{"id":"https://openalex.org/W2021663202","doi":"https://doi.org/10.1006/jsbi.1997.3940","title":"High-Resolution Crystals of Methionine Aminopeptidase fromPyrococcus furiosusObtained by Water-Mediated Transformation","display_name":"High-Resolution Crystals of Methionine Aminopeptidase fromPyrococcus furiosusObtained by Water-Mediated Transformation","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2021663202","doi":"https://doi.org/10.1006/jsbi.1997.3940","mag":"2021663202","pmid":"https://pubmed.ncbi.nlm.nih.gov/9573622"},"language":"en","primary_location":{"id":"doi:10.1006/jsbi.1997.3940","doi":"https://doi.org/10.1006/jsbi.1997.3940","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jsbi.1997.3940","pdf_url":null,"source":{"id":"https://openalex.org/S89954039","display_name":"Journal of Structural Biology","issn_l":"1047-8477","issn":["1047-8477","1095-8657"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Structural Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005916247","display_name":"T.H. Tahirov","orcid":"https://orcid.org/0000-0002-1238-0069","observed_orcids":["https://orcid.org/0000-0002-1238-0069"]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tahir H Tahirov","raw_affiliation_strings":["Institute for Protein Research, Osaka University, Japan","Institute for Protein Research, Osaka University, 3-2 Yamadaoka Suita, Osaka, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Institute for Protein Research, Osaka University, 3-2 Yamadaoka Suita, Osaka, 565, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001043320","display_name":"Hideyuki Oki","orcid":"https://orcid.org/0000-0003-1927-053X","observed_orcids":["https://orcid.org/0000-0003-1927-053X"]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideyuki Oki","raw_affiliation_strings":["Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","Osaka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Osaka University","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080888597","display_name":"Tomitake Tsukihara A","orcid":"https://orcid.org/0000-0002-9478-0954","observed_orcids":["https://orcid.org/0000-0002-9478-0954"]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tomitake Tsukihara","raw_affiliation_strings":["Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","Osaka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Osaka University","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041279842","display_name":"Kyoko Ogasahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyoko Ogasahara","raw_affiliation_strings":["Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","Osaka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Osaka University","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028649351","display_name":"Katsuhide Yutani","orcid":"https://orcid.org/0000-0003-1645-6072","observed_orcids":["https://orcid.org/0000-0003-1645-6072"]},"institutions":[{"id":"https://openalex.org/I4405286456","display_name":"Institute for Protein Research, The University of Osaka","ror":"https://ror.org/0268snt13","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhide Yutani","raw_affiliation_strings":["Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","Osaka University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565, Japan","institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"]},{"raw_affiliation_string":"Osaka University","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030371324","display_name":"Clare Peters Libeu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180941496","display_name":"University of Hyogo","ror":"https://ror.org/0151bmh98","country_code":"JP","type":"education","lineage":["https://openalex.org/I180941496"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Clare Peters Libeu","raw_affiliation_strings":["Department of Life Science, Faculty of Science, Himeji Institute of Technology, Kamigori, Hyogo, 678-12, Japan","University of Hyogo;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, Faculty of Science, Himeji Institute of Technology, Kamigori, Hyogo, 678-12, Japan","institution_ids":[]},{"raw_affiliation_string":"University of Hyogo;","institution_ids":["https://openalex.org/I180941496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030157721","display_name":"Yukiko Izu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273692","display_name":"Takara Shuzo Co., Ltd. (Japan)","ror":"https://ror.org/009xcqz70","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukiko Izu","raw_affiliation_strings":["Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","Takara Shuzo Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","institution_ids":["https://openalex.org/I4405273692"]},{"raw_affiliation_string":"Takara Shuzo Co., Ltd","institution_ids":["https://openalex.org/I4405273692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056614311","display_name":"Susumu Tsunasawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273692","display_name":"Takara Shuzo Co., Ltd. (Japan)","ror":"https://ror.org/009xcqz70","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Susumu Tsunasawa","raw_affiliation_strings":["Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","Takara Shuzo Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","institution_ids":["https://openalex.org/I4405273692"]},{"raw_affiliation_string":"Takara