{"id":"https://openalex.org/W2021598528","doi":"https://doi.org/10.1197/j.aem.2004.11.029","title":"Early Glycoprotein IIb/IIIa Inhibitor Use for Non-ST-segment Elevation Acute Coronary Syndrome: Patient Selection and Associated Treatment Patterns","display_name":"Early Glycoprotein IIb/IIIa Inhibitor Use for Non-ST-segment Elevation Acute Coronary Syndrome: Patient Selection and Associated Treatment Patterns","publication_year":2005,"publication_date":"2005-04-28","ids":{"openalex":"https://openalex.org/W2021598528","doi":"https://doi.org/10.1197/j.aem.2004.11.029","mag":"2021598528","pmid":"https://pubmed.ncbi.nlm.nih.gov/15863399"},"language":"en","primary_location":{"id":"doi:10.1197/j.aem.2004.11.029","doi":"https://doi.org/10.1197/j.aem.2004.11.029","is_oa":true,"landing_page_url":"https://doi.org/10.1197/j.aem.2004.11.029","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1197/j.aem.2004.11.029","source":{"id":"https://openalex.org/S171705774","display_name":"Academic Emergency Medicine","issn_l":"1069-6563","issn":["1069-6563","1553-2712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic Emergency Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1197/j.aem.2004.11.029","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111586231","display_name":"James W. Hoekstra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James W. Hoekstra","raw_affiliation_strings":["Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA. jhoekstr@wfubmc.edu","Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA. jhoekstr@wfubmc.edu","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"raw_affiliation_string":"Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC","institution_ids":["https://openalex.org/I4405269449"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055866744","display_name":"Matthew T. Roe","orcid":"https://orcid.org/0000-0002-4049-3458","observed_orcids":["https://orcid.org/0000-0002-4049-3458"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I4405286153","display_name":"Duke Clinical Research Institute","ror":"https://ror.org/019mv4g96","country_code":"US","type":"facility","lineage":["https://openalex.org/I170897317","https://openalex.org/I4405286153"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew T. Roe","raw_affiliation_strings":["Department of Emergency Medicine , Wake Forest Uni- versity Health Sciences (JWH , CM) , Winston-Salem , NC ;","Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine , Wake Forest Uni- versity Health Sciences (JWH , CM) , Winston-Salem , NC ;","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"raw_affiliation_string":"Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298","https://openalex.org/I4405286153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070062505","display_name":"Eric David Peterson","orcid":"https://orcid.org/0000-0002-5415-4721","observed_orcids":["https://orcid.org/0000-0002-5415-4721"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405286153","display_name":"Duke Clinical Research Institute","ror":"https://ror.org/019mv4g96","country_code":"US","type":"facility","lineage":["https://openalex.org/I170897317","https://openalex.org/I4405286153"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric D. Peterson","raw_affiliation_strings":["Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298","https://openalex.org/I4405286153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062737940","display_name":"Venu Menon","orcid":"https://orcid.org/0000-0003-4410-2677","observed_orcids":["https://orcid.org/0000-0003-4410-2677"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Venu Menon","raw_affiliation_strings":["Division of Cardiology, University of North Carolina, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of North Carolina, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068797105","display_name":"Jyotsna Mulgund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405286153","display_name":"Duke Clinical Research Institute","ror":"https://ror.org/019mv4g96","country_code":"US","type":"facility","lineage":["https://openalex.org/I170897317","https://openalex.org/I4405286153"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jyotsna Mulgund","raw_affiliation_strings":["Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298","https://openalex.org/I4405286153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048154042","display_name":"Charles V. Pollack","orcid":"https://orcid.org/0000-0002-1214-7881","observed_orcids":["https://orcid.org/0000-0002-1214-7881"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles V. Pollack","raw_affiliation_strings":["Department of Emergency Medicine, University of Pennsylvania, Philadelphia, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Pennsylvania, Philadelphia, PA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006531300","display_name":"Chadwick D. Miller","orcid":"https://orcid.org/0000-0002-4362-4409","observed_orcids":["https://orcid.org/0000-0002-4362-4409"]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chadwick Miller","raw_affiliation_strings":["Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC","institution_ids":["https://openalex.org/I4405269449"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028455924","display_name":"Theresa M. Palabrica","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270001","display_name":"Takeda Oncology (United States)","ror":"https://ror.org/05vm7p871","country_code":"US","type":"company","lineage":["https://openalex.org/I4405270001"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa Palabrica","raw_affiliation_strings":["Millennium