{"id":"https://openalex.org/W2025838532","doi":"https://doi.org/10.3171/jns.1978.49.4.0563","title":"Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma","display_name":"Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma","publication_year":1978,"publication_date":"1978-10-01","ids":{"openalex":"https://openalex.org/W2025838532","doi":"https://doi.org/10.3171/jns.1978.49.4.0563","mag":"2025838532","pmid":"https://pubmed.ncbi.nlm.nih.gov/211207"},"language":"en","primary_location":{"id":"doi:10.3171/jns.1978.49.4.0563","doi":"https://doi.org/10.3171/jns.1978.49.4.0563","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1978.49.4.0563","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035602914","display_name":"Nancy R. Clendenon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nancy R. Clendenon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113569166","display_name":"Norman Allen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Norman Allen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026778493","display_name":"Wanda A. Gordon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wanda A. Gordon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5017127723","display_name":"W. George Bingham","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. George Bingham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4269,"has_fulltext":false,"cited_by_count":110,"citation_normalized_percentile":{"value":0.87095096,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"49","issue":"4","first_page":"563","last_page":"568"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.8481000065803528,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.8481000065803528,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.08550000190734863,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.030500000342726707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.9629999995231628},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.8059999942779541},{"id":"https://openalex.org/keywords/impact-injury","display_name":"impact injury","score":0.9660000205039978},{"id":"https://openalex.org/keywords/enzyme-inhibition","display_name":"enzyme inhibition","score":0.8009999990463257},{"id":"https://openalex.org/keywords/membrane-bound-atpase","display_name":"membrane ATPase","score":0.7990000247955322},{"id":"https://openalex.org/keywords/mg2-dependent-atpase","display_name":"Mg2+-dependent ATPase","score":0.9229999780654907},{"id":"https://openalex.org/keywords/blood-flow","display_name":"blood flow","score":0.7020000219345093},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.7940000295639038},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.902999997138977},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7384485006332397},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.7190548777580261},{"id":"https://openalex.org/C3018891471","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"Adenosine triphosphatase","level":4,"score":0.6361769437789917},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.5761563777923584},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.5280141234397888},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.523494303226471},{"id":"https://openalex.org/C28212737","wikidata":"https://www.wikidata.org/wiki/Q5381543","display_name":"Enzyme assay","level":3,"score":0.4927976429462433},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48586055636405945},{"id":"https://openalex.org/C2779340330","wikidata":"https://www.wikidata.org/wiki/Q7843291","display_name":"Triphosphatase","level":3,"score":0.483083039522171},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46091535687446594},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3953145146369934},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1927105188369751},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13292288780212402},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000251","descriptor_name":"Adenosine Triphosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3171/jns.1978.49.4.0563","doi":"https://doi.org/10.3171/jns.1978.49.4.0563","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1978.49.4.0563","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:211207","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/211207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W639414218","https://openalex.org/W1586357743","https://openalex.org/W1775749144","https://openalex.org/W1971519888","https://openalex.org/W1975989619","https://openalex.org/W1976704090","https://openalex.org/W1979285801","https://openalex.org/W1990728049","https://openalex.org/W1994408334","https://openalex.org/W2015553589","https://openalex.org/W2020854479","https://openalex.org/W2034807801","https://openalex.org/W2039122331","https://openalex.org/W2047534532","https://openalex.org/W2067187143","https://openalex.org/W2069812091","https://openalex.org/W2071365883","https://openalex.org/W2086051035","https://openalex.org/W2086953796","https://openalex.org/W2107240672","https://openalex.org/W2119067747","https://openalex.org/W2128553647","https://openalex.org/W2130810272","https://openalex.org/W2143573459","https://openalex.org/W2153435210","https://openalex.org/W2170600798","https://openalex.org/W2205753780","https://openalex.org/W2255068084","https://openalex.org/W2404426883","https://openalex.org/W3165208394"],"related_works":["https://openalex.org/W2258964537","https://openalex.org/W2046813815","https://openalex.org/W2427482639","https://openalex.org/W1980586997","https://openalex.org/W2415582869","https://openalex.org/W2034694448","https://openalex.org/W2063737190","https://openalex.org/W2126994317","https://openalex.org/W2033562010","https://openalex.org/W2019984022"],"abstract_inverted_index":{"The":[0,29,135],"specific":[1],"activity":[2,39,108],"of":[3,55,71,75,97,109,127,137],"the":[4,24,58,68,72,85,91,98,107,110,122,125],"membrane-bound":[5,138],"enzyme,":[6],"Na+-K+-activated":[7,92],"adenosine":[8],"triphosphatase":[9],"(ATPase),":[10],"has":[11],"been":[12],"shown":[13],"to":[14,23,53,84,95,141],"be":[15],"decreased":[16],"following":[17],"experimental":[18],"impact":[19],"injury":[20,129],"(400":[21],"gm-cm)":[22],"spinal":[25,76],"cord":[26],"in":[27,38,67,121],"dogs.":[28],"prompt":[30],"and":[31,49,100,146],"significant":[32],"(p":[33],"less":[34],"than":[35],"0.01)":[36],"fall":[37],"was":[40,64],"evident":[41],"as":[42,44],"early":[43,132],"5":[45],"minutes":[46],"after":[47],"injury,":[48],"remained":[50],"at":[51,130],"56%":[52],"67%":[54],"control":[56,101],"for":[57,90],"1-hour":[59],"period":[60],"studied.":[61],"This":[62],"decrease":[63],"most":[65],"prominent":[66],"central":[69],"core":[70,79],"traumatized":[73],"segments":[74],"cord.":[77],"Central":[78],"samples,":[80,106],"excised":[81],"immediately":[82],"adjacent":[83],"trauma":[86,99],"site,":[87],"gave":[88],"values":[89],"enzyme":[93,139],"intermediate":[94],"those":[96],"sites.":[102],"For":[103],"these":[104,131],"same":[105],"Mg+2-dependent":[111],"ATPase":[112],"did":[113],"not":[114],"change":[115],"appreciably.":[116],"No":[117],"alterations":[118,140],"were":[119],"observed":[120],"tissue":[123],"surrounding":[124],"zone":[126],"maximum":[128],"time":[133],"periods.":[134],"relationship":[136],"blood":[142],"flow,":[143],"clotting":[144],"mechanisms,":[145],"abnormal":[147],"free":[148],"radical":[149],"reactions":[150],"are":[151],"briefly":[152],"discussed.":[153]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}