Shuzo Co., Ltd","institution_ids":["https://openalex.org/I4405273692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102123010","display_name":"Ikunoshin Kato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273692","display_name":"Takara Shuzo Co., Ltd. (Japan)","ror":"https://ror.org/009xcqz70","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405273692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ikunoshin Kato","raw_affiliation_strings":["Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","Takara Shuzo Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Group, Takara Shuzo Company, Ltd. Seta 3-4-1, Otsu, Shiga, 520-21, Japan","institution_ids":["https://openalex.org/I4405273692"]},{"raw_affiliation_string":"Takara Shuzo Co., Ltd","institution_ids":["https://openalex.org/I4405273692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5080888597"],"corresponding_institution_ids":["https://openalex.org/I4405286456","https://openalex.org/I98285908"],"apc_list":{"value":4350,"currency":"USD","value_usd":4350},"apc_paid":null,"fwci":1.0102,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.73210412,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"121","issue":"1","first_page":"68","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methionine-aminopeptidase","display_name":"methionine aminopeptidase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pyrococcus-furiosus","display_name":"Pyrococcus furiosus","score":1.0},{"id":"https://openalex.org/keywords/solvent-content","display_name":"solvent content","score":0.5239999890327454},{"id":"https://openalex.org/keywords/crystal-mosaicity","display_name":"crystal mosaicity","score":0.7730000019073486},{"id":"https://openalex.org/keywords/high-resolution-crystal-structure","display_name":"high-resolution crystal structure","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2780912031","wikidata":"https://www.wikidata.org/wiki/Q180341","display_name":"Methionine","level":3,"score":0.6647052764892578},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.6405662298202515},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.5640748143196106},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4970710575580597},{"id":"https://openalex.org/C2780985610","wikidata":"https://www.wikidata.org/wiki/Q419527","display_name":"Aminopeptidase","level":4,"score":0.4189072251319885},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4153165817260742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35734522342681885},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3225407898426056},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30847257375717163},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.18964946269989014},{"id":"https://openalex.org/C2776580952","wikidata":"https://www.wikidata.org/wiki/Q483745","display_name":"Leucine","level":3,"score":0.15285730361938477},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.1319752037525177},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.08949631452560425},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.061100900173187256}],"mesh":[{"descriptor_ui":"D000626","descriptor_name":"Aminopeptidases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000626","descriptor_name":"Aminopeptidases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D003460","descriptor_name":"Crystallization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019711","descriptor_name":"Pyrococcus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D019711","descriptor_name":"Pyrococcus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063208","descriptor_name":"Methionyl Aminopeptidases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/jsbi.1997.3940","doi":"https://doi.org/10.1006/jsbi.1997.3940","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jsbi.1997.3940","pdf_url":null,"source":{"id":"https://openalex.org/S89954039","display_name":"Journal of Structural Biology","issn_l":"1047-8477","issn":["1047-8477","1095-8657"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Structural Biology","raw_type":"journal-article"},{"id":"pmid:9573622","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9573622","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of structural biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1528586913","https://openalex.org/W1964365676","https://openalex.org/W1975067598","https://openalex.org/W1976232903","https://openalex.org/W1981728432","https://openalex.org/W1996643987","https://openalex.org/W2002572115","https://openalex.org/W2008302186","https://openalex.org/W2014694459","https://openalex.org/W2039922865","https://openalex.org/W2052341984","https://openalex.org/W2053246850","https://openalex.org/W2060807817","https://openalex.org/W2064745948","https://openalex.org/W2072920353","https://openalex.org/W2077294102","https://openalex.org/W2170297840","https://openalex.org/W2425952260"],"related_works":["https://openalex.org/W2008302186","https://openalex.org/W1975055907","https://openalex.org/W1964365676","https://openalex.org/W1497297086","https://openalex.org/W2166203762","https://openalex.org/W2137559724","https://openalex.org/W4416292694","https://openalex.org/W1981673350","https://openalex.org/W2012197354","https://openalex.org/W2076157948"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}