{"id":"https://openalex.org/W2021829949","doi":"https://doi.org/10.1037//0735-7044.107.5.867","title":"Cocaine alters behavior in the rat fetus.","display_name":"Cocaine alters behavior in the rat fetus.","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2021829949","doi":"https://doi.org/10.1037//0735-7044.107.5.867","mag":"2021829949","pmid":"https://pubmed.ncbi.nlm.nih.gov/8280396"},"language":"en","primary_location":{"id":"doi:10.1037//0735-7044.107.5.867","doi":"https://doi.org/10.1037//0735-7044.107.5.867","is_oa":false,"landing_page_url":"https://doi.org/10.1037//0735-7044.107.5.867","pdf_url":null,"source":{"id":"https://openalex.org/S25269534","display_name":"Behavioral Neuroscience","issn_l":"0735-7044","issn":["0735-7044","1939-0084"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320262","host_organization_name":"American Psychological Association","host_organization_lineage":["https://openalex.org/P4310320262"],"host_organization_lineage_names":["American Psychological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioral Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074399561","display_name":"Diane K. Simonik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane K. Simonik","raw_affiliation_strings":["Department of Psychology, Binghamton University, New York 13902-6000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Binghamton University, New York 13902-6000","institution_ids":["https://openalex.org/I123946342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041961913","display_name":"Scott R. Robinson","orcid":"https://orcid.org/0000-0003-3821-850X","observed_orcids":["https://orcid.org/0000-0003-3821-850X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott R. Robinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000095813","display_name":"William P. Smotherman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William P. Smotherman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3739,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.91482157,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"107","issue":"5","first_page":"867","last_page":"875"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cocaine","display_name":"cocaine","score":0.8880000114440918},{"id":"https://openalex.org/keywords/prenatal-drug-exposure","display_name":"prenatal drug exposure","score":0.8100000023841858},{"id":"https://openalex.org/keywords/fetal-behavior","display_name":"fetal behavior","score":0.8040000200271606},{"id":"https://openalex.org/keywords/fetal-movement","display_name":"fetal movement","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cutaneous-sensitivity","display_name":"cutaneous sensitivity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/sensorimotor-integration","display_name":"sensorimotor integration","score":0.9169999957084656},{"id":"https://openalex.org/keywords/motor-coordination","display_name":"motor coordination","score":0.8169999718666077},{"id":"https://openalex.org/keywords/behavioral-development","display_name":"behavioral development","score":0.6200000047683716},{"id":"https://openalex.org/keywords/gestational-dose-response","display_name":"gestational dose-response","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.7694101929664612},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.5647298693656921},{"id":"https://openalex.org/C2988899074","wikidata":"https://www.wikidata.org/wiki/Q19595989","display_name":"Motor behavior","level":2,"score":0.5193620324134827},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.5108182430267334},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.49950480461120605},{"id":"https://openalex.org/C113062710","wikidata":"https://www.wikidata.org/wiki/Q2463100","display_name":"Motor coordination","level":2,"score":0.4790124297142029},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.46551135182380676},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.42181649804115295},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3519529104232788},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3273906111717224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30505385994911194},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.24052104353904724},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19127574563026428},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005314","descriptor_name":"Embryonic and Fetal Development","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005324","descriptor_name":"Fetal Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006120","descriptor_name":"Grooming","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013649","descriptor_name":"Taste","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014110","descriptor_name":"Touch","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1037//0735-7044.107.5.867","doi":"https://doi.org/10.1037//0735-7044.107.5.867","is_oa":false,"landing_page_url":"https://doi.org/10.1037//0735-7044.107.5.867","pdf_url":null,"source":{"id":"https://openalex.org/S25269534","display_name":"Behavioral Neuroscience","issn_l":"0735-7044","issn":["0735-7044","1939-0084"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320262","host_organization_name":"American Psychological Association","host_organization_lineage":["https://openalex.org/P4310320262"],"host_organization_lineage_names":["American Psychological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioral Neuroscience","raw_type":"journal-article"},{"id":"doi:10.1037/0735-7044.107.5.867","doi":"https://doi.org/10.1037/0735-7044.107.5.867","is_oa":false,"landing_page_url":"https://doi.org/10.1037/0735-7044.107.5.867","pdf_url":null,"source":{"id":"https://openalex.org/S25269534","display_name":"Behavioral Neuroscience","issn_l":"0735-7044","issn":["0735-7044","1939-0084"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320262","host_organization_name":"American Psychological Association","host_organization_lineage":["https://openalex.org/P4310320262"],"host_organization_lineage_names":["American Psychological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioral Neuroscience","raw_type":"journal-article"},{"id":"pmid:8280396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8280396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioral neuroscience","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2474879098","display_name":"BEHAVIORAL EFFECTS OF MILK IN THE FETUS","funder_award_id":"R01HD028231","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G3995802702","display_name":null,"funder_award_id":"HD 16102","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G5167259251","display_name":"INPUTS TO NEUROMUSCULAR AND BEHAVIORAL DEVELOPMENT","funder_award_id":"P01HD028014","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W318983315","https://openalex.org/W354711315","https://openalex.org/W581439905","https://openalex.org/W654339378","https://openalex.org/W1978776622","https://openalex.org/W1984123057"],"related_works":["https://openalex.org/W2078979901","https://openalex.org/W2397299030","https://openalex.org/W2061435228","https://openalex.org/W2009831226","https://openalex.org/W2012572548","https://openalex.org/W2066661887","https://openalex.org/W2070977609","https://openalex.org/W1990803948","https://openalex.org/W1996692576","https://openalex.org/W2004693414"],"abstract_inverted_index":{"Changes":[0,63],"in":[1,9,26,32,48,64,97],"motor":[2,28,91],"behavior":[3],"and":[4,39,55,58,72,113],"sensory":[5],"responsiveness":[6,60],"were":[7],"characterized":[8],"rat":[10],"fetuses":[11,70],"on":[12,109],"gestational":[13],"Day":[14],"21":[15],"after":[16],"acute":[17],"administration":[18],"of":[19,22,51,87,94,105],"various":[20],"doses":[21,36],"cocaine.":[23],"An":[24],"increase":[25],"fetal":[27],"activity":[29],"was":[30,82],"evident":[31],"the":[33,95,103],"3":[34],"highest":[35],"(5,":[37],"10,":[38],"20":[40,56],"mg/kg).":[41,62],"Cocaine-exposed":[42],"Ss":[43],"showed":[44],"reduced":[45,79],"facial":[46,80],"wiping":[47,81],"behavioral":[49,66,114],"bioassays":[50],"cutaneous":[52],"sensitivity":[53],"(10":[54],"mg/kg)":[57],"chemosensory":[59],"(20":[61],"other":[65],"measures":[67],"indicated":[68],"that":[69,78],"detected":[71],"responded":[73],"to":[74,84],"these":[75],"stimuli,":[76],"suggesting":[77],"due":[83],"a":[85],"disruption":[86],"sensorimotor":[88],"integration":[89],"or":[90],"coordination.":[92],"Study":[93],"fetus":[96],"vivo":[98],"can":[99],"provide":[100],"insights":[101],"into":[102],"mechanisms":[104],"cocaine's":[106],"deleterious":[107],"effects":[108],"central":[110],"nervous":[111],"system":[112],"development.":[115]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}