{"id":"https://openalex.org/W2024601575","doi":"https://doi.org/10.1021/nl052024f","title":"Vacancy Engineered Ceria Nanostructures for Protection from Radiation-Induced Cellular Damage","display_name":"Vacancy Engineered Ceria Nanostructures for Protection from Radiation-Induced Cellular Damage","publication_year":2005,"publication_date":"2005-11-25","ids":{"openalex":"https://openalex.org/W2024601575","doi":"https://doi.org/10.1021/nl052024f","mag":"2024601575","pmid":"https://pubmed.ncbi.nlm.nih.gov/16351218"},"language":"en","primary_location":{"id":"doi:10.1021/nl052024f","doi":"https://doi.org/10.1021/nl052024f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/nl052024f","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://stars.library.ucf.edu/facultybib2000/5715","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030595919","display_name":"Roy W Tarnuzzer","orcid":"https://orcid.org/0000-0002-3725-4173","observed_orcids":["https://orcid.org/0000-0002-3725-4173"]},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Roy W. Tarnuzzer","raw_affiliation_strings":["M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112169511","display_name":"Jimmie F. Colon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jimmie Colon","raw_affiliation_strings":["M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110226611","display_name":"Swanand D. Patil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Swanand Patil","raw_affiliation_strings":["M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026168431","display_name":"Sudipta Seal","orcid":"https://orcid.org/0000-0002-0963-3344","observed_orcids":["https://orcid.org/0000-0002-0963-3344"]},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sudipta Seal","raw_affiliation_strings":["M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M. D. Anderson Cancer Center Orlando, Orlando Regional Healthcare, Orlando, Florida 32806, and Burnett College of Biomedical Sciences and Advanced Materials Processing and Analysis Center, Mechanical, Materials and Aerospace Engineering, and Nanoscience and Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816","institution_ids":["https://openalex.org/I106165777"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030595919"],"corresponding_institution_ids":["https://openalex.org/I106165777"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":7.5392,"has_fulltext":false,"cited_by_count":813,"citation_normalized_percentile":{"value":0.97718547,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"5","issue":"12","first_page":"2573","last_page":"2577"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.15919999778270721,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerium-oxide-nanoparticles","display_name":"cerium oxide nanoparticles","score":0.9710000157356262},{"id":"https://openalex.org/keywords/radiation-protection","display_name":"radiation protection","score":0.8479999899864197},{"id":"https://openalex.org/keywords/radiation-induced-cell-death","display_name":"radiation-induced cell death","score":0.8450000286102295},{"id":"https://openalex.org/keywords/vacancy-engineering","display_name":"vacancy engineering","score":0.5130000114440918},{"id":"https://openalex.org/keywords/breast-cancer-cells","display_name":"breast cancer cells","score":0.7889999747276306},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.8209999799728394},{"id":"https://openalex.org/keywords/cell-survival","display_name":"cell survival","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C2780657402","wikidata":"https://www.wikidata.org/wiki/Q1055570","display_name":"Cerium oxide","level":3,"score":0.6633719205856323},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.6479998826980591},{"id":"https://openalex.org/C2994423619","wikidata":"https://www.wikidata.org/wiki/Q9103","display_name":"Human breast","level":4,"score":0.6065344214439392},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.5425925254821777},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.488338440656662},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4816816747188568},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.48136478662490845},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.48095741868019104},{"id":"https://openalex.org/C153428861","wikidata":"https://www.wikidata.org/wiki/Q152749","display_name":"Radiation