Pharmaceuticals, Inc., Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Millennium Pharmaceuticals, Inc., Boston, MA","institution_ids":["https://openalex.org/I4405270001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060370891","display_name":"Robert A. Harrington","orcid":"https://orcid.org/0000-0001-5450-8676","observed_orcids":["https://orcid.org/0000-0001-5450-8676"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405286153","display_name":"Duke Clinical Research Institute","ror":"https://ror.org/019mv4g96","country_code":"US","type":"facility","lineage":["https://openalex.org/I170897317","https://openalex.org/I4405286153"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Harrington","raw_affiliation_strings":["Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298","https://openalex.org/I4405286153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074241426","display_name":"E. Magnus Ohman","orcid":"https://orcid.org/0000-0002-6249-4988","observed_orcids":["https://orcid.org/0000-0002-6249-4988"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Magnus Ohman","raw_affiliation_strings":["Division of Cardiology, University of North Carolina, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of North Carolina, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113082025","display_name":"W. Brian Gibler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Brian Gibler","raw_affiliation_strings":["Department of Emergency Medicine, University of Cincinnati School of Medicine, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Cincinnati School of Medicine, Cincinnati, OH","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"last","author":{"id":null,"display_name":"For the CRUSADE Investigators","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"For the CRUSADE Investigators","raw_affiliation_strings":["Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, NC","institution_ids":["https://openalex.org/I4405269449"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5111586231"],"corresponding_institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":4.3122,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.94336582,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"12","issue":"5","first_page":"431","last_page":"438"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.06650000065565109,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycoprotein-iib-iiia-inhibitors","display_name":"glycoprotein IIb/IIIa inhibitors","score":0.9919999837875366},{"id":"https://openalex.org/keywords/non-st-elevation-acute-coronary-syndrome","display_name":"non-ST-elevation acute coronary syndrome","score":0.9950000047683716},{"id":"https://openalex.org/keywords/early-antiplatelet-therapy","display_name":"early antiplatelet therapy","score":0.8379999995231628},{"id":"https://openalex.org/keywords/guideline-adherence","display_name":"guideline adherence","score":0.75},{"id":"https://openalex.org/keywords/patient-selection","display_name":"patient selection","score":0.8289999961853027},{"id":"https://openalex.org/keywords/treatment-patterns","display_name":"treatment patterns","score":0.5899999737739563},{"id":"https://openalex.org/keywords/cardiac-biomarkers","display_name":"cardiac biomarkers","score":0.5270000100135803},{"id":"https://openalex.org/keywords/st-segment-deviation","display_name":"ST-segment deviation","score":0.7749999761581421},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.796999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9616302251815796},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.7837083339691162},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6222385168075562},{"id":"https://openalex.org/C2778704086","wikidata":"https://www.wikidata.org/wiki/Q693058","display_name":"Chest pain","level":2,"score":0.5871194005012512},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.5008726119995117},{"id":"https://openalex.org/C2776291336","wikidata":"https://www.wikidata.org/wiki/Q7394928","display_name":"ST elevation","level":3,"score":0.47899314761161804},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4689576029777527},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.44863057136535645},{"id":"https://openalex.org/C2777260377","wikidata":"https://www.wikidata.org/wiki/Q2604639","display_name":"Coronary care unit","level":3,"score":0.4452562630176544},{"id":"https://openalex.org/C2771771","wikidata":"https://www.wikidata.org/wiki/Q6576883","display_name":"ST segment","level":3,"score":0.4232473373413086},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4216967225074768},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.26838940382003784},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002309","descriptor_name":"Cardiology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D002309","descriptor_name":"Cardiology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D002309","descriptor_name":"Cardiology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010043","descriptor_name":"Outcome and Process Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010043","descriptor_name":"Outcome and Process Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010043","descriptor_name":"Outcome and Process Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018579","descriptor_name":"Patient Selection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018579","descriptor_name":"Patient Selection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018579","descriptor_name":"Patient Selection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019039","descriptor_name":"Platelet