{"id":"https://openalex.org/W2026219005","doi":"https://doi.org/10.2307/3577002","title":"Comparison of Intestine and Bone Marrow Radiosensitivity of the BALB/c and the C57BL/6 Mouse Strains and Their B6CF 1 Offspring","display_name":"Comparison of Intestine and Bone Marrow Radiosensitivity of the BALB/c and the C57BL/6 Mouse Strains and Their B6CF 1 Offspring","publication_year":1987,"publication_date":"1987-06-01","ids":{"openalex":"https://openalex.org/W2026219005","doi":"https://doi.org/10.2307/3577002","mag":"2026219005","pmid":"https://pubmed.ncbi.nlm.nih.gov/3588842"},"language":"en","primary_location":{"id":"doi:10.2307/3577002","doi":"https://doi.org/10.2307/3577002","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3577002","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079936279","display_name":"W Hanson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. R. Hanson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080470127","display_name":"Richard J. Fry","orcid":"https://orcid.org/0000-0002-7968-6679","observed_orcids":["https://orcid.org/0000-0002-7968-6679"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. J. M. Fry","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070284492","display_name":"Anthony Sallese","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. R. Sallese","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036842191","display_name":"Henri Frischer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Frischer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"T. Ahmad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Ahmad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111938469","display_name":"E. John Ainsworth","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. J. Ainsworth","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5143,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.69200145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"110","issue":"3","first_page":"340","last_page":"340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiosensitivity","display_name":"radiosensitivity","score":0.8679999709129333},{"id":"https://openalex.org/keywords/mouse-strain-differences","display_name":"mouse strain differences","score":0.7059999704360962},{"id":"https://openalex.org/keywords/balb-c-mice","display_name":"BALB/c mice","score":0.9660000205039978},{"id":"https://openalex.org/keywords/c57bl-6-mice","display_name":"C57BL/6 mice","score":1.0},{"id":"https://openalex.org/keywords/bone-marrow-derived-stem-cells","display_name":"bone marrow-derived stem cells","score":0.9179999828338623},{"id":"https://openalex.org/keywords/cfu-s","display_name":"CFU-S","score":0.9610000252723694},{"id":"https://openalex.org/keywords/d0","display_name":"D0","score":0.5189999938011169},{"id":"https://openalex.org/keywords/cell-cycle-kinetics","display_name":"cell cycle kinetics","score":0.6930000185966492},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.5759999752044678},{"id":"https://openalex.org/keywords/neutron","display_name":"neutrons","score":0.5649999976158142},{"id":"https://openalex.org/keywords/gamma-radiation","display_name":"gamma radiation","score":0.7739999890327454},{"id":"https://openalex.org/keywords/mucosal-barrier","display_name":"mucosal barrier","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C206684579","wikidata":"https://www.wikidata.org/wiki/Q4387689","display_name":"Radiosensitivity","level":3,"score":0.7875025272369385},{"id":"https://openalex.org/C117262875","wikidata":"https://www.wikidata.org/wiki/Q5135057","display_name":"Clonogenic assay","level":3,"score":0.676624059677124},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5965449213981628},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5757629871368408},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5449038147926331},{"id":"https://openalex.org/C2776529007","wikidata":"https://www.wikidata.org/wiki/Q9820","display_name":"BALB/c","level":3,"score":0.5443264245986938},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5165857076644897},{"id":"https://openalex.org/C66090201","wikidata":"https://www.wikidata.org/wiki/Q15995009","display_name":"Crypt","level":2,"score":0.48727595806121826},{"id":"https://openalex.org/C2776095844","wikidata":"https://www.wikidata.org/wiki/Q903666","display_name":"Colcemid","level":3,"score":0.4755406379699707},{"id":"https://openalex.org/C2777544843","wikidata":"https://www.wikidata.org/wiki/Q21136","display_name":"Lethal