{"id":"https://openalex.org/W2024306347","doi":"https://doi.org/10.4161/adip.24472","title":"Loss of adipocyte specification and necrosis augment tumor-associated inflammation","display_name":"Loss of adipocyte specification and necrosis augment tumor-associated inflammation","publication_year":2013,"publication_date":"2013-04-19","ids":{"openalex":"https://openalex.org/W2024306347","doi":"https://doi.org/10.4161/adip.24472","mag":"2024306347","pmid":"https://pubmed.ncbi.nlm.nih.gov/23991365","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3756107"},"language":"en","primary_location":{"id":"doi:10.4161/adip.24472","doi":"https://doi.org/10.4161/adip.24472","is_oa":true,"landing_page_url":"https://doi.org/10.4161/adip.24472","pdf_url":null,"source":{"id":"https://openalex.org/S4210208160","display_name":"Adipocyte","issn_l":"2162-3945","issn":["2162-3945","2162-397X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adipocyte","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.4161/adip.24472","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005670415","display_name":"Marek Wagner","orcid":"https://orcid.org/0000-0003-3967-9527","observed_orcids":["https://orcid.org/0000-0003-3967-9527"]},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Marek Wagner","raw_affiliation_strings":["Department of Biomedicine; University of Bergen; Bergen, Norway","Bergen, Norway","Department of Biomedicine","University of Bergen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine; University of Bergen; Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Bergen, Norway","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedicine","institution_ids":[]},{"raw_affiliation_string":"University of Bergen","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065173224","display_name":"Rolf Bjerkvig","orcid":"https://orcid.org/0000-0002-9622-7263","observed_orcids":["https://orcid.org/0000-0002-9622-7263"]},"institutions":[{"id":"https://openalex.org/I4405259354","display_name":"Centre de Recherche Public de la Sant\u00e9","ror":"https://ror.org/02485re30","country_code":"LU","type":"nonprofit","lineage":["https://openalex.org/I4210101141","https://openalex.org/I4405259354"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["LU","NO"],"is_corresponding":false,"raw_author_name":"Rolf Bjerkvig","raw_affiliation_strings":["Department of Biomedicine; University of Bergen; Bergen, Norway; Centre de Recherch\u00e9 Public de la Sant\u00e9; Luxembourg, Luxembourg","Bergen, Norway","Centre de Recherch\u00e9 Public de la Sant\u00e9","Department of Biomedicine","Luxembourg, Luxembourg","University of Bergen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine; University of Bergen; Bergen, Norway; Centre de Recherch\u00e9 Public de la Sant\u00e9; Luxembourg, Luxembourg","institution_ids":["https://openalex.org/I4405259354","https://openalex.org/I4432739"]},{"raw_affiliation_string":"Bergen, Norway","institution_ids":[]},{"raw_affiliation_string":"Centre de Recherch\u00e9 Public de la Sant\u00e9","institution_ids":["https://openalex.org/I4405259354"]},{"raw_affiliation_string":"Department of Biomedicine","institution_ids":[]},{"raw_affiliation_string":"Luxembourg, Luxembourg","institution_ids":[]},{"raw_affiliation_string":"University of Bergen","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017154970","display_name":"Helge Wiig","orcid":"https://orcid.org/0000-0002-7740-8210","observed_orcids":["https://orcid.org/0000-0002-7740-8210"]},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Helge Wiig","raw_affiliation_strings":["Department of Biomedicine; University of Bergen; Bergen, Norway","Bergen, Norway","Department of Biomedicine","University of Bergen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine; University of Bergen; Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Bergen, Norway","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedicine","institution_ids":[]},{"raw_affiliation_string":"University of Bergen","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084586982","display_name":"Andrew C. Dudley","orcid":"https://orcid.org/0000-0002-2663-1949","observed_orcids":["https://orcid.org/0000-0002-2663-1949"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew C Dudley","raw_affiliation_strings":["Department of Cell Biology & Physiology; Lineberger Comprehensive Cancer Center & McAllister Heart Institute; The University of North Carolina at Chapel Hill; Chapel Hill, NC USA","Chapel Hill, NC USA","Department of Cell Biology & Physiology","Lineberger Comprehensive Cancer Center & McAllister Heart Institute","The University of North Carolina at Chapel Hill"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology & Physiology; Lineberger Comprehensive Cancer Center & McAllister Heart Institute; The University of North Carolina at Chapel