{"id":"https://openalex.org/W2024202074","doi":"https://doi.org/10.1016/j.bbmt.2013.12.397","title":"Post-Transplant Isoagglutinin Induced Pure Red Cell Aplasia; Incidence and Clinic Outcomes","display_name":"Post-Transplant Isoagglutinin Induced Pure Red Cell Aplasia; Incidence and Clinic Outcomes","publication_year":2014,"publication_date":"2014-02-01","ids":{"openalex":"https://openalex.org/W2024202074","doi":"https://doi.org/10.1016/j.bbmt.2013.12.397","mag":"2024202074"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2013.12.397","doi":"https://doi.org/10.1016/j.bbmt.2013.12.397","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.12.397","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2013.12.397","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043633072","display_name":"Samith Thomas Kochuparambil","orcid":"https://orcid.org/0009-0003-2189-7304","observed_orcids":["https://orcid.org/0009-0003-2189-7304"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samith Kochuparambil","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085360755","display_name":"Mark Robert Litzow","orcid":"https://orcid.org/0000-0002-9816-6302","observed_orcids":["https://orcid.org/0000-0002-9816-6302"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark R. Litzow","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084606047","display_name":"William J. Hogan","orcid":"https://orcid.org/0000-0002-5841-4105","observed_orcids":["https://orcid.org/0000-0002-5841-4105"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Hogan","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043033429","display_name":"Shahrukh Khurshid Hashmi","orcid":"https://orcid.org/0000-0002-8914-7927","observed_orcids":["https://orcid.org/0000-0002-8914-7927"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahrukh Hashmi","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090561132","display_name":"Dennis A. Gastineau","orcid":"https://orcid.org/0000-0003-2250-9812","observed_orcids":["https://orcid.org/0000-0003-2250-9812"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis Gastineau","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072463255","display_name":"Mrinal M. Patnaik","orcid":"https://orcid.org/0000-0001-6998-662X","observed_orcids":["https://orcid.org/0000-0001-6998-662X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mrinal Patnaik","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11338017,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"2","first_page":"S237","last_page":"S237"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.14069999754428864,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abo-incompatibility","display_name":"ABO incompatibility","score":0.9359999895095825},{"id":"https://openalex.org/keywords/allogeneic-stem-cell-transplantation","display_name":"allogeneic stem cell transplantation","score":0.9800000190734863},{"id":"https://openalex.org/keywords/delayed-engraftment","display_name":"delayed engraftment","score":0.746999979019165},{"id":"https://openalex.org/keywords/transfusion-dependence","display_name":"transfusion dependence","score":0.8059999942779541},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.8629999756813049},{"id":"https://openalex.org/keywords/plasmapheresis","display_name":"plasmapheresis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/donor-lymphocyte-infusion","display_name":"donor lymphocyte infusion","score":0.8109999895095825},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.8420000076293945},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.8080000281333923}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9632624387741089},{"id":"https://openalex.org/C2777422296","wikidata":"https://www.wikidata.org/wiki/Q751631","display_name":"Pure red cell aplasia","level":3,"score":0.832269549369812},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.5660018920898438},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5462808012962341},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.48017778992652893},{"id":"https://openalex.org/C2910652704","wikidata":"https://www.wikidata.org/wiki/Q17002910","display_name":"ABO incompatibility","level":3,"score":0.4763332009315491},{"id":"https://openalex.org/C176080213","wikidata":"https://www.wikidata.org/wiki/Q188010","display_name":"ABO blood group