{"id":"https://openalex.org/W2024349232","doi":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","title":"Associations of early age\u2010related macular degeneration with ocular and general parameters. The central India eyes and medical study","display_name":"Associations of early age\u2010related macular degeneration with ocular and general parameters. The central India eyes and medical study","publication_year":2012,"publication_date":"2012-01-23","ids":{"openalex":"https://openalex.org/W2024349232","doi":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","mag":"2024349232","pmid":"https://pubmed.ncbi.nlm.nih.gov/22269029"},"language":"en","primary_location":{"id":"doi:10.1111/j.1755-3768.2011.02316.x","doi":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","pdf_url":null,"source":{"id":"https://openalex.org/S21165490","display_name":"Acta Ophthalmologica","issn_l":"0001-639X","issn":["0001-639X","1755-375X","1755-3768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Ophthalmologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082561940","display_name":"Jost Bruno Jonas","orcid":"https://orcid.org/0000-0003-2972-5227","observed_orcids":["https://orcid.org/0000-0003-2972-5227"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210164344","display_name":"Suraj Eye Institute","ror":"https://ror.org/05dd1kk08","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210164344"]},{"id":"https://openalex.org/I4387153978","display_name":"Medizinische Fakult\u00e4t Mannheim","ror":"https://ror.org/02m1z0a87","country_code":"DE","type":"education","lineage":["https://openalex.org/I4387153978"]}],"countries":["DE","IN"],"is_corresponding":false,"raw_author_name":"Jost B. Jonas","raw_affiliation_strings":["Suraj Eye Institute, Nagpur, Maharashtra, India","Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany","The first two authors contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suraj Eye Institute, Nagpur, Maharashtra, India","institution_ids":["https://openalex.org/I4210164344"]},{"raw_affiliation_string":"Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4387153978"]},{"raw_affiliation_string":"The first two authors contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101747164","display_name":"Vinay B. Nangia","orcid":"https://orcid.org/0000-0001-6143-9760","observed_orcids":["https://orcid.org/0000-0001-6143-9760"]},"institutions":[{"id":"https://openalex.org/I4210164344","display_name":"Suraj Eye Institute","ror":"https://ror.org/05dd1kk08","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210164344"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Vinay Nangia","raw_affiliation_strings":["Suraj Eye Institute, Nagpur, Maharashtra, India","The first two authors contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suraj Eye Institute, Nagpur, Maharashtra, India","institution_ids":["https://openalex.org/I4210164344"]},{"raw_affiliation_string":"The first two authors contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110242357","display_name":"Maithili Kulkarni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164344","display_name":"Suraj Eye Institute","ror":"https://ror.org/05dd1kk08","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210164344"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Maithili Kulkarni","raw_affiliation_strings":["Suraj Eye Institute, Nagpur, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suraj Eye Institute, Nagpur, Maharashtra, India","institution_ids":["https://openalex.org/I4210164344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101799527","display_name":"Rajesh Kumar Gupta","orcid":"https://orcid.org/0000-0002-4959-5477","observed_orcids":["https://orcid.org/0000-0002-4959-5477"]},"institutions":[{"id":"https://openalex.org/I4210164344","display_name":"Suraj Eye Institute","ror":"https://ror.org/05dd1kk08","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210164344"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rajesh Gupta","raw_affiliation_strings":["Suraj Eye Institute, Nagpur, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suraj Eye Institute, Nagpur, Maharashtra, India","institution_ids":["https://openalex.org/I4210164344"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038338668","display_name":"Anshu Khare","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164344","display_name":"Suraj Eye Institute","ror":"https://ror.org/05dd1kk08","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210164344"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anshu