{"id":"https://openalex.org/W2023924196","doi":"https://doi.org/10.1117/12.44296","title":"Novel method for the computer analysis of cryomicroscopic images","display_name":"Novel method for the computer analysis of cryomicroscopic images","publication_year":1991,"publication_date":"1991-07-01","ids":{"openalex":"https://openalex.org/W2023924196","doi":"https://doi.org/10.1117/12.44296","mag":"2023924196"},"language":"en","primary_location":{"id":"doi:10.1117/12.44296","doi":"https://doi.org/10.1117/12.44296","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.44296","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001447073","display_name":"Wei R. Chen","orcid":"https://orcid.org/0000-0002-7133-5794","observed_orcids":["https://orcid.org/0000-0002-7133-5794"]},"institutions":[{"id":"https://openalex.org/I4210135723","display_name":"Shanghai Institute of Technical Physics","ror":"https://ror.org/02txedb84","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210135723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei R. Chen","raw_affiliation_strings":["Shanghai Institute of Technical Physics (China)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Institute of Technical Physics (China)","institution_ids":["https://openalex.org/I4210135723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113107883","display_name":"Yiming Gong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135723","display_name":"Shanghai Institute of Technical Physics","ror":"https://ror.org/02txedb84","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210135723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiming Gong","raw_affiliation_strings":["Shanghai Institute of Technical Physics (China)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Institute of Technical Physics (China)","institution_ids":["https://openalex.org/I4210135723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011459080","display_name":"Ruli Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135723","display_name":"Shanghai Institute of Technical Physics","ror":"https://ror.org/02txedb84","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210135723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruli Wang","raw_affiliation_strings":["Shanghai Institute of Technical Physics (China)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Institute of Technical Physics (China)","institution_ids":["https://openalex.org/I4210135723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088451672","display_name":"Yayong Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113094","display_name":"Shanghai Blood Center","ror":"https://ror.org/01cyxs230","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210113094"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yayong Xu","raw_affiliation_strings":["Shanghai Blood Research Ctr. (China)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Blood Research Ctr. (China)","institution_ids":["https://openalex.org/I4210113094"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.22818792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1450","issue":null,"first_page":"198","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.8345000147819519,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.8345000147819519,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.11460000276565552,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11897","display_name":"Digital Holography and Microscopy","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryomicroscopy","display_name":"cryomicroscopy","score":0.8510000109672546},{"id":"https://openalex.org/keywords/cell-size-measurement","display_name":"cell size measurement","score":0.8360000252723694},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"image segmentation","score":0.7239999771118164},{"id":"https://openalex.org/keywords/cell-image-analysis","display_name":"cell image analysis","score":0.5590000152587891},{"id":"https://openalex.org/keywords/low-signal-to-noise-ratio-images","display_name":"low signal-to-noise ratio images","score":0.847000002861023},{"id":"https://openalex.org/keywords/computer-image-analysis","display_name":"computer image analysis","score":0.5669999718666077}],"concepts":[{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.6361494064331055},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6029788255691528},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.5445960760116577},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5441466569900513},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.49662119150161743},{"id":"https://openalex.org/C13944312","wikidata":"https://www.wikidata.org/wiki/Q7512748","display_name":"Signal-to-noise ratio (imaging)","level":2,"score":0.4950501024723053},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.38397735357284546},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.34717047214508057},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.326571524143219},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.16172504425048828},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.09620752930641174}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.44296","doi":"https://doi.org/10.1117/12.44296","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.44296","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2122930345","https://openalex.org/W1985163414","https://openalex.org/W2055716330","https://openalex.org/W2411414086","https://openalex.org/W2028222148","https://openalex.org/W2744760624","https://openalex.org/W2036144824","https://openalex.org/W7167790871","https://openalex.org/W7099662043","https://openalex.org/W1988596999"],"abstract_inverted_index":{"A":[0],"novel":[1],"method":[2,54],"has":[3],"been":[4],"developed":[5],"to":[6,58],"quantitatively":[7],"measure":[8],"cell":[9,62],"size":[10],"from":[11,34],"the":[12,19,42,59],"photomicrographs":[13],"taken":[14,66],"at":[15],"regular":[16],"intervals":[17],"during":[18],"processes":[20],"of":[21,29,44,61],"freeze-thaw":[22],"experiments":[23],"on":[24],"a":[25,73],"cryomicroscope.":[26],"The":[27,48],"images":[28,63],"cells":[30,45],"are":[31,46],"easily":[32],"outlined":[33],"pictures":[35],"with":[36],"poor":[37],"signal-":[38],"to-noise":[39],"ratio":[40],"and":[41],"sizes":[43],"computed.":[47],"results":[49],"have":[50],"demonstrated":[51],"that":[52],"this":[53],"is":[55],"particularly":[56],"suitable":[57],"analysis":[60],"which":[64],"were":[65],"under":[67],"adverse":[68],"conditions--poorly":[69],"focused":[70],"or":[71],"in":[72,80],"very":[74],"dusty":[75],"environment,":[76],"situations":[77],"occurring":[78],"frequently":[79],"cryomicroscopic":[81],"measurement.":[82]},"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}