title":"Continuous combined hormone replacement therapy and risk of endometrial cancer","display_name":"Continuous combined hormone replacement therapy and risk of endometrial cancer","publication_year":2000,"publication_date":"2000-12-01","ids":{"openalex":"https://openalex.org/W2027411808","doi":"https://doi.org/10.1067/mob.2000.108081","mag":"2027411808","pmid":"https://pubmed.ncbi.nlm.nih.gov/11120510"},"language":"en","primary_location":{"id":"doi:10.1067/mob.2000.108081","doi":"https://doi.org/10.1067/mob.2000.108081","is_oa":false,"landing_page_url":"https://doi.org/10.1067/mob.2000.108081","pdf_url":null,"source":{"id":"https://openalex.org/S122347013","display_name":"American Journal of Obstetrics and Gynecology","issn_l":"0002-9378","issn":["0002-9378","1085-8709","1097-6868"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Obstetrics and Gynecology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014969556","display_name":"Deirdre A. Hill","orcid":"https://orcid.org/0000-0002-8495-659X","observed_orcids":["https://orcid.org/0000-0002-8495-659X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deirdre A. Hill","raw_affiliation_strings":["Department of Epidemiology, University of Washington, Seattle, WA, USA","Department of Epidemiology Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Epidemiology Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016958524","display_name":"Noel S. Weiss","orcid":"https://orcid.org/0000-0002-3987-5184","observed_orcids":["https://orcid.org/0000-0002-3987-5184"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noel S. Weiss","raw_affiliation_strings":["Department of Epidemiology Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069321664","display_name":"Shirley A.A. Beresford","orcid":"https://orcid.org/0000-0002-1631-3541","observed_orcids":["https://orcid.org/0000-0002-1631-3541"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shirley A.A. Beresford","raw_affiliation_strings":["Department of Epidemiology Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109289848","display_name":"Lynda F. Voigt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynda F. Voigt","raw_affiliation_strings":["University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111802584","display_name":"Janet R. Daling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet R. Daling","raw_affiliation_strings":["Department of Epidemiology Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054491363","display_name":"Janet L. Stanford","orcid":"https://orcid.org/0000-0001-5062-4784","observed_orcids":["https://orcid.org/0000-0001-5062-4784"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet L. Stanford","raw_affiliation_strings":["Department of Epidemiology Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052944725","display_name":"Steve G Self","orcid":"https://orcid.org/0000-0002-0480-3340","observed_orcids":["https://orcid.org/0000-0002-0480-3340"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve Self","raw_affiliation_strings":["Department of Biostatistics Seattle, Washington","University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"University of Washington, and the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center. Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210089486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5410,"currency":"USD","value_usd":5410},"apc_paid":null,"fwci":5.4777,"has_fulltext":false,"cited_by_count":93,"citation_normalized_percentile":{"value":0.96232928,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"183","issue":"6","first_page":"1456","last_page":"1461"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endometrial-cancer","display_name":"endometrial cancer","score":0.8830000162124634},{"id":"https://openalex.org/keywords/continuous-combined-hormone-replacement-therapy","display_name":"continuous combined hormone replacement therapy","score":0.9570000171661377},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.5920000076293945},{"id":"https://openalex.org/keywords/progestogens","display_name":"progestogens","score":0.9940000176429749},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.9049999713897705},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.7929999828338623},{"id":"https://openalex.org/keywords/hormone-therapy-duration","display_name":"duration of hormone therapy","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8779199719429016},{"id":"https://openalex.org/C2780159708","wikidata":"https://www.wikidata.org/wiki/Q17003363","display_name":"Hormone replacement therapy (female-to-male)","level":3,"score":0.8137657642364502},{"id":"https://openalex.org/C2777088508","wikidata":"https://www.wikidata.org/wiki/Q944777","display_name":"Endometrial cancer","level":3,"score":0.6962720155715942},{"id":"https://openalex.org/C2780572241","wikidata":"https://www.wikidata.org/wiki/Q45071","display_name":"Progestogen","level":3,"score":0.5741965770721436},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.5547081828117371},{"id":"https://openalex.org/C2780275930","wikidata":"https://www.wikidata.org/wiki/Q1628266","display_name":"Hormone therapy","level":4,"score":0.5510155558586121},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5355252027511597},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.44480499625205994},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.42773938179016113},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.42323315143585205},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.38328418135643005},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3755241930484772},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3532048761844635},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.08835497498512268},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011372","descriptor_name":"Progestins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011372","descriptor_name":"Progestins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D011372","descriptor_name":"Progestins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016889","descriptor_name":"Endometrial Neoplasms","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D020249","descriptor_name":"Hormone Replacement Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1067/mob.2000.108081","doi":"https://doi.org/10.1067/mob.2000.108081","is_oa":false,"landing_page_url":"https://doi.org/10.1067/mob.2000.108081","pdf_url":null,"source":{"id":"https://openalex.org/S122347013","display_name":"American Journal of Obstetrics and Gynecology","issn_l":"0002-9378","issn":["0002-9378","1085-8709","1097-6868"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Obstetrics and Gynecology","raw_type":"journal-article"},{"id":"pmid:11120510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11120510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of obstetrics and gynecology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G218073325","display_name":"SURVEILLANCE EPIDEMIOLOGY AND END RESULTS","funder_award_id":"n01cn005230-022","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5393359367","display_name":null,"funder_award_id":"R01-CA-39779","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G756185268","display_name":null,"funder_award_id":"N01CN05230","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8965745508","display_name":"RESEARCH IN CANCER EPIDEMIOLOGY","funder_award_id":"R35CA039779","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W125936910","https://openalex.org/W1452220229","https://openalex.org/W1514585428","https://openalex.org/W2003202094","https://openalex.org/W2016677964","https://openalex.org/W2035593552","https://openalex.org/W2036044692","https://openalex.org/W2046983302","https://openalex.org/W2048828870","https://openalex.org/W2050108803","https://openalex.org/W2061154610","https://openalex.org/W2069883047","https://openalex.org/W2076350025","https://openalex.org/W2079450135","https://openalex.org/W2111453130","https://openalex.org/W2113264115","https://openalex.org/W2126845172","https://openalex.org/W2159416286","https://openalex.org/W2172094497","https://openalex.org/W2255952343","https://openalex.org/W2271397059","https://openalex.org/W2285162454","https://openalex.org/W2333702587","https://openalex.org/W2335854637","https://openalex.org/W2398791653","https://openalex.org/W4252441311"],"related_works":["https://openalex.org/W1973078359","https://openalex.org/W4296946107","https://openalex.org/W1991296863","https://openalex.org/W2196356438","https://openalex.org/W2171549085","https://openalex.org/W2126845172","https://openalex.org/W2084712334","https://openalex.org/W4248512899","https://openalex.org/W2159416286","https://openalex.org/W7096143725"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}