Khare","raw_affiliation_strings":["Suraj Eye Institute, Nagpur, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suraj Eye Institute, Nagpur, Maharashtra, India","institution_ids":["https://openalex.org/I4210164344"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101747164"],"corresponding_institution_ids":["https://openalex.org/I4210164344"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":4.2345,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.937433,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"90","issue":"3","first_page":"e185","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/age-related-macular-degeneration","display_name":"age-related macular degeneration","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hyperopia","display_name":"hyperopia","score":0.8149999976158142},{"id":"https://openalex.org/keywords/axial-length","display_name":"axial length","score":0.8669999837875366},{"id":"https://openalex.org/keywords/corneal-power","display_name":"corneal power","score":0.9449999928474426},{"id":"https://openalex.org/keywords/amd-risk-factors","display_name":"AMD risk factors","score":0.6850000023841858},{"id":"https://openalex.org/keywords/fruit-intake","display_name":"fruit consumption","score":0.5870000123977661},{"id":"https://openalex.org/keywords/indian-adults","display_name":"Indian adults","score":0.47600001096725464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8617758750915527},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.7260651588439941},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7163131237030029},{"id":"https://openalex.org/C2781135284","wikidata":"https://www.wikidata.org/wiki/Q470427","display_name":"Refractive error","level":3,"score":0.6069899797439575},{"id":"https://openalex.org/C169126688","wikidata":"https://www.wikidata.org/wiki/Q1310580","display_name":"Emmetropia","level":4,"score":0.5549154281616211},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5484174489974976},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.533755362033844},{"id":"https://openalex.org/C259533","wikidata":"https://www.wikidata.org/wiki/Q193933","display_name":"Dioptre","level":3,"score":0.5177544951438904},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.4729841947555542},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.4535341262817383},{"id":"https://openalex.org/C2781116099","wikidata":"https://www.wikidata.org/wiki/Q3842207","display_name":"Maculopathy","level":4,"score":0.43236973881721497},{"id":"https://openalex.org/C2776474195","wikidata":"https://www.wikidata.org/wiki/Q1144413","display_name":"Fundus photography","level":4,"score":0.41118913888931274},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.4105462431907654},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.3046233654022217},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.2836172580718994},{"id":"https://openalex.org/C2778313320","wikidata":"https://www.wikidata.org/wiki/Q550455","display_name":"Retinopathy","level":3,"score":0.2495449185371399},{"id":"https://openalex.org/C2778257484","wikidata":"https://www.wikidata.org/wiki/Q555066","display_name":"Visual acuity","level":2,"score":0.23332160711288452},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1780884861946106},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.17609652876853943},{"id":"https://openalex.org/C2780248432","wikidata":"https://www.wikidata.org/wiki/Q1434206","display_name":"Fluorescein angiography","level":3,"score":0.11672946810722351},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006956","descriptor_name":"Hyperopia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012424","descriptor_name":"Rural Population","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058452","descriptor_name":"Axial Length, Eye","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1755-3768.2011.02316.x","doi":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1755-3768.2011.02316.x","pdf_url":null,"source":{"id":"https://openalex.org/S21165490","display_name":"Acta Ophthalmologica","issn_l":"0001-639X","issn":["0001-639X","1755-375X","1755-3768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Ophthalmologica","raw_type":"journal-article"},{"id":"pmid:22269029","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22269029","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta