{"id":"https://openalex.org/W2023093450","doi":"https://doi.org/10.1016/j.jmb.2009.04.027","title":"Ca2+-Dependent Photocrosslinking of Tropomyosin Residue 146 to Residues 157\u2013163 in the C-Terminal Domain of Troponin I in Reconstituted Skeletal Muscle Thin Filaments","display_name":"Ca2+-Dependent Photocrosslinking of Tropomyosin Residue 146 to Residues 157\u2013163 in the C-Terminal Domain of Troponin I in Reconstituted Skeletal Muscle Thin Filaments","publication_year":2009,"publication_date":"2009-04-20","ids":{"openalex":"https://openalex.org/W2023093450","doi":"https://doi.org/10.1016/j.jmb.2009.04.027","mag":"2023093450","pmid":"https://pubmed.ncbi.nlm.nih.gov/19379756","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2805953"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmb.2009.04.027","doi":"https://doi.org/10.1016/j.jmb.2009.04.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmb.2009.04.027","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2805953","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070159472","display_name":"Wasana A. K. A. Mudalige","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1309400984","display_name":"Boston Biomedical Research Institute","ror":"https://ror.org/04rqpth59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1309400984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wasana A.K.A. Mudalige","raw_affiliation_strings":["Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA","institution_ids":["https://openalex.org/I1309400984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103557558","display_name":"Terence C. Tao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1309400984","display_name":"Boston Biomedical Research Institute","ror":"https://ror.org/04rqpth59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1309400984"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terence C. Tao","raw_affiliation_strings":["Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA","Department of Biochemistry, Tufts University School of Medicine, Boston, MA 02111, USA","Department of Neurology, Harvard Medical School, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA","institution_ids":["https://openalex.org/I1309400984"]},{"raw_affiliation_string":"Department of Biochemistry, Tufts University School of Medicine, Boston, MA 02111, USA","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064474716","display_name":"Sherwin S. Lehrer","orcid":"https://orcid.org/0000-0002-0284-4472","observed_orcids":["https://orcid.org/0000-0002-0284-4472"]},"institutions":[{"id":"https://openalex.org/I1309400984","display_name":"Boston Biomedical Research Institute","ror":"https://ror.org/04rqpth59","country_code":"US","type":"facility","lineage":["https://openalex.org/I1309400984"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sherwin S. Lehrer","raw_affiliation_strings":["Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA","Department of Neurology, Harvard Medical School, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Program, Boston Biomedical Research Institute, Watertown, MA 02472, USA","institution_ids":["https://openalex.org/I1309400984"]},{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5064474716"],"corresponding_institution_ids":["https://openalex.org/I1309400984","https://openalex.org/I136199984"],"apc_list":{"value":4730,"currency":"USD","value_usd":4730},"apc_paid":null,"fwci":2.9706,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.91637637,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"389","issue":"3","first_page":"575","last_page":"583"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.08649999648332596,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/troponin-i","display_name":"troponin I","score":0.8709999918937683},{"id":"https://openalex.org/keywords/tropomyosin","display_name":"tropomyosin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/c-terminal-domain","display_name":"C-terminal domain","score":0.8069999814033508},{"id":"https://openalex.org/keywords/actin-tropomyosin-interaction","display_name":"actin-tropomyosin interaction","score":0.8529999852180481},{"id":"https://openalex.org/keywords/photo-crosslinking","display_name":"photocrosslinking","score":0.8159999847412109},{"id":"https://openalex.org/keywords/troponin-c","display_name":"troponin C","score":0.7760000228881836},{"id":"https://openalex.org/keywords/troponin-t","display_name":"troponin T","score":0.9929999709129333},{"id":"https://openalex.org/keywords/actin","display_name":"actin","score":0.382999986410141},{"id":"https://openalex.org/keywords/muscle-contraction-regulation","display_name":"muscle contraction regulation","score":0.7360000014305115},{"id":"https://openalex.org/keywords/tryptic-peptide-identification","display_name":"tryptic peptide identification","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.8265770673751831},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6557647585868835},{"id":"https://openalex.org/C205875245","wikidata":"https://www.wikidata.org/wiki/Q418454","display_name":"Tropomyosin","level":3,"score":0.6434133052825928},{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.5892919301986694},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5677266716957092},{"id":"https://openalex.org/C115725540","wikidata":"https://www.wikidata.org/wiki/Q7846263","display_name":"Troponin I","level":3,"score":0.537492573261261},{"id":"https://openalex.org/C36036425","wikidata":"https://www.wikidata.org/wiki/Q7846262","display_name":"Troponin","level":3,"score":0.5359092354774475},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2740332782268524},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09474274516105652},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010782","descriptor_name":"Photolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014335","descriptor_name":"Tropomyosin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014335","descriptor_name":"Tropomyosin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D014335","descriptor_name":"Tropomyosin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019210","descriptor_name":"Troponin I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019210","descriptor_name":"Troponin I","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D019210","descriptor_name":"Troponin I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jmb.2009.04.027","doi":"https://doi.org/10.1016/j.jmb.2009.04.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmb.2009.04.027","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},{"id":"pmid:19379756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19379756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2805953","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2805953","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Mol Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2805953","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2805953","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Mol Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2332034925","display_name":"Tropomyosin and the Regulation of Muscle Contraction","funder_award_id":"R01HL022461","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2787224892","display_name":"Molecular Mechanism of Smooth Muscle Regulation","funder_award_id":"P01AR041637","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3940482308","display_name":"Mechanism of Calcium Regulation in Striated Muscle","funder_award_id":"R01AR049066","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G7366394207","display_name":"PROXIMITY RELATIONSHIPS AMONG MUSCLE PROTEINS","funder_award_id":"R37AR021673","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W196269325","https://openalex.org/W1481760785","https://openalex.org/W1538692246","https://openalex.org/W1554913126","https://openalex.org/W1576830579","https://openalex.org/W1901823973","https://openalex.org/W1970400205","https://openalex.org/W1971055882","https://openalex.org/W1971187965","https://openalex.org/W1974842879","https://openalex.org/W1979028003","https://openalex.org/W1984540887","https://openalex.org/W1986574046","https://openalex.org/W1989461632","https://openalex.org/W1992924616","https://openalex.org/W2000888880","https://openalex.org/W2004033858","https://openalex.org/W2004243471","https://openalex.org/W2004561249","https://openalex.org/W2008476079","https://openalex.org/W2017556218","https://openalex.org/W2036451625","https://openalex.org/W2046296155","https://openalex.org/W2048114117","https://openalex.org/W2055002273","https://openalex.org/W2059086329","https://openalex.org/W2066000309","https://openalex.org/W2074345274","https://openalex.org/W2139292873","https://openalex.org/W2164269007","https://openalex.org/W2324460644","https://openalex.org/W2336273353","https://openalex.org/W2346785564"],"related_works":["https://openalex.org/W1984776015","https://openalex.org/W2069858863","https://openalex.org/W2003380170","https://openalex.org/W2013672801","https://openalex.org/W1974842879","https://openalex.org/W2049093260","https://openalex.org/W1594626340","https://openalex.org/W2001815679","https://openalex.org/W3136622967","https://openalex.org/W2059501161"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}