damage","level":3,"score":0.4584789276123047},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.43891483545303345},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.36569467186927795},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3430917263031006},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.24458512663841248},{"id":"https://openalex.org/C2779851234","wikidata":"https://www.wikidata.org/wiki/Q50690","display_name":"Oxide","level":2,"score":0.24350276589393616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18202674388885498},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.13043904304504395},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11501336097717285},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.11470896005630493},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08517712354660034},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.05938541889190674},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001698","descriptor_name":"Biomedical Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002563","descriptor_name":"Cerium","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002563","descriptor_name":"Cerium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004304","descriptor_name":"Dosage Forms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011829","descriptor_name":"Radiation Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011835","descriptor_name":"Radiation Protection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1021/nl052024f","doi":"https://doi.org/10.1021/nl052024f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/nl052024f","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},{"id":"pmid:16351218","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16351218","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano letters","raw_type":"Journal Article"},{"id":"pmh:oai:stars.library.ucf.edu:facultybib2000-6714","doi":null,"is_oa":true,"landing_page_url":"https://stars.library.ucf.edu/facultybib2000/5715","pdf_url":null,"source":{"id":"https://openalex.org/S4210172555","display_name":"Journal of International Crisis and Risk Communication Research","issn_l":"2576-0017","issn":["2576-0017","2576-0025"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Bibliography 2000s","raw_type":"text"},{"id":"pmh:oai:stars.library.ucf.edu:scopus2000-5416","doi":null,"is_oa":true,"landing_page_url":"https://stars.library.ucf.edu/scopus2000/4417","pdf_url":null,"source":{"id":"https://openalex.org/S4210172555","display_name":"Journal of International Crisis and Risk Communication Research","issn_l":"2576-0017","issn":["2576-0017","2576-0025"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus Export 2000s","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:stars.library.ucf.edu:facultybib2000-6714","doi":null,"is_oa":true,"landing_page_url":"https://stars.library.ucf.edu/facultybib2000/5715","pdf_url":null,"source":{"id":"https://openalex.org/S4210172555","display_name":"Journal of International Crisis and Risk Communication Research","issn_l":"2576-0017","issn":["2576-0017","2576-0025"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Bibliography 2000s","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W94764885","https://openalex.org/W273581702","https://openalex.org/W1963559493","https://openalex.org/W1968367833","https://openalex.org/W1971273014","https://openalex.org/W1995036089","https://openalex.org/W2006736962","https://openalex.org/W2009614945","https://openalex.org/W2023271282","https://openalex.org/W2039962507","https://openalex.org/W2056473947","https://openalex.org/W2076989168","https://openalex.org/W2079171058","https://openalex.org/W2084188360","https://openalex.org/W2170124346","https://openalex.org/W2498731884"],"related_works":["https://openalex.org/W2764332897","https://openalex.org/W3024863562","https://openalex.org/W2889976671","https://openalex.org/W2066929065","https://openalex.org/W6964015563","https://openalex.org/W2392325026","https://openalex.org/W2519678333","https://openalex.org/W801380173","https://openalex.org/W2809644760","https://openalex.org/W3212867250"],"abstract_inverted_index":{"The":[0],"ability":[1],"of":[2,29,48],"engineered":[3],"cerium":[4],"oxide":[5],"nanoparticles":[6],"to":[7,58,61,69],"confer":[8,59],"radioprotection":[9,60],"was":[10,26],"examined.":[11],"Human":[12],"normal":[13,30,63],"and":[14,21,23],"tumor":[15,49,73],"cells":[16,31],"were":[17],"treated":[18],"with":[19],"nanoceria":[20,55],"irradiated,":[22],"cell":[24,38],"survival":[25],"measured.":[27],"Treatment":[28],"conferred":[32],"almost":[33,45],"99%":[34],"protection":[35,47],"from":[36],"radiation-induced":[37],"death,":[39],"whereas":[40],"the":[41,52],"same":[42],"concentration":[43],"showed":[44],"no":[46],"cells.":[50],"For":[51],"first":[53],"time,":[54],"is":[56],"shown":[57],"a":[62,70],"human":[64,71],"breast":[65,72],"line":[66],"but":[67],"not":[68],"line,":[74],"MCF-7.":[75]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":49},{"year":2022,"cited_by_count":45},{"year":2021,"cited_by_count":61},{"year":2020,"cited_by_count":45},{"year":2019,"cited_by_count":62},{"year":2018,"cited_by_count":74},{"year":2017,"cited_by_count":50},{"year":2016,"cited_by_count":55},{"year":2015,"cited_by_count":47},{"year":2014,"cited_by_count":48},{"year":2013,"cited_by_count":52},{"year":2012,"cited_by_count":47}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}