Glycoprotein GPIIb-IIIa Complex","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019039","descriptor_name":"Platelet Glycoprotein GPIIb-IIIa Complex","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019039","descriptor_name":"Platelet Glycoprotein GPIIb-IIIa Complex","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1197/j.aem.2004.11.029","doi":"https://doi.org/10.1197/j.aem.2004.11.029","is_oa":true,"landing_page_url":"https://doi.org/10.1197/j.aem.2004.11.029","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1197/j.aem.2004.11.029","source":{"id":"https://openalex.org/S171705774","display_name":"Academic Emergency Medicine","issn_l":"1069-6563","issn":["1069-6563","1553-2712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic Emergency Medicine","raw_type":"journal-article"},{"id":"pmid:15863399","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15863399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic emergency medicine : official journal of the Society for Academic Emergency Medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1197/j.aem.2004.11.029","doi":"https://doi.org/10.1197/j.aem.2004.11.029","is_oa":true,"landing_page_url":"https://doi.org/10.1197/j.aem.2004.11.029","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1197/j.aem.2004.11.029","source":{"id":"https://openalex.org/S171705774","display_name":"Academic Emergency Medicine","issn_l":"1069-6563","issn":["1069-6563","1553-2712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic Emergency Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8100000023841858,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2021598528.pdf","grobid_xml":"https://content.openalex.org/works/W2021598528.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W979638655","https://openalex.org/W1591592548","https://openalex.org/W2030095927","https://openalex.org/W2034690624","https://openalex.org/W2048456880","https://openalex.org/W2059215195","https://openalex.org/W2111925599","https://openalex.org/W2125937777","https://openalex.org/W2127489984","https://openalex.org/W2149599987","https://openalex.org/W2149860264","https://openalex.org/W2316460201","https://openalex.org/W2327567334","https://openalex.org/W2338764889","https://openalex.org/W2769989850","https://openalex.org/W4237892021","https://openalex.org/W4256202725"],"related_works":["https://openalex.org/W2294399014","https://openalex.org/W2147095843","https://openalex.org/W2125937777","https://openalex.org/W2123354941","https://openalex.org/W1990651039","https://openalex.org/W2073888273","https://openalex.org/W2027704218","https://openalex.org/W2324275094","https://openalex.org/W2070621894","https://openalex.org/W2012168442"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1],"authors":[2],"analyzed":[3],"contemporary":[4],"use":[5,33,43],"of":[6,44,72,103,118,216,237],"glycoprotein":[7],"(GP)":[8],"IIb/IIIa":[9,31,39,108,122,156,192,200,225,240,249],"inhibitors":[10,109,123,241],"in":[11,124,130,138,230],"patients":[12,67,105,119,231],"with":[13,26,68,153,160,232,254],"non-ST-segment":[14],"elevation":[15],"acute":[16],"coronary":[17,132],"syndrome":[18],"(NSTE":[19],"ACS)":[20],"to":[21,97,143,176,188,206,258],"determine":[22],"patient":[23,59],"selection":[24],"patterns":[25],"early":[27,154,190,198,223,238],"(<24":[28],"hours)":[29],"GP":[30,38,107,121,155,191,199,224,239,248],"inhibitor":[32,40,157,193,201,226,250],"and":[34,42,63,76,135,235],"the":[35,53,125,131,139,148,213,259],"relationship":[36],"between":[37],"therapy":[41,202,227,251],"other":[45,208],"guidelines-recommended":[46,209],"therapies":[47],"for":[48,65,171],"NSTE":[49,233],"ACS.":[50],"METHODS:":[51],"Using":[52],"CRUSADE":[54],"Quality":[55],"Improvement":[56],"Initiative":[57],"database,":[58],"characteristics,":[60],"in-hospital":[61],"treatments,":[62],"outcomes":[64],"65,424":[66],"ischemic":[69,82],"chest":[70],"pain":[71],"<24":[73,110],"hours'":[74],"duration":[75],"either":[77],"positive":[78],"cardiac":[79,162,173],"markers":[80,163],"or":[81,164,182],"electrocardiographic":[83],"changes":[84],"were":[85,88,185,203],"analyzed.":[86],"Data":[87],"collected":[89],"from":[90,94],"443":[91],"U.S.":[92],"hospitals":[93],"January":[95],"2001":[96],"June":[98],"2003.":[99],"RESULTS:":[100],"Only":[101],"35%":[102],"eligible":[104],"received":[106,120,197],"hours":[111],"after":[112],"hospital":[113],"admission.":[114],"Approximately":[115],"one":[116,128,136],"third":[117,129,137],"emergency":[126],"department,":[127],"care":[133,146],"unit,":[134],"catheterization":[140],"laboratory.":[141],"Admission":[142],"a":[144],"cardiologist's":[145],"was":[147],"most":[149],"significant":[150],"associated":[151,253],"factor":[152],"use,":[158],"along":[159],"elevated":[161],"ST-segment":[165],"deviation.":[166],"Patients":[167,195],"at":[168],"high":[169],"risk":[170],"adverse":[172],"events":[174],"due":[175],"advanced":[177],"age,":[178],"congestive":[179],"heart":[180],"failure,":[181],"female":[183],"gender":[184],"less":[186],"likely":[187,205],"receive":[189,207],"therapy.":[194],"who":[196],"more":[204],"therapies.":[210],"CONCLUSIONS:":[211],"Despite":[212],"American":[214],"College":[215],"Cardiology/American":[217],"Heart":[218],"Association":[219],"(ACC/AHA)":[220],"guidelines":[221],"recommendations,":[222],"remains":[228],"underutilized":[229],"ACS":[234],"administration":[236],"is":[242,252],"directed":[243],"toward":[244],"lower-risk":[245],"patients.":[246],"Early":[247],"improved":[255],"overall":[256],"adherence":[257],"ACC/AHA":[260],"guidelines.":[261]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-06-24T00:00:00"}