{"id":"https://openalex.org/W2025812778","doi":"https://doi.org/10.1097/00002480-200603000-00206","title":"ACUTE HEMODYNAMIC AND PRESSURE-VOLUME RESPONSES TO CONTINUOUS AND PULSATILE ASSIST IN DIMINISHED CARDIAC FUNCTION CALF MODEL","display_name":"ACUTE HEMODYNAMIC AND PRESSURE-VOLUME RESPONSES TO CONTINUOUS AND PULSATILE ASSIST IN DIMINISHED CARDIAC FUNCTION CALF MODEL","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W2025812778","doi":"https://doi.org/10.1097/00002480-200603000-00206","mag":"2025812778"},"language":"en","primary_location":{"id":"doi:10.1097/00002480-200603000-00206","doi":"https://doi.org/10.1097/00002480-200603000-00206","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002480-200603000-00206","pdf_url":null,"source":{"id":"https://openalex.org/S8999885","display_name":"ASAIO Journal","issn_l":"1058-2916","issn":["1058-2916","1538-943X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058610345","display_name":"Steven C. Koenig","orcid":"https://orcid.org/0000-0002-8348-6127","observed_orcids":["https://orcid.org/0000-0002-8348-6127"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven C Koenig","raw_affiliation_strings":["Bioengineering and Surgery, University of Louisville, Louisville, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Surgery, University of Louisville, Louisville, KY","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069633988","display_name":"Guruprasad A. Giridharan","orcid":"https://orcid.org/0000-0003-3263-9354","observed_orcids":["https://orcid.org/0000-0003-3263-9354"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guruprasad A Giridharan","raw_affiliation_strings":["Bioengineering and Surgery, University of Louisville, Louisville, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Surgery, University of Louisville, Louisville, KY","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003075623","display_name":"George M. Pantalos","orcid":"https://orcid.org/0000-0002-3553-8893","observed_orcids":["https://orcid.org/0000-0002-3553-8893"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George M Pantalos","raw_affiliation_strings":["Bioengineering and Surgery, University of Louisville, Louisville, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Surgery, University of Louisville, Louisville, KY","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026309132","display_name":"Kenneth N. Litwak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth N Litwak","raw_affiliation_strings":["Bioengineering and Surgery, University of Louisville, Louisville, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Surgery, University of Louisville, Louisville, KY","institution_ids":["https://openalex.org/I142740786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I142740786"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.17359813,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"52","issue":"2","first_page":"48A","last_page":"48A"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ventricular-assist-devices","display_name":"ventricular assist devices","score":0.9700000286102295},{"id":"https://openalex.org/keywords/continuous-flow-ventricular-assist","display_name":"continuous-flow ventricular assist","score":0.8479999899864197},{"id":"https://openalex.org/keywords/left-ventricular-pressure-volume-relationship","display_name":"left ventricular pressure-volume relationship","score":0.7509999871253967},{"id":"https://openalex.org/keywords/hemodynamic-response","display_name":"hemodynamic response","score":0.6029999852180481},{"id":"https://openalex.org/keywords/coronary-blood-flow","display_name":"coronary blood flow","score":0.46700000762939453},{"id":"https://openalex.org/keywords/left-ventricular-end-systolic-volume","display_name":"left ventricular end-systolic volume","score":0.6759999990463257},{"id":"https://openalex.org/keywords/calves","display_name":"calves","score":0.3880000114440918},{"id":"https://openalex.org/keywords/cardiac-recovery","display_name":"cardiac function