{"id":"https://openalex.org/W2021577809","doi":"https://doi.org/10.1016/s0735-1097(01)01202-5","title":"Bradykinin stimulates the release of tissue plasminogen activator in human coronary circulation: effects of angiotensin-converting enzyme inhibitors","display_name":"Bradykinin stimulates the release of tissue plasminogen activator in human coronary circulation: effects of angiotensin-converting enzyme inhibitors","publication_year":2001,"publication_date":"2001-05-01","ids":{"openalex":"https://openalex.org/W2021577809","doi":"https://doi.org/10.1016/s0735-1097(01)01202-5","mag":"2021577809","pmid":"https://pubmed.ncbi.nlm.nih.gov/11345366"},"language":"en","primary_location":{"id":"doi:10.1016/s0735-1097(01)01202-5","doi":"https://doi.org/10.1016/s0735-1097(01)01202-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(01)01202-5","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109701012025/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0735109701012025/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082901285","display_name":"Kazuo Minai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo Minai","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Japan","First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Japan","institution_ids":["https://openalex.org/I160046202"]},{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080526180","display_name":"Tetsuya Matsumoto","orcid":"https://orcid.org/0000-0001-9722-7663","observed_orcids":["https://orcid.org/0000-0001-9722-7663"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tetsuya Matsumoto","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049492433","display_name":"Hajime Horie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hajime Horie","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081992612","display_name":"Naoto Ohira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Ohira","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroyuki Takashima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Takashima","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023734515","display_name":"Hiroshi Yokohama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Yokohama","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076066875","display_name":"Masahiko Kinoshita","orcid":"https://orcid.org/0000-0002-6716-6377","observed_orcids":["https://orcid.org/0000-0002-6716-6377"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiko Kinoshita","raw_affiliation_strings":["First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080526180"],"corresponding_institution_ids":["https://openalex.org/I160046202"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":5.0633,"has_fulltext":true,"cited_by_count":85,"citation_normalized_percentile":{"value":0.9600758,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"37","issue":"6","first_page":"1565","last_page":"1570"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12910","display_name":"Eicosanoids and Hypertension Pharmacology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bradykinin","display_name":"bradykinin","score":1.0},{"id":"https://openalex.org/keywords/tissue-plasminogen-activator","display_name":"tissue plasminogen activator","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9390000104904175},{"id":"https://openalex.org/keywords/enalapril","display_name":"enalapril","score":0.9950000047683716},{"id":"https://openalex.org/keywords/coronary-circulation","display_name":"coronary circulation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.871999979019165},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/coronary-blood-flow","display_name":"coronary blood flow","score":0.9139999747276306},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.6779999732971191},{"id":"https://openalex.org/keywords/atypical-chest-pain","display_name":"atypical chest pain","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2779591629","wikidata":"https://www.wikidata.org/wiki/Q24745328","display_name":"Bradykinin","level":3,"score":0.932902991771698},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7407703399658203},{"id":"https://openalex.org/C27016395","wikidata":"https://www.wikidata.org/wiki/Q128861","display_name":"Angiotensin-converting enzyme","level":3,"score":0.7254209518432617},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6801444292068481},{"id":"https://openalex.org/C2779611605","wikidata":"https://www.wikidata.org/wiki/Q288280","display_name":"ACE inhibitor","level":4,"score":0.6535323262214661},{"id":"https://openalex.org/C2775940317","wikidata":"https://www.wikidata.org/wiki/Q422185","display_name":"Enalapril","level":4,"score":0.627758264541626},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5725591778755188},{"id":"https://openalex.org/C2779679481","wikidata":"https://www.wikidata.org/wiki/Q13581432","display_name":"Plasminogen activator","level":2,"score":0.514707624912262},{"id":"https://openalex.org/C2776572282","wikidata":"https://www.wikidata.org/wiki/Q416351","display_name":"Tissue plasminogen activator","level":2,"score":0.5007154941558838},{"id":"https://openalex.org/C2780675426","wikidata":"https://www.wikidata.org/wiki/Q410485","display_name":"Plasminogen activator inhibitor-1","level":3,"score":0.4914509057998657},{"id":"https://openalex.org/C2776157398","wikidata":"https://www.wikidata.org/wiki/Q497232","display_name":"Coronary circulation","level":3,"score":0.43048563599586487},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.29948723316192627},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.07356241345405579},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000109","descriptor_name":"Acetylcholine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001920","descriptor_name":"Bradykinin","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001920","descriptor_name":"Bradykinin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004656","descriptor_name":"Enalapril","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005342","descriptor_name":"Fibrinolysis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005342","descriptor_name":"Fibrinolysis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010208","descriptor_name":"Papaverine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014665","descriptor_name":"Vasodilator Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015150","descriptor_name":"Echocardiography, Doppler","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/s0735-1097(01)01202-5","doi":"https://doi.org/10.1016/s0735-1097(01)01202-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(01)01202-5","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109701012025/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:11345366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11345366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Clinical Trial"},{"id":"pmh:oai:irdb.nii.ac.jp:00998:0002407107","doi":null,"is_oa":true,"landing_page_url":"https://shiga-med.repo.nii.ac.jp/records/1266","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"other"},{"id":"mag:2303994903","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000355102","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1016/s0735-1097(01)01202-5","doi":"https://doi.org/10.1016/s0735-1097(01)01202-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0735-1097(01)01202-5","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109701012025/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2021577809.pdf","grobid_xml":"https://content.openalex.org/works/W2021577809.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W62127090","https://openalex.org/W146966810","https://openalex.org/W1964962715","https://openalex.org/W1968319785","https://openalex.org/W1968727207","https://openalex.org/W1976057876","https://openalex.org/W1979640628","https://openalex.org/W1980000060","https://openalex.org/W1981594756","https://openalex.org/W1991977311","https://openalex.org/W1992053233","https://openalex.org/W1995479866","https://openalex.org/W1996873499","https://openalex.org/W2002624460","https://openalex.org/W2024991598","https://openalex.org/W2033307460","https://openalex.org/W2039831544","https://openalex.org/W2044038692","https://openalex.org/W2048512830","https://openalex.org/W2074384719","https://openalex.org/W2076500453","https://openalex.org/W2076907458","https://openalex.org/W2141019187","https://openalex.org/W2312388685","https://openalex.org/W2400762994","https://openalex.org/W2401761232","https://openalex.org/W2414339591","https://openalex.org/W2617392052"],"related_works":["https://openalex.org/W2086811058","https://openalex.org/W2414339591","https://openalex.org/W2007129904","https://openalex.org/W4212818207","https://openalex.org/W2022321345","https://openalex.org/W2141019187","https://openalex.org/W1991092240","https://openalex.org/W7096570096","https://openalex.org/W2074384719","https://openalex.org/W7101072677"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}