{"id":"https://openalex.org/W2026437336","doi":"https://doi.org/10.1016/0022-3956(93)90023-u","title":"Maintenance drug therapy of panic disorder","display_name":"Maintenance drug therapy of panic disorder","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2026437336","doi":"https://doi.org/10.1016/0022-3956(93)90023-u","mag":"2026437336","pmid":"https://pubmed.ncbi.nlm.nih.gov/8145175"},"language":"en","primary_location":{"id":"doi:10.1016/0022-3956(93)90023-u","doi":"https://doi.org/10.1016/0022-3956(93)90023-u","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-3956(93)90023-u","pdf_url":null,"source":{"id":"https://openalex.org/S160879026","display_name":"Journal of Psychiatric Research","issn_l":"0022-3956","issn":["0022-3956","1879-1379"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychiatric Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112600336","display_name":"George C. Curtis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"George C. Curtis","raw_affiliation_strings":["University of Michigan, Ann Arbor","University of Michigan, Department of Psychiatry, Med Inn Bldg 444, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0840, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan, Ann Arbor","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"University of Michigan, Department of Psychiatry, Med Inn Bldg 444, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0840, U.S.A","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111706605","display_name":"J. Massana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan Massana","raw_affiliation_strings":["University of Michigan, Department of Psychiatry, Med Inn Bldg 444, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0840, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan, Department of Psychiatry, Med Inn Bldg 444, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0840, U.S.A","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038130017","display_name":"Claudi Udina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Claudio Udina","raw_affiliation_strings":["University of Barcelona, Spain","Univ of Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]},{"raw_affiliation_string":"Univ of Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078407476","display_name":"Jos\u00e9 Luis Ayuso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jose Luis Ayuso","raw_affiliation_strings":["Complutense University, Madrid, Spain","Complutense Univ, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Complutense University, Madrid, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"Complutense Univ, Madrid, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052916622","display_name":"Giovanni Battista Cassano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni B. Cassano","raw_affiliation_strings":["Universita Degli Studi di Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universita Degli Studi di Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014951763","display_name":"Giulio Perugi","orcid":"https://orcid.org/0000-0001-5556-1858","observed_orcids":["https://orcid.org/0000-0001-5556-1858"]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giulio Perugi","raw_affiliation_strings":["Universita Degli Studi di Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universita Degli Studi di Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5112600336"],"corresponding_institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210114445"],"apc_list":{"value":3320,"currency":"USD","value_usd":3320},"apc_paid":null,"fwci":0.8277,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.72294275,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"27","issue":null,"first_page":"127","last_page":"142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13118","display_name":"Psychological Treatments and Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":0.9940000176429749},{"id":"https://openalex.org/keywords/agoraphobia","display_name":"agoraphobia","score":0.8600000143051147},{"id":"https://openalex.org/keywords/maintenance-therapy","display_name":"maintenance therapy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/alprazolam","display_name":"alprazolam","score":0.9649999737739563},{"id":"https://openalex.org/keywords/imipramine","display_name":"imipramine","score":0.9850000143051147},{"id":"https://openalex.org/keywords/benzodiazepines","display_name":"benzodiazepines","score":0.9330000281333923},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9940000176429749},{"id":"https://openalex.org/keywords/long-term-efficacy","display_name":"long-term efficacy","score":0.6909999847412109},{"id":"https://openalex.org/keywords/placebo-response","display_name":"placebo response","score":0.5559999942779541},{"id":"https://openalex.org/keywords/drug-tolerance","display_name":"drug tolerance","score":0.4860000014305115},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.7843030691146851},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6173648238182068},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.5712366700172424},{"id":"https://openalex.org/C2780712732","wikidata":"https://www.wikidata.org/wiki/Q208450","display_name":"Panic","level":3,"score":0.5117887854576111},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.45672422647476196},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.4484460949897766},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4343614876270294},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4234526753425598},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3205451965332031},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.20593002438545227}],"mesh":[{"descriptor_ui":"D000379","descriptor_name":"Agoraphobia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000379","descriptor_name":"Agoraphobia","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D000525","descriptor_name":"Alprazolam","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000525","descriptor_name":"Alprazolam","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D008134","descriptor_name":"Long-Term Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/0022-3956(93)90023-u","doi":"https://doi.org/10.1016/0022-3956(93)90023-u","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-3956(93)90023-u","pdf_url":null,"source":{"id":"https://openalex.org/S160879026","display_name":"Journal of Psychiatric Research","issn_l":"0022-3956","issn":["0022-3956","1879-1379"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychiatric Research","raw_type":"journal-article"},{"id":"pmid:8145175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8145175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of psychiatric research","raw_type":"Clinical Trial"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1003.5817","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1003.5817","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://deepblue.lib.umich.edu/bitstream/handle/2027.42/31052/0000729.pdf%3Bjsessionid%3D1B39EB1B12ADA858294821CA69214914?sequence%3D1","raw_type":"text"},{"id":"pmh:oai:arpi.unipi.it:11568/22432","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11568/22432","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/31052","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2027.42/31052","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W22895721","https://openalex.org/W107179074","https://openalex.org/W1890259382","https://openalex.org/W1969418247","https://openalex.org/W2021986662","https://openalex.org/W2022811258","https://openalex.org/W2035131917","https://openalex.org/W2047095780","https://openalex.org/W2049657262","https://openalex.org/W2063036729","https://openalex.org/W2063100289","https://openalex.org/W2063163312","https://openalex.org/W2068629053","https://openalex.org/W2091044346","https://openalex.org/W2160493677","https://openalex.org/W2404183638","https://openalex.org/W2406451703","https://openalex.org/W2409736578","https://openalex.org/W2410107316","https://openalex.org/W2413538559","https://openalex.org/W2416559970","https://openalex.org/W2417758972","https://openalex.org/W2432230000","https://openalex.org/W2461403361","https://openalex.org/W2781790481"],"related_works":["https://openalex.org/W7095682672","https://openalex.org/W2019194252","https://openalex.org/W2009773419","https://openalex.org/W2029368219","https://openalex.org/W2068746830","https://openalex.org/W2046840283","https://openalex.org/W2432230000","https://openalex.org/W2411224290","https://openalex.org/W2016847652","https://openalex.org/W1988522912"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}