{"id":"https://openalex.org/W2021473997","doi":"https://doi.org/10.1007/s11240-015-0773-8","title":"Metabolic alterations and distribution of five-carbon precursors in jasmonic acid-elicited Catharanthus roseus cell suspension cultures","display_name":"Metabolic alterations and distribution of five-carbon precursors in jasmonic acid-elicited Catharanthus roseus cell suspension cultures","publication_year":2015,"publication_date":"2015-04-17","ids":{"openalex":"https://openalex.org/W2021473997","doi":"https://doi.org/10.1007/s11240-015-0773-8","mag":"2021473997"},"language":"en","primary_location":{"id":"doi:10.1007/s11240-015-0773-8","doi":"https://doi.org/10.1007/s11240-015-0773-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11240-015-0773-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11240-015-0773-8.pdf","source":{"id":"https://openalex.org/S32261165","display_name":"Plant Cell Tissue and Organ Culture (PCTOC)","issn_l":"0167-6857","issn":["0167-6857","1573-5044"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Cell, Tissue and Organ Culture (PCTOC)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11240-015-0773-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042067593","display_name":"Mohd Zuwairi Saiman","orcid":"https://orcid.org/0000-0002-9487-5742","observed_orcids":["https://orcid.org/0000-0002-9487-5742"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]},{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY","NL"],"is_corresponding":false,"raw_author_name":"Mohd Zuwairi Saiman","raw_affiliation_strings":["Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia","Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032325619","display_name":"Natali Rianika Mustafa","orcid":"https://orcid.org/0000-0001-9780-1661","observed_orcids":["https://orcid.org/0000-0001-9780-1661"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Natali Rianika Mustafa","raw_affiliation_strings":["ExPlant Technologies B.V., Galileiweg 8, 2333 BD, Leiden, The Netherlands","Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ExPlant Technologies B.V., Galileiweg 8, 2333 BD, Leiden, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023713378","display_name":"Young Hae Choi","orcid":"https://orcid.org/0000-0003-1484-1700","observed_orcids":["https://orcid.org/0000-0003-1484-1700"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Young Hae Choi","raw_affiliation_strings":["Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032001335","display_name":"Robert Verpoorte","orcid":"https://orcid.org/0000-0001-6180-1424","observed_orcids":["https://orcid.org/0000-0001-6180-1424"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Robert Verpoorte","raw_affiliation_strings":["Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065133718","display_name":"Anna Elisabeth Schulte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anna Elisabeth Schulte","raw_affiliation_strings":["ExPlant Technologies B.V., Galileiweg 8, 2333 BD, Leiden, The Netherlands","Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ExPlant Technologies B.V., Galileiweg 8, 2333 BD, Leiden, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5032325619"],"corresponding_institution_ids":["https://openalex.org/I121797337"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":3.1858,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.90097991,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"122","issue":"2","first_page":"351","last_page":"362"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.5166000127792358,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.5166000127792358,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.48190000653266907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/catharanthus-roseus","display_name":"Catharanthus roseus","score":0.996999979019165},{"id":"https://openalex.org/keywords/monoterpene-indole-alkaloids","display_name":"monoterpene indole alkaloids","score":0.9559999704360962},{"id":"https://openalex.org/keywords/methylerythritol-phosphate-pathway","display_name":"methylerythritol phosphate