{"id":"https://openalex.org/W2023212836","doi":"https://doi.org/10.1002/cplu.201290014","title":"Cover Picture: Probing Wavelength Regulation with an Engineered Rhodopsin Mimic and a C15-Retinal Analogue (ChemPlusChem 4/2012)","display_name":"Cover Picture: Probing Wavelength Regulation with an Engineered Rhodopsin Mimic and a C15-Retinal Analogue (ChemPlusChem 4/2012)","publication_year":2012,"publication_date":"2012-04-01","ids":{"openalex":"https://openalex.org/W2023212836","doi":"https://doi.org/10.1002/cplu.201290014","mag":"2023212836"},"language":"en","primary_location":{"id":"doi:10.1002/cplu.201290014","doi":"https://doi.org/10.1002/cplu.201290014","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cplu.201290014","pdf_url":null,"source":{"id":"https://openalex.org/S163199293","display_name":"ChemPlusChem","issn_l":"2192-6506","issn":["2192-6506"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemPlusChem","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cplu.201290019","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064274524","display_name":"Kin Sing Stephen Lee","orcid":"https://orcid.org/0000-0003-4541-3063","observed_orcids":["https://orcid.org/0000-0003-4541-3063"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kin Sing S. Lee","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018686367","display_name":"Tetyana Berbasova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tetyana Berbasova","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001811134","display_name":"Chrysoula Vasileiou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chrysoula Vasileiou","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090658404","display_name":"Xiaofei Jia","orcid":"https://orcid.org/0000-0003-1224-4742","observed_orcids":["https://orcid.org/0000-0003-1224-4742"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofei Jia","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014177505","display_name":"Wenjing Wang","orcid":"https://orcid.org/0000-0001-6025-9848","observed_orcids":["https://orcid.org/0000-0001-6025-9848"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenjing Wang","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021112785","display_name":"Yoomi Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoomi Choi","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075791174","display_name":"Farid Nossoni","orcid":"https://orcid.org/0000-0003-2157-2078","observed_orcids":["https://orcid.org/0000-0003-2157-2078"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farid Nossoni","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051291962","display_name":"James H. Geiger","orcid":"https://orcid.org/0000-0002-9443-4488","observed_orcids":["https://orcid.org/0000-0002-9443-4488"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James H. Geiger","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052952898","display_name":"Babak Borhan","orcid":"https://orcid.org/0000-0002-3193-0732","observed_orcids":["https://orcid.org/0000-0002-3193-0732"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Babak Borhan","raw_affiliation_strings":["Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA),","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Chemistry, Michigan State University, East Lansing, MI 48824 (USA), Fax: (+1)\u2009517\u2010353\u20101793","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051291962","https://openalex.org/A5052952898"],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08552907,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":"4","first_page":"249","last_page":"249"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11708","display_name":"Photochromic and Fluorescence Chemistry","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crabp2","display_name":"CRABP2","score":0.8109999895095825},{"id":"https://openalex.org/keywords/lysine-side-chain","display_name":"lysine side chain","score":0.9399999976158142},{"id":"https://openalex.org/keywords/color-vision","display_name":"color vision","score":0.5320000052452087},{"id":"https://openalex.org/keywords/protein-engineering","display_name":"protein engineering","score":0.460999995470047},{"id":"https://openalex.org/keywords/retinal-chromophore","display_name":"retinal chromophore","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C192468462","wikidata":"https://www.wikidata.org/wiki/Q533543","display_name":"Chromophore","level":2,"score":0.795674204826355},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6616329550743103},{"id":"https://openalex.org/C2780428219","wikidata":"https://www.wikidata.org/wiki/Q16952335","display_name":"Cover (algebra)","level":2,"score":0.6302632093429565},{"id":"https://openalex.org/C202033177","wikidata":"https://www.wikidata.org/wiki/Q423107","display_name":"Rhodopsin","level":3,"score":0.6294397115707397},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41161245107650757},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3605528175830841},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.32236266136169434},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.3078235685825348},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11571884155273438},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10152798891067505},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/cplu.201290014","doi":"https://doi.org/10.1002/cplu.201290014","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cplu.201290014","pdf_url":null,"source":{"id":"https://openalex.org/S163199293","display_name":"ChemPlusChem","issn_l":"2192-6506","issn":["2192-6506"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemPlusChem","raw_type":"journal-article"},{"id":"doi:10.1002/cplu.201290019","doi":"https://doi.org/10.1002/cplu.201290019","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cplu.201290019","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cplu.201290019","source":{"id":"https://openalex.org/S163199293","display_name":"ChemPlusChem","issn_l":"2192-6506","issn":["2192-6506"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemPlusChem","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/cplu.201290019","doi":"https://doi.org/10.1002/cplu.201290019","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cplu.201290019","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cplu.201290019","source":{"id":"https://openalex.org/S163199293","display_name":"ChemPlusChem","issn_l":"2192-6506","issn":["2192-6506"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemPlusChem","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2023212836.pdf","grobid_xml":"https://content.openalex.org/works/W2023212836.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2055754364","https://openalex.org/W6963665614","https://openalex.org/W2344199141","https://openalex.org/W2042393505","https://openalex.org/W2081150812","https://openalex.org/W1854833491","https://openalex.org/W2031210068","https://openalex.org/W3004730351","https://openalex.org/W1994209732","https://openalex.org/W2046420311"],"abstract_inverted_index":{"The":[0,24,38],"cover":[1],"picture":[2],"shows":[3],"a":[4,13,47],"short,":[5],"C15-retinal":[6,32],"analogue":[7,33],"bound":[8],"as":[9],"an":[10,28],"iminium":[11],"to":[12,45],"lysine":[14],"side":[15],"chain":[16],"from":[17],"the":[18,35,41,59,65],"crystal":[19],"structure":[20],"of":[21,50],"reengineered":[22],"CRABPII.":[23],"\u2018caged\u2019":[25],"chromophore":[26],"represents":[27],"embedded":[29],"and":[30,77],"solvent-shielded":[31],"inside":[34],"protein":[36,61],"cavity.":[37],"background":[39],"stresses":[40],"human":[42],"eye's":[43],"ability":[44,53],"perceive":[46],"wide":[48],"range":[49],"colors.":[51],"This":[52],"is":[54],"in":[55,58,64],"part":[56],"mimicked":[57],"designed":[60],"system":[62],"described":[63],"Communication":[66],"on":[67],"page":[68],"273":[69],"ff.":[70],"by":[71],"J.":[72],"H.":[73],"Geiger,":[74],"B.":[75],"Borhan,":[76],"co-workers.":[78]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}