system","level":2,"score":0.47553563117980957},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.47090721130371094},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4441837966442108},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.19194447994232178},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.1486981213092804}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bbmt.2013.12.397","doi":"https://doi.org/10.1016/j.bbmt.2013.12.397","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.12.397","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2013.12.397","doi":"https://doi.org/10.1016/j.bbmt.2013.12.397","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.12.397","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410828330","https://openalex.org/W4386282287","https://openalex.org/W2000046518","https://openalex.org/W1984738674","https://openalex.org/W3156858905","https://openalex.org/W2592873500","https://openalex.org/W1979506066","https://openalex.org/W2011377953","https://openalex.org/W2363812612","https://openalex.org/W4400262291"],"abstract_inverted_index":{"ABO":[0,62,69,79,183,216],"incompatibility":[1,80],"among":[2,36],"patients":[3,72,193],"(pts)":[4],"undergoing":[5,38],"allogeneic":[6],"stem":[7,93],"cell":[8,20,91],"transplant":[9],"(ASCT)":[10],"is":[11,176,188],"associated":[12],"with":[13,60,67,119,129,139,194],"delayed":[14],"engraftment":[15],"and":[16,32,46,63,95,121,132,144,150],"post-transplant":[17],"pure":[18],"red":[19,90],"aplasia":[21],"(PT-PRCA).":[22],"After":[23,161,242],"due":[24],"IRB":[25],"approval":[26],"we":[27,56],"retrospectively":[28],"analyzed":[29],"the":[30,54],"prevalence":[31],"outcome":[33],"of":[34,49,100,113,159,169,181,239],"PT-PRCA":[35,114,170,175,197],"pts":[37,59,66,88,104,152,164],"ASCT":[39,51],"at":[40,234],"Mayo":[41],"Clinic,":[42],"Rochester":[43],"between":[44],"1/1/2000":[45],"9/30/2013.":[47],"Out":[48],"886":[50],"done":[52],"during":[53],"period,":[55],"identified":[57],"53(6%)":[58],"major":[61,78,182],"24":[64],"(3%)":[65],"bi-directional":[68,195],"incompatibility.":[70,196],"Twelve":[71],"(1%)":[73],"developed":[74],"PT-PRCA;":[75],"11":[76],"had":[77,83],"while":[81],"one":[82],"a":[84,280],"bidirectional":[85],"mismatch.":[86],"All":[87],"received":[89],"depleted":[92],"cells":[94],"there":[96],"were":[97,126,137],"no":[98],"cases":[99,136],"acute":[101],"hemolysis.":[102],"Six":[103],"underwent":[105],"reduced":[106],"intensity":[107],"conditioning.":[108],"Median":[109],"time":[110,166],"to":[111,157,167,227,237],"diagnosis":[112],"was":[115,171],"42":[116],"days":[117,173],"(23-67),":[118],"reticulocytopenia":[120],"renewed":[122,200],"transfusion":[123,201],"dependance.":[124,202],"Pts":[125],"initially":[127],"managed":[128],"immunosuppression":[130],"taper":[131,204],"EPO":[133],"supplementation.":[134],"Refractory":[135],"treated":[138],"plasmapheresis":[140],"(4),":[141],"rituximab":[142],"(6)":[143],"DLI":[145],"(1).":[146],"One":[147],"pt":[148],"relapsed":[149],"2":[151],"died":[153],"(both":[154],"sepsis)":[155],"prior":[156],"resolution":[158,168,238],"PT-PRCA.":[160],"excluding":[162],"these":[163],"median":[165],"113":[172],"(13-429).":[174],"not":[177],"an":[178],"uncommon":[179],"complication":[180],"incompatible":[184],"ASCT.":[185],"However":[186],"it":[187],"relatively":[189],"less":[190],"common":[191],"in":[192,199,279],"results":[198],"Immunosuppression":[203],"and/or":[205],"immunomodulation":[206],"can":[207],"serve":[208],"as":[209],"effective":[210],"treatment":[211],"strategies.Tabled":[212],"1Age\u0394Gender":[213],"Mis":[214],"matchHLA":[215],"Bi":[217],"Dir":[218],"MismatchCond.":[219],"RegimenStem":[220],"CellGVHD":[221],"GradePre":[222],"Transplant":[223],"titreRx":[224],"(In":[225],"addition":[226],"Taper":[228],"Immuno":[229],"Suppression)PRCA":[230],"Diagnosed":[231],"(Day)Retci":[232],"count":[233],"PRCA":[235,240,243],"DiagnosisTime":[236],"(Days)#PRBC":[241],"DiagnosisPost-Transplant":[244],"Survival":[245],"(Days)":[246],"*Died43AMLM-->F10/10MUD":[247],"A+/O+Flu/BuPBSCTSkin":[248],"2256PLX,":[249],"Rituximab":[250],"DLI+350.311222122860AMLM-->F10/10MUD":[251],"A+/O+Flu/BuPBSCTNo1024Rituximab+23<.281661227338AMLM->M9/10MUD":[252],"A+/O+Flu":[253],"TBIPBSCTNo512None+34<.281091822544AMLM-->F10/10MRD":[254],"AB+/O+Cy/TBIPBSCTNo64Rituximab,":[255],"Darbepoetin+26<.28RelapsedNA104363AMLF-->M10/10MRD":[256],"A+/O+Flu/BuPBSCTNo>":[257],"2048Rituximab,":[258],"Darbepoetin+40<.28Transfusion":[259],"DependentNA114*57AMLM->M10/10MUD":[260],"A+/O+Flu/MelPBSCTSkin":[261],"11024Darbepoetin":[262],"Rituximab,":[263],"PLX+57<.2842972158368AMLM->M10/10MUD":[264],"B+/O+Flu/MelPBSCTSkin":[265],"11024None+56<.281451486751ALLM-->F10/10MUD":[266],"A+/O+Cy/TBIPBSCTNo1024Rituximab":[267],"Darbepoetin+52<.28Transfusion":[268],"DependentNA315*63ALLM-->F10/10MUD":[269],"A+/O+Cy/TBIBMSCTSkin":[270],"1UKDarbepoetin+45<.28184264347CMLM->M10/10MUD":[271],"B-/A+":[272],"Bi-DirCy/TBIPBSCTNoNegPLX+67<.28177211*41MDSM->M10/10MUD":[273],"AB+/O+Cy/BuPBSCTNo256PLX+49<.281161761433MDSM->M10/10MUD":[274],"A+/O+Pent/TBIPBSCTGI":[275],"1NegDarbepoetin+37<.28134431*":[276],"Open":[277],"table":[278],"new":[281],"tab":[282]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}