pathway","score":0.8730000257492065},{"id":"https://openalex.org/keywords/carotenoids","display_name":"carotenoids","score":0.7400000095367432},{"id":"https://openalex.org/keywords/phytosterols","display_name":"phytosterols","score":0.9919999837875366},{"id":"https://openalex.org/keywords/terpenoid-biosynthesis","display_name":"terpenoid biosynthesis","score":0.8399999737739563},{"id":"https://openalex.org/keywords/strictosidine","display_name":"strictosidine","score":0.8199999928474426},{"id":"https://openalex.org/keywords/nmr-based-metabolomics","display_name":"NMR metabolomics","score":0.7440000176429749},{"id":"https://openalex.org/keywords/cell-suspension-culture","display_name":"cell suspension culture","score":0.7039999961853027},{"id":"https://openalex.org/keywords/metabolic-engineering","display_name":"metabolic engineering","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C206103511","wikidata":"https://www.wikidata.org/wiki/Q426694","display_name":"Terpenoid","level":2,"score":0.8925675749778748},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6386242508888245},{"id":"https://openalex.org/C2779906556","wikidata":"https://www.wikidata.org/wiki/Q161093","display_name":"Catharanthus roseus","level":2,"score":0.6106858849525452},{"id":"https://openalex.org/C2779080361","wikidata":"https://www.wikidata.org/wiki/Q415311","display_name":"Jasmonic acid","level":3,"score":0.605114221572876},{"id":"https://openalex.org/C28781525","wikidata":"https://www.wikidata.org/wiki/Q191907","display_name":"Carotenoid","level":2,"score":0.5742114782333374},{"id":"https://openalex.org/C192989942","wikidata":"https://www.wikidata.org/wiki/Q68685","display_name":"Metabolic pathway","level":3,"score":0.4964454770088196},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4566558599472046},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4239118695259094},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3981790542602539},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/s11240-015-0773-8","doi":"https://doi.org/10.1007/s11240-015-0773-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11240-015-0773-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11240-015-0773-8.pdf","source":{"id":"https://openalex.org/S32261165","display_name":"Plant Cell Tissue and Organ Culture (PCTOC)","issn_l":"0167-6857","issn":["0167-6857","1573-5044"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Cell, Tissue and Organ Culture (PCTOC)","raw_type":"journal-article"},{"id":"pmh:oai:alma.31UKB_LEU:9940743408102711","doi":null,"is_oa":true,"landing_page_url":"https://scholarlypublications.universiteitleiden.nl/handle/1887/3192168","pdf_url":"https://scholarlypublications.universiteitleiden.nl/download/1887/3192168/1?col=81522199440002711","source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plant Cell, Tissue and Organ Culture, Vol. 122, p. 351-362","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:scholarlypublications.universiteitleiden.nl:item_3192168","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1887/3192168","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plant Cell, Tissue and Organ Culture","raw_type":"Article / Letter to editor"},{"id":"pmh:ul:oai:scholarlypublications.universiteitleiden.nl:item_3192168","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1887/3192168","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plant Cell, Tissue and Organ Culture, 122, 351 - 362","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1007/s11240-015-0773-8","doi":"https://doi.org/10.1007/s11240-015-0773-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11240-015-0773-8","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11240-015-0773-8.pdf","source":{"id":"https://openalex.org/S32261165","display_name":"Plant Cell Tissue and Organ Culture (PCTOC)","issn_l":"0167-6857","issn":["0167-6857","1573-5044"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Cell, Tissue and Organ Culture (PCTOC)","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320322604","display_name":"Universiti Malaya","ror":"https://ror.org/00rzspn62"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2021473997.pdf","grobid_xml":"https://content.openalex.org/works/W2021473997.