{"id":"https://openalex.org/W2023938245","doi":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","title":"Homozygous Deletion of the Immunoglobulin C\u03b31 Gene","display_name":"Homozygous Deletion of the Immunoglobulin C\u03b31 Gene","publication_year":1988,"publication_date":"1988-12-01","ids":{"openalex":"https://openalex.org/W2023938245","doi":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","mag":"2023938245"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1988.tb21650.x","doi":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"C. I. EEVARD SMITH","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"C. I. EEVARD SMITH","raw_affiliation_strings":["Department of Clinical Immunology and Center for Biotechnology Karolinska Institute at Huddinge Hospital S-141 86 Huddinge. Sweden and Department of Immunology Stockholm University Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Immunology and Center for Biotechnology Karolinska Institute at Huddinge Hospital S-141 86 Huddinge. Sweden and Department of Immunology Stockholm University Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113699687","display_name":"Eva Fridell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"EVA FRIDELL","raw_affiliation_strings":["Department of Virology National Bacteriological Laboratory Stockholm. Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology National Bacteriological Laboratory Stockholm. Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053103667","display_name":"Annika Linde","orcid":"https://orcid.org/0000-0002-5749-4852","observed_orcids":["https://orcid.org/0000-0002-5749-4852"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ANNIKA LINDE","raw_affiliation_strings":["Department of Virology National Bacteriological Laboratory Stockholm. Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology National Bacteriological Laboratory Stockholm. Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007181851","display_name":"Tiit Illimar Mathiesen","orcid":"https://orcid.org/0000-0001-9463-1919","observed_orcids":["https://orcid.org/0000-0001-9463-1919"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"TIIT MATHIESEN","raw_affiliation_strings":["Department of Virology National Bacteriological Laboratory Stockholm. Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology National Bacteriological Laboratory Stockholm. Sweden","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008915149","display_name":"Lennart L G Hammarstr\u00f6m","orcid":"https://orcid.org/0000-0002-8635-9609","observed_orcids":["https://orcid.org/0000-0002-8635-9609"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"LENNART HAMMARSTR\u00d6M","raw_affiliation_strings":["Department of Clinical Immunology and Center for Biotechnology Karolinska Institute at Huddinge Hospital S-141 86 Huddinge. Sweden and Department of Immunology Stockholm University Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Immunology and Center for Biotechnology Karolinska Institute at Huddinge Hospital S-141 86 Huddinge. Sweden and Department of Immunology Stockholm University Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684","https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.1461,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39661586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"546","issue":"1","first_page":"232","last_page":"235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.02590000070631504,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homozygous-deletion","display_name":"homozygous deletion","score":0.8980000019073486},{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-constant-region","display_name":"immunoglobulin heavy chain constant region","score":0.6800000071525574},{"id":"https://openalex.org/keywords/immunoglobulin-deficiency","display_name":"antibody deficiency","score":0.4569999873638153},{"id":"https://openalex.org/keywords/primary-immunodeficiency","display_name":"primary immunodeficiency","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C2992965680","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Clinical microbiology","level":2,"score":0.5643439888954163},{"id":"https://openalex.org/C2994571964","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Clinical immunology","level":3,"score":0.553094208240509},{"id":"https://openalex.org/C2992786221","wikidata":"https://www.wikidata.org/wiki/Q849994","display_name":"Clinical biochemistry","level":2,"score":0.5101528763771057},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.49366435408592224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48365485668182373},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.34697225689888},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21389418840408325},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19705921411514282},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1684975028038025},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.08502444624900818},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.07029810547828674},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1111/j.1749-6632.1988.tb21650.x","doi":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1988.tb21650.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W321160890","https://openalex.org/W1526373153","https://openalex.org/W1598631917","https://openalex.org/W1826181374","https://openalex.org/W1986059203","https://openalex.org/W2002164913","https://openalex.org/W2008843978","https://openalex.org/W2051587759","https://openalex.org/W2095000631","https://openalex.org/W2151759979","https://openalex.org/W2163294806","https://openalex.org/W2415343017","https://openalex.org/W2419366115"],"related_works":["https://openalex.org/W2419012095","https://openalex.org/W4235140847","https://openalex.org/W2428688238","https://openalex.org/W7217945525","https://openalex.org/W1955354299","https://openalex.org/W2095000631","https://openalex.org/W2026823646","https://openalex.org/W321160890","https://openalex.org/W7101096083","https://openalex.org/W2400124516"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}