{"id":"https://openalex.org/W2022494035","doi":"https://doi.org/10.1007/bf02983792","title":"Pseudoprolongation of the Prothrombin Time During Treatment with Recombinant Factor VIIa for Bleeding in a Patient with a Spontaneous Factor VIII Inhibitor","display_name":"Pseudoprolongation of the Prothrombin Time During Treatment with Recombinant Factor VIIa for Bleeding in a Patient with a Spontaneous Factor VIII Inhibitor","publication_year":2003,"publication_date":"2003-04-01","ids":{"openalex":"https://openalex.org/W2022494035","doi":"https://doi.org/10.1007/bf02983792","mag":"2022494035","pmid":"https://pubmed.ncbi.nlm.nih.gov/12731678"},"language":"en","primary_location":{"id":"doi:10.1007/bf02983792","doi":"https://doi.org/10.1007/bf02983792","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02983792","pdf_url":null,"source":{"id":"https://openalex.org/S45192162","display_name":"International Journal of Hematology","issn_l":"0925-5710","issn":["0925-5710","1865-3774"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Hematology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111713733","display_name":"Marcus E. Carr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcus E. Carr","raw_affiliation_strings":["Box 980230, 23298-0230, Richmond, Virginia, USA","Central Virginia Center for Coagulation Disorders, Richmond, Virginia, USA","Departments of aPathology, Richmond, Virginia, USA","Internal Medicine, Richmond, Virginia, USA","Virginia Commonwealth University, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Box 980230, 23298-0230, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Central Virginia Center for Coagulation Disorders, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Departments of aPathology, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Internal Medicine, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112144033","display_name":"Jan G. Kuhn","orcid":"https://orcid.org/0000-0002-5067-2943","observed_orcids":["https://orcid.org/0000-0002-5067-2943"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan G. Kuhn","raw_affiliation_strings":["Central Virginia Center for Coagulation Disorders, Richmond, Virginia, USA","Virginia Commonwealth University, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Virginia Center for Coagulation Disorders, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019968417","display_name":"Erika J. Martin","orcid":"https://orcid.org/0000-0002-6740-6000","observed_orcids":["https://orcid.org/0000-0002-6740-6000"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erika J. Martin","raw_affiliation_strings":["Departments of aPathology, Richmond, Virginia, USA","Virginia Commonwealth University, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of aPathology, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000501710","display_name":"Ann Tidwell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann R. Tidwell","raw_affiliation_strings":["Departments of aPathology, Richmond, Virginia, USA","Virginia Commonwealth University, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of aPathology, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Virginia Commonwealth University, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012710790","display_name":"Maura K. Hagane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098033","display_name":"Virginia Cancer Institute","ror":"https://ror.org/00st10j60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098033"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maura K. Hagane","raw_affiliation_strings":["Departments of aPathology, Richmond, Virginia, USA","Virginia Cancer Institute, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of aPathology, Richmond, Virginia, USA","institution_ids":[]},{"raw_affiliation_string":"Virginia Cancer Institute, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4210098033"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111713733"],"corresponding_institution_ids":["https://openalex.org/I184840846"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.4954,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.65541119,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":"3","first_page":"308","last_page":"309"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prolonged-prothrombin-time","display_name":"prothrombin time prolongation","score":0.8669999837875366},{"id":"https://openalex.org/keywords/recombinant-factor-viia","display_name":"recombinant factor VIIa","score":0.9750000238418579},{"id":"https://openalex.org/keywords/factor-viii-inhibitors","display_name":"factor VIII inhibitors","score":0.9010000228881836},{"id":"https://openalex.org/keywords/acquired-hemophilia","display_name":"acquired hemophilia","score":0.6129999756813049},{"id":"https://openalex.org/keywords/hemorrhage","display_name":"hemorrhage","score":0.5360000133514404},{"id":"https://openalex.org/keywords/coagulation-factor-replacement-therapy","display_name":"factor replacement therapy","score":0.48399999737739563},{"id":"https://openalex.org/keywords/acquired-coagulopathy","display_name":"acquired coagulopathy","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C2778961111","wikidata":"https://www.wikidata.org/wiki/Q5940878","display_name":"Recombinant factor VIIa","level":2,"score":0.9246317148208618},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7734365463256836},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.7372512817382812},{"id":"https://openalex.org/C2908626413","wikidata":"https://www.wikidata.org/wiki/Q412850","display_name":"Factor VIIa","level":4,"score":0.6773783564567566},{"id":"https://openalex.org/C2777091921","wikidata":"https://www.wikidata.org/wiki/Q2044524","display_name":"Prothrombin complex concentrate","level":4,"score":0.6156604886054993},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5365431904792786},{"id":"https://openalex.org/C2780930249","wikidata":"https://www.wikidata.org/wiki/Q412850","display_name":"Factor VII","level":3,"score":0.52752286195755},{"id":"https://openalex.org/C2780434524","wikidata":"https://www.wikidata.org/wiki/Q1144385","display_name":"Prothrombin time","level":2,"score":0.519045889377594},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46081772446632385},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.39717644453048706},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3789588212966919},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3776870369911194},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3234439492225647},{"id":"https://openalex.org/C186738567","wikidata":"https://www.wikidata.org/wiki/Q412841","display_name":"Tissue factor","level":3,"score":0.2027018666267395},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.17258545756340027},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.084644615650177},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05568447709083557},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003951","descriptor_name":"Diagnostic Errors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005167","descriptor_name":"Factor VII","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005169","descriptor_name":"Factor VIII","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006467","descriptor_name":"Hemophilia A","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007518","descriptor_name":"Isoantibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011517","descriptor_name":"Prothrombin Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015942","descriptor_name":"Factor VIIa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02983792","doi":"https://doi.org/10.1007/bf02983792","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02983792","pdf_url":null,"source":{"id":"https://openalex.org/S45192162","display_name":"International Journal of Hematology","issn_l":"0925-5710","issn":["0925-5710","1865-3774"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Hematology","raw_type":"journal-article"},{"id":"pmid:12731678","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12731678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of hematology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W69280588","https://openalex.org/W2044209579","https://openalex.org/W2052348646","https://openalex.org/W2114591836","https://openalex.org/W2167402278","https://openalex.org/W2327141062","https://openalex.org/W2327557830"],"related_works":["https://openalex.org/W2049439921","https://openalex.org/W2885820003","https://openalex.org/W4213416336","https://openalex.org/W1989174872","https://openalex.org/W2409726607","https://openalex.org/W1969728898","https://openalex.org/W2005841950","https://openalex.org/W2410884151","https://openalex.org/W2560034285","https://openalex.org/W2128406610"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}