Hill; Chapel Hill, NC USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]},{"raw_affiliation_string":"Chapel Hill, NC USA","institution_ids":[]},{"raw_affiliation_string":"Department of Cell Biology & Physiology","institution_ids":[]},{"raw_affiliation_string":"Lineberger Comprehensive Cancer Center & McAllister Heart Institute","institution_ids":["https://openalex.org/I4390039329"]},{"raw_affiliation_string":"The University of North Carolina at Chapel Hill","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5084586982"],"corresponding_institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4390039329"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":{"value":2085,"currency":"GBP","value_usd":2557},"fwci":1.1657,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.76090237,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"2","issue":"3","first_page":"176","last_page":"183"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.029600000008940697,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adipocyte-necrosis","display_name":"adipocyte necrosis","score":0.8799999952316284},{"id":"https://openalex.org/keywords/tumor-inflammation","display_name":"tumor inflammation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hmgb1","display_name":"HMGB1","score":0.9509999752044678},{"id":"https://openalex.org/keywords/perilipin-1","display_name":"PLIN1","score":1.0},{"id":"https://openalex.org/keywords/macrophage-differentiation","display_name":"macrophage differentiation","score":0.8009999990463257},{"id":"https://openalex.org/keywords/foam-cells","display_name":"foam cells","score":0.7490000128746033},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8379999995231628},{"id":"https://openalex.org/keywords/monocyte-macrophage-differentiation","display_name":"monocyte-to-macrophage differentiation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6439999938011169},{"id":"https://openalex.org/keywords/adipocyte-dysfunction","display_name":"adipocyte dysfunction","score":0.640999972820282},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.8710137605667114},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.8416064977645874},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6634032130241394},{"id":"https://openalex.org/C17675752","wikidata":"https://www.wikidata.org/wiki/Q12898553","display_name":"Adipose tissue macrophages","level":4,"score":0.6613165140151978},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6610673666000366},{"id":"https://openalex.org/C39567582","wikidata":"https://www.wikidata.org/wiki/Q415624","display_name":"Perilipin","level":4,"score":0.6193147897720337},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5137215852737427},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.510877788066864},{"id":"https://openalex.org/C2776187077","wikidata":"https://www.wikidata.org/wiki/Q1888235","display_name":"Mammary tumor","level":4,"score":0.49729421734809875},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42827308177948},{"id":"https://openalex.org/C151955695","wikidata":"https://www.wikidata.org/wiki/Q654528","display_name":"White adipose tissue","level":3,"score":0.3966050446033478},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3736358880996704},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3630691170692444},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35994771122932434},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3295016884803772},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3212684392929077},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24572962522506714},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2289811372756958},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20297250151634216},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.11465299129486084},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.10546624660491943},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07382231950759888}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4161/adip.24472","doi":"https://doi.org/10.4161/adip.24472","is_oa":true,"landing_page_url":"https://doi.org/10.4161/adip.24472","pdf_url":null,"source":{"id":"https://openalex.org/S4210208160","display_name":"Adipocyte","issn_l":"2162-3945","issn":["2162-3945","2162-397X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adipocyte","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2746823","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3756107","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3756107","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3756107","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adipocyte","raw_type":"Text"},{"id":"pmid:23991365","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23991365","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adipocyte","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4161/adip.24472","doi":"https://doi.org/10.4161/adip.24472","is_oa":true,"landing_page_url":"https://doi.org/10.4161/adip.24472","pdf_url":null,"source":{"id":"https://openalex.org/S4210208160","display_name":"Adipocyte","issn_l":"2162-3945","issn":["2162-3945","2162-397X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adipocyte","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.979200005531311}],"study_designs":[],"awards":[{"id":"https://openalex.org/G256197783","display_name":"Tumor