{"id":"https://openalex.org/W2023537745","doi":"https://doi.org/10.3109/00016489.2010.490240","title":"Management of stage I/II hypopharyngeal cancer","display_name":"Management of stage I/II hypopharyngeal cancer","publication_year":2010,"publication_date":"2010-09-29","ids":{"openalex":"https://openalex.org/W2023537745","doi":"https://doi.org/10.3109/00016489.2010.490240","mag":"2023537745","pmid":"https://pubmed.ncbi.nlm.nih.gov/20879818"},"language":"en","primary_location":{"id":"doi:10.3109/00016489.2010.490240","doi":"https://doi.org/10.3109/00016489.2010.490240","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00016489.2010.490240","pdf_url":null,"source":{"id":"https://openalex.org/S198335345","display_name":"Acta Oto-Laryngologica","issn_l":"0001-6489","issn":["0001-6489","1651-2251","1651-2553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Oto-Laryngologica","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2023537745"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035027343","display_name":"Morimasa Kitamura","orcid":"https://orcid.org/0000-0002-4875-4165","observed_orcids":["https://orcid.org/0000-0002-4875-4165"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Morimasa Kitamura","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Kyoto University, Kyoto, Japan. m_kitamura@ent.kuhp.kyoto-u.ac.jp","Department of Otolaryngology-Head & Neck Surgery, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Kyoto University, Kyoto, Japan. m_kitamura@ent.kuhp.kyoto-u.ac.jp","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Department of Otolaryngology-Head & Neck Surgery, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049580701","display_name":"Shigeru Hirano","orcid":"https://orcid.org/0000-0003-1737-6613","observed_orcids":["https://orcid.org/0000-0003-1737-6613"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeru Hirano","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065938624","display_name":"Ichiro Tateya","orcid":"https://orcid.org/0000-0003-4737-4811","observed_orcids":["https://orcid.org/0000-0003-4737-4811"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ichiro Tateya","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059163462","display_name":"Shinpei Kada","orcid":"https://orcid.org/0000-0002-3296-2736","observed_orcids":["https://orcid.org/0000-0002-3296-2736"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinpei Kada","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102958603","display_name":"Seiji Ishikawa","orcid":"https://orcid.org/0000-0003-2553-4861","observed_orcids":["https://orcid.org/0000-0003-2553-4861"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Seiji Ishikawa","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112068348","display_name":"Tomoko Kanda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoko Kanda","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108724068","display_name":"Shinzo Tanaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinzo Tanaka","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110369776","display_name":"Juichi Ito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Juichi Ito","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5035027343"],"corresponding_institution_ids":["https://openalex.org/I22299242"],"apc_list":null,"apc_paid":null,"fwci":0.6815,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.71319479,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"130","issue":"sup563","first_page":"43","last_page":"49"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypopharyngeal-cancer","display_name":"hypopharyngeal cancer","score":0.9089999794960022},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.8629999756813049},{"id":"https://openalex.org/keywords/surgical-treatment","display_name":"surgical treatment","score":0.7860000133514404},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.9620000123977661},{"id":"https://openalex.org/keywords/laryngeal-preservation","display_name":"laryngeal preservation","score":0.8700000047683716},{"id":"https://openalex.org/keywords/disease-specific-survival","display_name":"disease-specific survival","score":0.9750000238418579},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.7310000061988831},{"id":"https://openalex.org/keywords/salvage-surgery","display_name":"salvage surgery","score":0.9599999785423279},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.728574812412262},{"id":"https://openalex.org/C2779196318","wikidata":"https://www.wikidata.org/wiki/Q1393463","display_name":"Hypopharyngeal cancer","level":3,"score":0.6821880340576172},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5255157947540283},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.35848158597946167},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35648056864738464},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.341871052980423},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16217494010925293},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007012","descriptor_name":"Hypopharyngeal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007012","descriptor_name":"Hypopharyngeal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007012","descriptor_name":"Hypopharyngeal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010611","descriptor_name":"Pharyngectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/00016489.2010.490240","doi":"https://doi.org/10.3109/00016489.2010.490240","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00016489.2010.490240","pdf_url":null,"source":{"id":"https://openalex.org/S198335345","display_name":"Acta Oto-Laryngologica","issn_l":"0001-6489","issn":["0001-6489","1651-2251","1651-2553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Oto-Laryngologica","raw_type":"journal-article"},{"id":"pmid:20879818","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20879818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta oto-laryngologica. Supplementum","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1967889486","https://openalex.org/W1972814245","https://openalex.org/W2010840705","https://openalex.org/W2022395184","https://openalex.org/W2026725699","https://openalex.org/W2065071659","https://openalex.org/W2137185830","https://openalex.org/W2161189218","https://openalex.org/W2315304171","https://openalex.org/W2768455041"],"related_works":["https://openalex.org/W2141860328","https://openalex.org/W2135355869","https://openalex.org/W2165725108","https://openalex.org/W2161189218","https://openalex.org/W1968571197","https://openalex.org/W2315547854","https://openalex.org/W1993546732","https://openalex.org/W2563100632","https://openalex.org/W2069825846","https://openalex.org/W2262115807"],"abstract_inverted_index":{"CONCLUSIONS:":[0],"It":[1],"is":[2],"suggested":[3],"that":[4,17],"radiotherapy":[5,73,94],"might":[6,20],"be":[7,21],"the":[8,34,96,156],"first":[9],"choice":[10],"for":[11,23,76,82],"stage":[12,24,45,51,55,71,91,125,135,146,163],"I/II":[13,46],"hypopharyngeal":[14,39,47],"cancer,":[15],"and":[16,65,79,95,108,114,130],"adjuvant":[18],"treatment":[19,81],"necessary":[22],"II":[25,92,136,147,164],"patients":[26,43],"to":[27,155],"prevent":[28],"distant":[29],"metastasis.":[30],"OBJECTIVES:":[31],"To":[32],"update":[33],"therapeutic":[35],"outcome":[36],"of":[37,87,141],"early":[38],"cancer.":[40],"METHODS:":[41],"Twenty-eight":[42],"with":[44,138],"cancer":[48],"(8":[49],"in":[50,54,70,90,121,124,131,134,145,159,162],"I,":[52,72],"20":[53,88],"II)":[56],"were":[57,112,119,148],"treated":[58,127,137],"at":[59],"Kyoto":[60],"University":[61],"Hospital":[62],"between":[63],"1995":[64],"2007.":[66],"Of":[67],"8":[68],"cases":[69,89,99,123,133,144,161],"was":[74],"applied":[75],"4":[77],"cases,":[78],"surgical":[80],"another":[83],"4,":[84],"while":[85],"13":[86],"underwent":[93,100],"remaining":[97],"7":[98],"surgery.":[101,152],"RESULTS:":[102],"The":[103],"5-year":[104],"cumulative":[105],"disease-specific":[106],"survival":[107],"larynx":[109],"preservation":[110],"rates":[111],"74.6%":[113],"73.2%,":[115],"respectively.":[116],"Recurrent":[117],"tumors":[118],"found":[120],"two":[122,160],"I":[126],"by":[128,150],"surgery":[129],"five":[132,142],"radiotherapy.":[139],"Two":[140],"recurrent":[143],"rescued":[149],"salvage":[151],"Distant":[153],"metastasis":[154],"lung":[157],"appeared":[158],"after":[165],"initial":[166],"treatment.":[167]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}