ophthalmologica","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W187723863","https://openalex.org/W1469632344","https://openalex.org/W1492028104","https://openalex.org/W1520662388","https://openalex.org/W1536779003","https://openalex.org/W1565600091","https://openalex.org/W1597408111","https://openalex.org/W1974172116","https://openalex.org/W2003720386","https://openalex.org/W2005808114","https://openalex.org/W2018764057","https://openalex.org/W2020506998","https://openalex.org/W2022159830","https://openalex.org/W2029972601","https://openalex.org/W2037562453","https://openalex.org/W2055826672","https://openalex.org/W2058159131","https://openalex.org/W2066272511","https://openalex.org/W2073588597","https://openalex.org/W2084666616","https://openalex.org/W2102397117","https://openalex.org/W2118274840","https://openalex.org/W2120196642","https://openalex.org/W2146304086","https://openalex.org/W2161603660","https://openalex.org/W2418035508","https://openalex.org/W2576378049","https://openalex.org/W2598520882","https://openalex.org/W4248715188","https://openalex.org/W4253427643"],"related_works":["https://openalex.org/W2020506998","https://openalex.org/W2899247281","https://openalex.org/W2080876349","https://openalex.org/W4284900120","https://openalex.org/W1579236972","https://openalex.org/W2570621389","https://openalex.org/W89234713","https://openalex.org/W2003720386","https://openalex.org/W2334849220","https://openalex.org/W2898238212"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"assess":[2],"associations":[3],"between":[4],"age-related":[5,230],"macular":[6,231],"degeneration":[7,232],"(AMD)":[8],"and":[9,11,19,74,108,143,173,206,214,227],"ocular":[10],"general":[12],"parameters.":[13],"METHODS:":[14],"The":[15],"Central":[16,28],"India":[17],"Eye":[18],"Medical":[20],"Study,":[21],"a":[22,132,238],"population-based":[23],"study":[24],"performed":[25],"in":[26,68,79,119,126,263],"rural":[27],"India,":[29],"included":[30],"4711":[31],"subjects":[32,40,70],"(aged":[33],"30+":[34],"years)":[35],"out":[36],"of":[37,90,152,166,178,182,189,200,211,241],"5885":[38],"eligible":[39],"(response":[41],"rate:":[42],"80.1%).":[43],"Fundus":[44,56],"photographs":[45,57],"were":[46,58],"assessed":[47],"using":[48],"the":[49,201,220,255],"Wisconsin":[50],"Age-Related":[51],"Maculopathy":[52],"Grading":[53],"system.":[54],"RESULTS:":[55],"available":[59],"for":[60,87,225,261],"4542":[61],"(96.4%)":[62],"subjects.":[63,84],"Early":[64],"AMD":[65,76,91,156,262],"was":[66,77,92,129,157,223,233,254],"present":[67],"215/4542":[69],"(4.7":[71],"\u00b1":[72,82],"0.3%),":[73],"late":[75],"detected":[78],"8/4542":[80],"(0.2":[81],"0.03%)":[83],"After":[85],"adjustment":[86],"age,":[88],"prevalence":[89],"significantly":[93,159,235],"associated":[94,130,160,236,259],"with":[95,131,161,237],"hyperopic":[96,120],"refractive":[97,111,228],"error":[98],"(p":[99,105,113,243],"=":[100,106,114,244],"0.001),":[101],"shorter":[102],"axial":[103,127,250],"length":[104,128],"0.01),":[107],"higher":[109],"corneal":[110],"power":[112],"0.02).":[115],"Each":[116],"dioptre":[117],"increase":[118],"refraction":[121],"or":[122,188],"each":[123],"millimetre":[124],"decrease":[125],"15%":[133],"[odds":[134],"ratio":[135],"(OR):1.15;":[136],"95%":[137],"confidence":[138],"interval":[139],"(CI):":[140],"1.06,":[141],"1.24]":[142],"19%":[144],"(OR:":[145],"0.81;":[146],"95%CI:":[147],"0.69,":[148],"0.95)":[149],"increased":[150],"probability":[151],"early":[153],"AMD,":[154],"respectively.":[155],"not":[158],"blood":[162],"pressure,":[163,198],"serum":[164],"concentration":[165],"cholesterol,":[167],"glycosylated":[168],"haemoglobin":[169],"Hb1Ac,":[170],"high-density":[171],"lipoproteins":[172],"postprandial":[174],"glucose,":[175],"gender,":[176],"level":[177],"education,":[179],"any":[180],"parameter":[181],"smoking,":[183],"alcohol":[184],"consumption,":[185],"psychiatric":[186],"depression":[187],"daily":[190],"activities,":[191],"anterior":[192],"chamber":[193],"depth,":[194],"lens":[195],"thickness,":[196],"intraocular":[197],"size":[199],"optic":[202],"disc,":[203],"neuroretinal":[204],"rim":[205],"parapapillary":[207],"atrophy,":[208],"nor":[209],"amount":[210],"nuclear":[212],"cataract":[213,217],"status":[215],"after":[216],"surgery.":[218],"If":[219],"statistical":[221],"analysis":[222],"adjusted":[224],"age":[226,253],"error,":[229],"marginally":[234],"low":[239],"intake":[240],"fruits":[242],"0.06).":[245],"CONCLUSIONS:":[246],"Hyperopia":[247],"(and":[248],"short":[249],"length)":[251],"besides":[252],"single":[256],"most":[257],"important":[258],"factor":[260],"adult":[264],"Indians.":[265]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}