{"id":"https://openalex.org/W2022494892","doi":"https://doi.org/10.1016/0278-5846(91)90049-7","title":"The changes of thyroid hormone during pharmacological treatment of panic disorder patients","display_name":"The changes of thyroid hormone during pharmacological treatment of panic disorder patients","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W2022494892","doi":"https://doi.org/10.1016/0278-5846(91)90049-7","mag":"2022494892","pmid":"https://pubmed.ncbi.nlm.nih.gov/1956988"},"language":"en","primary_location":{"id":"doi:10.1016/0278-5846(91)90049-7","doi":"https://doi.org/10.1016/0278-5846(91)90049-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0278-5846(91)90049-7","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014898527","display_name":"Richard Balon","orcid":"https://orcid.org/0000-0001-6598-2242","observed_orcids":["https://orcid.org/0000-0001-6598-2242"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Balon","raw_affiliation_strings":["Department of Psychiatry, Wayne State University, Detroit, Michigan","Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Wayne State University, Detroit, Michigan","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057935101","display_name":"Robert B. Pohl","orcid":"https://orcid.org/0000-0001-8370-6233","observed_orcids":["https://orcid.org/0000-0001-8370-6233"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Pohl","raw_affiliation_strings":["Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112101929","display_name":"Vikram Kumar Yeragani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vikram K. Yeragani","raw_affiliation_strings":["Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031701630","display_name":"Chilakamarri Ramesh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chilakamarri Ramesh","raw_affiliation_strings":["Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052721902","display_name":"Debra A. Glitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Debra A. Glitz","raw_affiliation_strings":["Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Wayne State University and Lafayette Clinic Lafayette, Detroit, Michigan, U.S.A","institution_ids":["https://openalex.org/I185443292"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185443292"],"apc_list":{"value":4380,"currency":"USD","value_usd":4380},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.11640772,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"15","issue":"5","first_page":"595","last_page":"600"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":0.9079999923706055},{"id":"https://openalex.org/keywords/imipramine","display_name":"imipramine","score":0.9319999814033508},{"id":"https://openalex.org/keywords/diazepam","display_name":"diazepam","score":0.9829999804496765},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.8420000076293945},{"id":"https://openalex.org/keywords/free-thyroxine-index","display_name":"free thyroxine index","score":0.7900000214576721},{"id":"https://openalex.org/keywords/serum-thyroxine","display_name":"serum thyroxine","score":0.652999997138977},{"id":"https://openalex.org/keywords/antidepressant-side-effects","display_name":"antidepressant side effects","score":0.7450000047683716},{"id":"https://openalex.org/keywords/drug-induced-hypothyroidism","display_name":"drug-induced hypothyroidism","score":0.6779999732971191},{"id":"https://openalex.org/keywords/placebo-effect","display_name":"placebo effect","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C2779145073","wikidata":"https://www.wikidata.org/wiki/Q58396","display_name":"Imipramine","level":3,"score":0.9464177489280701},{"id":"https://openalex.org/C2776175493","wikidata":"https://www.wikidata.org/wiki/Q210402","display_name":"Diazepam","level":2,"score":0.8208725452423096},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.738867461681366},{"id":"https://openalex.org/C2780712732","wikidata":"https://www.wikidata.org/wiki/Q208450","display_name":"Panic","level":3,"score":0.7334561347961426},{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.6721498966217041},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.6421241760253906},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5587401390075684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5448465347290039},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5384789109230042},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.53118896484375},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42193442583084106},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27725279331207275},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.258357435464859},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.16448670625686646},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003975","descriptor_name":"Diazepam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003975","descriptor_name":"Diazepam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007773","descriptor_name":"Lactates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0278-5846(91)90049-7","doi":"https://doi.org/10.1016/0278-5846(91)90049-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0278-5846(91)90049-7","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},{"id":"pmid:1956988","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1956988","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in neuro-psychopharmacology & biological psychiatry","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G816591901","display_name":null,"funder_award_id":"42099","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W173093647","https://openalex.org/W1983617877","https://openalex.org/W2000579856","https://openalex.org/W2002100129","https://openalex.org/W2005446659","https://openalex.org/W2012215723","https://openalex.org/W2032449240","https://openalex.org/W2040696004","https://openalex.org/W2044264234","https://openalex.org/W2059793415","https://openalex.org/W2160070901","https://openalex.org/W2416013525","https://openalex.org/W2426156544","https://openalex.org/W2462863614"],"related_works":["https://openalex.org/W4252664664","https://openalex.org/W2042420222","https://openalex.org/W2060004382","https://openalex.org/W2006313794","https://openalex.org/W1986112574","https://openalex.org/W2417826260","https://openalex.org/W1985705000","https://openalex.org/W2162161566","https://openalex.org/W1974739856","https://openalex.org/W2060876079"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}