{"id":"https://openalex.org/W2021648865","doi":"https://doi.org/10.1097/00000658-199603000-00014","title":"Alanyl-Glutamine Dipeptide-Supplemented Parenteral Nutrition Improves Intestinal Metabolism and Prevents Increased Permeability in Rats","display_name":"Alanyl-Glutamine Dipeptide-Supplemented Parenteral Nutrition Improves Intestinal Metabolism and Prevents Increased Permeability in Rats","publication_year":1996,"publication_date":"1996-03-01","ids":{"openalex":"https://openalex.org/W2021648865","doi":"https://doi.org/10.1097/00000658-199603000-00014","mag":"2021648865","pmid":"https://pubmed.ncbi.nlm.nih.gov/8604914","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1235122"},"language":"en","primary_location":{"id":"doi:10.1097/00000658-199603000-00014","doi":"https://doi.org/10.1097/00000658-199603000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000658-199603000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1235122/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113548427","display_name":"S. M. Manzurul Haque","orcid":"https://orcid.org/0000-0002-5096-3046","observed_orcids":["https://orcid.org/0000-0002-5096-3046"]},"institutions":[{"id":"https://openalex.org/I4210155576","display_name":"Osaka University Hospital","ror":"https://ror.org/05rnn8t74","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210155576","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"S. M. Manzurul Haque","raw_affiliation_strings":["Department of Pediatric Surgery, Osaka University Medical School, Japan","\"and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Surgery, Osaka University Medical School, Japan","institution_ids":["https://openalex.org/I4210155576","https://openalex.org/I98285908"]},{"raw_affiliation_string":"\"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050369131","display_name":"Kai Chen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kai Chen","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083444050","display_name":"Noriaki Usui","orcid":"https://orcid.org/0000-0003-1498-1762","observed_orcids":["https://orcid.org/0000-0003-1498-1762"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Noriaki Usui","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113945079","display_name":"Yasuhiko Iiboshi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yasuhiko Iiboshi","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039525605","display_name":"Hiroomi Okuyama","orcid":"https://orcid.org/0000-0002-1347-282X","observed_orcids":["https://orcid.org/0000-0002-1347-282X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hiroomi Okuyama","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048543064","display_name":"Akira Masunari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Akira Masunari","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Li Cui","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Li Cui","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008803613","display_name":"Riichiro Nezu","orcid":"https://orcid.org/0000-0003-4489-4272","observed_orcids":["https://orcid.org/0000-0003-4489-4272"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Riichiro Nezu","raw_affiliation_strings":["Osaka University Medical School, Osaka, Japan","\"Osaka University Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka University Medical School, Osaka, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"\"Osaka University Medical School","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102252668","display_name":"Yoji Takagi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yoji Takagi","raw_affiliation_strings":["and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054898922","display_name":"Akira Okada","orcid":"https://orcid.org/0000-0001-5740-4346","observed_orcids":["https://orcid.org/0000-0001-5740-4346"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Akira Okada","raw_affiliation_strings":["Address reprint requests to Akira Okada, M.D., F.A.C.S., Department of Pediatric Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita- Shi, Osaka 565, Japan","and The First Department of Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address reprint requests to Akira Okada, M.D., F.A.C.S., Department of Pediatric Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita- Shi, Osaka 565, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"and The First Department of Surgery","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039525605","https://openalex.org/A5048543064","https://openalex.org/A5050369131","https://openalex.org/A5054898922","https://openalex.org/A5083444050","https://openalex.org/A5102252668","https://openalex.org/A5113548427","https://openalex.org/A5113945079"],"corresponding_institution_ids":["https://openalex.org/I4210155576","https://openalex.org/I98285908"],"apc_list":null,"apc_paid":null,"fwci":3.1772,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.91366358,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"223","issue":"3","first_page":"334","last_page":"341"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alanyl-glutamine","display_name":"alanyl-glutamine","score":0.9700000286102295},{"id":"https://openalex.org/keywords/total-parenteral-nutrition","display_name":"total parenteral nutrition","score":0.9620000123977661},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.9639999866485596},{"id":"https://openalex.org/keywords/intestinal-mucosa","display_name":"intestinal mucosa","score":0.7820000052452087},{"id":"https://openalex.org/keywords/glutamine-metabolism","display_name":"glutamine metabolism","score":0.871999979019165},{"id":"https://openalex.org/keywords/intestinal-blood-flow","display_name":"intestinal blood flow","score":0.6679999828338623},{"id":"https://openalex.org/keywords/jejunal-mucosa","display_name":"jejunal mucosa","score":0.7570000290870667},{"id":"https://openalex.org/keywords/mucosal-atrophy","display_name":"mucosal atrophy","score":0.7889999747276306},{"id":"https://openalex.org/keywords/fitc-dextran","display_name":"FITC-dextran","score":0.8159999847412109},{"id":"https://openalex.org/keywords/d-xylose","display_name":"D-xylose","score":0.9129999876022339},{"id":"https://openalex.org/keywords/glutaminase-activity","display_name":"glutaminase