dose","level":2,"score":0.44509702920913696},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3872154951095581},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.34273865818977356},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.336525022983551},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.16212335228919983},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15465494990348816},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15246576070785522},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1287926435470581},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1195572018623352},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.10140541195869446},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.06265231966972351},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D003037","descriptor_name":"Cobalt Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005720","descriptor_name":"Gamma Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006824","descriptor_name":"Hybridization, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2307/3577002","doi":"https://doi.org/10.2307/3577002","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3577002","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},{"id":"pmid:3588842","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3588842","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation research","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320338284","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W29694633","https://openalex.org/W306851750","https://openalex.org/W328387259","https://openalex.org/W1568283473","https://openalex.org/W1975805580","https://openalex.org/W2007064404","https://openalex.org/W2027063572","https://openalex.org/W2038229034","https://openalex.org/W2038555958","https://openalex.org/W2152944453","https://openalex.org/W2402823975","https://openalex.org/W2413412002","https://openalex.org/W2561898719"],"related_works":["https://openalex.org/W1558890492","https://openalex.org/W30347092","https://openalex.org/W2416688216","https://openalex.org/W1584507413","https://openalex.org/W1539866154","https://openalex.org/W3144964518","https://openalex.org/W2470650631","https://openalex.org/W41370819","https://openalex.org/W2201990748","https://openalex.org/W2330780250"],"abstract_inverted_index":{"The":[0,28,44,129,248],"radiosensitivity":[1,93],"as":[2],"measured":[3],"by":[4,63],"LD50/6":[5,29,47,82],"or":[6,52,73,244],"LD50/30":[7],"of":[8,20,94,106,122,188,225,239],"the":[9,42,49,56,77,81,92,100,103,117,136,139,144,165,177,183,207,215,218,222,226,240,258,274,277,285],"F1":[10,57],"hybrid":[11,58,260],"B6CF1":[12,162,184,219,227,259],"(C57BL/6":[13],"X":[14],"BALB/c)":[15],"is":[16],"similar":[17],"to":[18,38,86,134,196,229,279,282],"that":[19,283],"C57BL/6":[21],"mice":[22,32,107,157,179],"but":[23],"markedly":[24],"different":[25],"from":[26,88],"BALB/c.":[27,286],"for":[30,41,102,138,147,155,161,168,176,182],"BALB/c":[31,54,156,178,216,241],"was":[33,132],"about":[34,152],"8.8":[35],"Gy":[36,40,154,160,175],"compared":[37,281],"16.4":[39],"B6CF1.":[43],"difference":[45,275],"in":[46,66,80,91,116,213,252,257,271,276,284],"between":[48,53,198],"parent":[50],"strains":[51],"and":[55,143,158,180,200,217,269],"could":[59],"not":[60,84],"be":[61],"explained":[62],"any":[64],"differences":[65,79,90,115],"crypt":[67,140],"cell":[68,70,120,190,233,255],"number,":[69],"cycle":[71,234],"time,":[72],"transit":[74],"time.":[75],"Likewise,":[76],"observed":[78],"do":[83],"appear":[85,228],"result":[87],"marked":[89],"marrow":[95],"stem":[96,208,223],"cells":[97,142,203,209,224],"(CFU-S)":[98],"since":[99],"D0's":[101],"three":[104],"genotypes":[105],"were":[108,112,151,172],"similar.":[109],"Also,":[110],"there":[111],"no":[113],"apparent":[114],"red":[118],"blood":[119],"contents":[121],"several":[123],"enzymes":[124],"associated":[125],"with":[126],"antioxidant":[127],"defenses.":[128],"microcolony":[130],"assay":[131],"used":[133],"determine":[135],"D0":[137,145,166],"clonogenic":[141,189],"values":[146,167],"60Co":[148],"gamma":[149],"rays":[150],"0.8":[153],"1.4":[159],"mice.":[163,185],"However,":[164,221],"JANUS":[169],"fission":[170],"neutrons":[171],"similar;":[173],"0.6":[174],"0.5":[181],"A":[186],"comparison":[187],"kinetics,":[191],"using":[192],"prolonged":[193,245],"colcemid":[194,246],"block":[195],"distinguish":[197],"slowly":[199,211],"rapidly":[201,236],"cycling":[202,212],"suggest":[204],"that,":[205],"normally,":[206],"are":[210],"both":[214],"hybrid.":[220],"go":[230],"into":[231],"rapid":[232,250],"more":[235,249],"than":[237],"those":[238],"following":[242],"irradiation":[243,262],"treatment.":[247],"recovery":[251],"intestinal":[253],"epihelial":[254],"production":[256],"after":[261],"may":[263],"provide":[264],"an":[265],"increased":[266],"mucosal":[267],"barrier":[268],"may,":[270],"part,":[272],"explain":[273],"response":[278],"radiation":[280]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}