endothelial cell abnormalities","funder_award_id":"R00CA140708","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4593638316","display_name":"Characterizing tumor endothelial cell abnormalities to develop rational anti-angi","funder_award_id":"K99CA140708","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320310016","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993"},{"id":"https://openalex.org/F4320322496","display_name":"Helse Vest","ror":"https://ror.org/001212e83"},{"id":"https://openalex.org/F4320326507","display_name":"Haukeland\u00a0Universitetssjukehus","ror":"https://ror.org/03np4e098"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1480357432","https://openalex.org/W1495991289","https://openalex.org/W1539469412","https://openalex.org/W1967193940","https://openalex.org/W1982484787","https://openalex.org/W1987237299","https://openalex.org/W1989935936","https://openalex.org/W2004266769","https://openalex.org/W2004750645","https://openalex.org/W2016948425","https://openalex.org/W2018653121","https://openalex.org/W2039694476","https://openalex.org/W2041237929","https://openalex.org/W2052268920","https://openalex.org/W2058429236","https://openalex.org/W2058648826","https://openalex.org/W2062809449","https://openalex.org/W2080860848","https://openalex.org/W2097391811","https://openalex.org/W2115226530","https://openalex.org/W2118278569","https://openalex.org/W2129973062","https://openalex.org/W2130223580","https://openalex.org/W2135071303","https://openalex.org/W2141189887","https://openalex.org/W2145736817","https://openalex.org/W2147593845","https://openalex.org/W2152099551","https://openalex.org/W2159841585","https://openalex.org/W2163327518","https://openalex.org/W2164463026","https://openalex.org/W2164714222","https://openalex.org/W2171028311"],"related_works":["https://openalex.org/W1989935936","https://openalex.org/W4310195632","https://openalex.org/W2754569537","https://openalex.org/W2166845850","https://openalex.org/W2115226530","https://openalex.org/W3173929868","https://openalex.org/W2109921808","https://openalex.org/W4306964782","https://openalex.org/W1968243582","https://openalex.org/W7095798540"],"abstract_inverted_index":{"Most":[0],"tumors":[1,158],"are":[2,77],"typified":[3],"by":[4,38],"a":[5],"chronic,":[6],"unresolved":[7],"inflammatory":[8],"response":[9],"that":[10,21,88],"potentiates":[11],"angiogenesis":[12],"and":[13,40,52,72,98,115,123,136,144],"therefore":[14],"enables":[15],"tumor":[16,31,154],"progression.":[17],"We":[18],"have":[19],"determined":[20],"dysfunctional":[22],"tumor-associated":[23,27,33,66,89,106,147],"adipocytes":[24],"contribute":[25],"to":[26,119,146],"inflammation.":[28,148],"In":[29,83],"three":[30],"models,":[32],"adipose":[34,67,90,104,107,162],"tissue":[35,68,91,108],"was":[36,117],"characterized":[37],"thin":[39],"fragile":[41],"adipocyte":[42,133,139,150],"membranes,":[43],"necrosis,":[44,135],"robust":[45],"expression":[46],"of":[47,54,113,132,138],"the":[48,55],"pro-inflammatory":[49],"factor":[50],"HMGB1,":[51],"loss":[53,131],"lipid":[56,70,99],"storage":[57],"mediator,":[58],"perilipin-1.":[59],"By":[60],"transmission":[61],"electron":[62],"microscopy,":[63],"macrophages":[64,143],"in":[65,80,129,157,164],"contained":[69],"droplets":[71],"resembled":[73],"foam":[74],"cells,":[75],"which":[76],"commonly":[78],"observed":[79],"inflamed":[81],"tissues.":[82],"vitro":[84],"co-culture":[85],"studies":[86],"showed":[87],"conditioned-medium":[92],"stimulated":[93],"monocyte-to-macrophage":[94],"differentiation,":[95],"adhesion,":[96],"spreading,":[97],"uptake.":[100],"Compared":[101],"with":[102,161],"normal":[103],"tissue,":[105,163],"secreted":[109],"3-fold":[110],"higher":[111],"levels":[112],"IL-6":[114,116],"sufficient":[118],"stimulate":[120],"macrophage":[121],"differentiation":[122],"adhesion.":[124],"These":[125],"results":[126],"suggest":[127],"that,":[128],"tumors,":[130],"specification,":[134],"scavenging":[137],"debris":[140],"directly":[141],"activates":[142],"contributes":[145],"Thus,":[149],"dysfunction":[151],"may":[152],"facilitate":[153],"progression,":[155],"especially":[156],"closely":[159],"aligned":[160],"particular,":[165],"breast":[166],"cancer.":[167]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}