recovery","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.7406216263771057},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7201778292655945},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6828065514564514},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6685335636138916},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.607993483543396},{"id":"https://openalex.org/C39124391","wikidata":"https://www.wikidata.org/wiki/Q4778759","display_name":"Aortic pressure","level":3,"score":0.5113248229026794},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.5038191676139832},{"id":"https://openalex.org/C2778774980","wikidata":"https://www.wikidata.org/wiki/Q2897721","display_name":"Ventricular assist device","level":3,"score":0.45356225967407227},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.420221745967865},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.4161509573459625},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3670518100261688},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.1244388222694397}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00002480-200603000-00206","doi":"https://doi.org/10.1097/00002480-200603000-00206","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002480-200603000-00206","pdf_url":null,"source":{"id":"https://openalex.org/S8999885","display_name":"ASAIO Journal","issn_l":"1058-2916","issn":["1058-2916","1538-943X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1994286035","https://openalex.org/W2091713284","https://openalex.org/W2028297823","https://openalex.org/W2074532022","https://openalex.org/W2588397026","https://openalex.org/W2311401489","https://openalex.org/W2046399169","https://openalex.org/W2081913215","https://openalex.org/W2593249081","https://openalex.org/W2048679907"],"abstract_inverted_index":{"Acute":[0],"hemodynamic":[1],"and":[2,11,22,50,65,73,93,96,103,108,116,119,149,160,188,217,224,226,236],"left":[3,89,121],"ventricular":[4,15,71,90,122,215],"pressure-volume":[5],"responses":[6],"to":[7,175,207],"continuous":[8],"flow":[9,13,25,105],"(CF)":[10],"pulsatile":[12],"(PF)":[14],"assist":[16],"devices":[17],"(VAD)":[18],"at":[19],"50%,":[20],"75%,":[21],"100%":[23],"bypass":[24],"rates":[26],"were":[27,68,77],"investigated":[28],"in":[29,158,205,212],"calves":[30],"(n=8)":[31],"with":[32,79,124,135,168,200],"diminished":[33],"cardiac":[34,112],"function":[35],"(DCF).":[36],"A":[37],"clinically":[38],"relevant":[39],"DCF":[40],"model":[41],"(MAP":[42],"=":[43,47,52],"65\u201375":[44],"mmHg,":[45],"CO":[46],"6\u20138":[48],"L/m,":[49],"LAP":[51],"12\u201315":[53],"mmHg)":[54],"was":[55,203],"induced":[56],"by":[57],"a":[58,180],"single":[59],"oral":[60],"dose":[61],"of":[62,84,127,138,171,196,228],"Monensin.":[63],"CF":[64,109,130,148,165,186,208],"PF":[66,107,141,150,176,189,201],"VAD":[67,104,110,128,131,142,151,172,177,187,190,202,221,229],"implanted":[69],"via":[70],"apical":[72],"brachiocephallic":[74,98],"cannulae.":[75],"Calves":[76],"instrumented":[78],"catheters":[80],"for":[81,164,239],"simultaneous":[82],"measurement":[83],"aortic":[85],"root":[86],"pressure":[87,91],"(AoP),":[88],"(LVP)":[92],"volume":[94,162],"(LVV),":[95],"aortic,":[97],"artery,":[99],"coronary":[100],"artery":[101],"(CoF),":[102],"probes.":[106],"increased":[111,191],"output,":[113],"mean":[114,117],"AoP,":[115],"CoF":[118,199],"reduced":[120,152],"work":[123],"increasing":[125,136,169],"levels":[126,137,170],"support.":[129],"decreased":[132],"AoP":[133],"pulsatility":[134],"support":[139,173,230],"while":[140],"maintained":[143],"physiologic":[144,182],"pulsatility.":[145],"Although":[146],"both":[147,185],"LVV":[153],"toward":[154],"normal,":[155],"the":[156,194,197,237],"variation":[157],"end-systolic":[159],"end-diastolic":[161],"(\u0394V)":[163],"is":[166],"less":[167],"compared":[174],"which":[178],"maintains":[179],"normal":[181],"\u0394V.":[183],"Though":[184],"diastolic":[192,198],"CoF,":[193],"augmentation":[195],"higher":[204],"comparison":[206],"VAD.":[209],"The":[210],"differences":[211],"vascular":[213],"pulsatility,":[214],"volume,":[216],"myocardial":[218,240],"perfusion":[219],"between":[220],"type":[222],"(CF":[223],"PF)":[225],"level":[227],"may":[231],"impact":[232],"device":[233],"selection,":[234],"operation,":[235],"potential":[238],"recovery.":[241]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}