activity","score":0.7120000123977661}],"concepts":[{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.9286377429962158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6569033265113831},{"id":"https://openalex.org/C2781071285","wikidata":"https://www.wikidata.org/wiki/Q17141320","display_name":"Intestinal permeability","level":2,"score":0.6326119899749756},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5632622838020325},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.5304082632064819},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.48921990394592285},{"id":"https://openalex.org/C2779138802","wikidata":"https://www.wikidata.org/wiki/Q418602","display_name":"Dipeptide","level":3,"score":0.45153623819351196},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.440863698720932},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37622982263565063},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2804562449455261},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17612570524215698}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002463","descriptor_name":"Cell Membrane Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004151","descriptor_name":"Dipeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004151","descriptor_name":"Dipeptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005772","descriptor_name":"Gastrointestinal Transit","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007408","descriptor_name":"Intestinal Absorption","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010289","descriptor_name":"Parenteral Nutrition, Total","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/00000658-199603000-00014","doi":"https://doi.org/10.1097/00000658-199603000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000658-199603000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},{"id":"pmid:8604914","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8604914","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of surgery","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1235122","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1235122/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Surg","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1235122","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1235122/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Surg","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W19494609","https://openalex.org/W44457639","https://openalex.org/W112984908","https://openalex.org/W1521429354","https://openalex.org/W1572100925","https://openalex.org/W1596308403","https://openalex.org/W1726400177","https://openalex.org/W1861210509","https://openalex.org/W1966608688","https://openalex.org/W1971017288","https://openalex.org/W1983671706","https://openalex.org/W1984725896","https://openalex.org/W1996822066","https://openalex.org/W2001909228","https://openalex.org/W2003918651","https://openalex.org/W2013688192","https://openalex.org/W2022454750","https://openalex.org/W2040711680","https://openalex.org/W2040953278","https://openalex.org/W2046247654","https://openalex.org/W2052896018","https://openalex.org/W2055447706","https://openalex.org/W2059325107","https://openalex.org/W2064081814","https://openalex.org/W2067878478","https://openalex.org/W2071106723","https://openalex.org/W2071485163","https://openalex.org/W2075861648","https://openalex.org/W2095421059","https://openalex.org/W2100200241","https://openalex.org/W2118719572","https://openalex.org/W2128635872","https://openalex.org/W2169002591","https://openalex.org/W2170142830","https://openalex.org/W2328023807","https://openalex.org/W2406997480","https://openalex.org/W2414447617","https://openalex.org/W2418509640","https://openalex.org/W2419673296","https://openalex.org/W2438875723","https://openalex.org/W2439474492","https://openalex.org/W2464283917","https://openalex.org/W4249405083"],"related_works":["https://openalex.org/W2007788600","https://openalex.org/W2055447706","https://openalex.org/W2017486954","https://openalex.org/W2003799771","https://openalex.org/W2081035197","https://openalex.org/W2378512910","https://openalex.org/W1887405687","https://openalex.org/W1986307931","https://openalex.org/W2075574715","https://openalex.org/W2052896018"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1],"authors":[2],"determined":[3],"the":[4,19,43,56,104,118,141,160,166,175],"effects":[5],"of":[6,18,59,152,171,188],"alanyl-glutamine-supplemented":[7],"total":[8],"parenteral":[9],"nutrition":[10],"(TPN)":[11],"on":[12],"mucosal":[13,124,127,145,184],"metabolism,":[14],"integrity,":[15],"and":[16,53,62,77,86,110,129,131,148,182,186],"permeability":[17],"small":[20],"intestine":[21],"in":[22,103,134,140,159],"rats.":[23],"METHODS:":[24],"Male":[25],"Sprague-Dawley":[26],"rats":[27],"were":[28,51,66,81,91,137,156],"randomized":[29],"to":[30,174],"receive":[31],"TPN":[32,176],"supplemented":[33,46],"with":[34,47,93,165],"a":[35],"conventional":[36],"amino":[37],"acids":[38],"mixture":[39],"(STD":[40],"group)":[41],"or":[42],"same":[44],"solution":[45,177],"alanyl-glutamine;":[48],"both":[49],"solutions":[50],"isocaloric":[52],"isonitrogenous.":[54],"On":[55],"seventh":[57],"day":[58],"TPN,":[60],"D-xylose":[61,76,112],"fluorescein":[63],"isothiocyanate":[64],"(FITC)-dextran":[65],"administered":[67],"orally.":[68],"One":[69],"hour":[70],"later,":[71],"superior":[72],"mesenteric":[73],"vein":[74],"(SMV)":[75],"plasma":[78],"FITC-dextran":[79,100],"concentration":[80,113],"measured.":[82],"Intestinal":[83,107],"blood":[84,108],"flow":[85,109],"calculated":[87],"intestinal":[88,150,179],"substrates":[89],"flux":[90],"measured":[92],"ultrasonic":[94],"transit":[95],"time":[96],"flowmetery.":[97],"RESULTS:":[98],"Plasma":[99],"increased":[101,139],"significantly":[102,138,157],"STD":[105,167],"group.":[106,143,168],"SMV":[111],"did":[114],"not":[115],"differ":[116],"between":[117],"groups.":[119],"Mucosa":[120],"weight,":[121],"villus":[122],"height,":[123],"wall":[125],"thickness,":[126],"protein,":[128],"DNA":[130],"RNA":[132],"content":[133],"jejunal":[135],"mucosa":[136],"alanyl-glutamine":[142,161,172],"Jejunal":[144],"glutaminase":[146],"activity":[147],"net":[149],"uptake":[151],"glutamine":[153,180],"(glutamine":[154],"flux)":[155],"higher":[158],"group":[162],"as":[163],"compared":[164],"CONCLUSION:":[169],"Addition":[170],"dipeptide":[173],"improves":[178],"metabolism":[181],"prevents":[183],"atrophy":[185],"deterioration":[187],"permeability.":[189]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}