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W40033085","https://openalex.org/W41912685","https://openalex.org/W94301936","https://openalex.org/W139039044","https://openalex.org/W243878342","https://openalex.org/W592959149","https://openalex.org/W1975492718","https://openalex.org/W1983830548","https://openalex.org/W1984046418","https://openalex.org/W1988609913","https://openalex.org/W1993062033","https://openalex.org/W1994766005","https://openalex.org/W1996009984","https://openalex.org/W2000293240","https://openalex.org/W2008289033","https://openalex.org/W2016735147","https://openalex.org/W2019064344","https://openalex.org/W2030917828","https://openalex.org/W2033134788","https://openalex.org/W2036494512","https://openalex.org/W2039982119","https://openalex.org/W2055605628","https://openalex.org/W2070026398","https://openalex.org/W2073461406","https://openalex.org/W2075514111","https://openalex.org/W2075791637","https://openalex.org/W2077545872","https://openalex.org/W2078929165","https://openalex.org/W2085534319","https://openalex.org/W2085685413","https://openalex.org/W2085917889","https://openalex.org/W2086967972","https://openalex.org/W2089210920","https://openalex.org/W2089810543","https://openalex.org/W2097693284","https://openalex.org/W2117856189","https://openalex.org/W2122716789","https://openalex.org/W2129702544","https://openalex.org/W2131219362","https://openalex.org/W2133092903","https://openalex.org/W2145741655","https://openalex.org/W2146679196","https://openalex.org/W2159181928","https://openalex.org/W2159356563","https://openalex.org/W2186203974","https://openalex.org/W2584766397","https://openalex.org/W2594706266"],"related_works":["https://openalex.org/W2738180146","https://openalex.org/W2000293240","https://openalex.org/W2734422929","https://openalex.org/W2038572200","https://openalex.org/W2070026398","https://openalex.org/W2001433477","https://openalex.org/W2080212968","https://openalex.org/W1973146017","https://openalex.org/W3127883803","https://openalex.org/W2016735147"],"abstract_inverted_index":{"In":[0],"Catharanthus":[1],"roseus":[2,102,315],"cell":[3,97,316],"cultures,":[4],"the":[5,11,44,50,53,71,81,86,96,110,153,168,179,185,190,210,227,240],"terpenoid":[6,15,32,73,115,181,242,289],"moiety":[7],"is":[8,27,62,187,220],"considered":[9],"as":[10],"limiting":[12],"factor":[13],"in":[14,25,167,266,287,303,308],"indole":[16],"alkaloid":[17],"(TIA)":[18],"production.":[19],"The":[20,131],"pathway":[21],"of":[22,55,67,80,88,100,113,175,193,213,226,236,251,268,284],"terpenoidal":[23],"precursors":[24,69,177,238,286],"TIA":[26,36,56,121,136,157,214],"strongly":[28],"linked":[29],"with":[30,105,263],"other":[31],"pathways,":[33,291],"suggesting":[34],"that":[35,135,209],"production":[37,57,212],"might":[38],"be":[39],"limited":[40],"by":[41,58,223],"competition":[42],"for":[43,297],"five-carbon":[45],"(C5)":[46],"precursors.":[47],"This":[48,207,274],"raises":[49],"question":[51],"whether":[52],"stimulation":[54],"certain":[59],"signal":[60,91],"molecules":[61],"due":[63,232],"to":[64,76,152,178,233,300,310],"a":[65,77,89,234,249,294,304],"redistribution":[66,235],"C5":[68,94,165,176,237,285],"between":[70,239,256],"associated":[72,241],"pathways":[74,116],"and/or":[75],"total":[78],"increase":[79,225],"precursor":[82,228],"availability.":[83],"To":[84],"investigate":[85],"effect":[87],"TIA-increasing":[90],"molecule":[92],"on":[93,120],"distribution,":[95],"suspension":[98],"cultures":[99],"C.":[101,314],"were":[103,117],"elicited":[104,203],"jasmonic":[106],"acid":[107],"(JA)":[108],"and":[109,127,137,158,172,204,215,253,258,272,282],"metabolic":[111,277],"changes":[112,265],"different":[114,288],"evaluated":[118],"targeting":[119],"(monoterpenoid;":[122],"C10),":[123],"carotenoids":[124],"(tetraterpenoid;":[125],"C40),":[126],"phytosterols":[128,186],"(triterpenoid;":[129],"C30).":[130],"chromatographic":[132],"analyses":[133],"showed":[134,248],"carotenoid":[138,159,216],"levels":[139,147,267],"almost":[140],"doubled":[141],"upon":[142,217,279],"JA":[143,218,280],"elicitation,":[144],"while":[145],"phytosterol":[146],"remained":[148],"constant":[149],"if":[150],"compared":[151],"controls.":[154],"Apparently,":[155],"both":[156],"routes":[160],"benefit":[161],"from":[162],"an":[163,224],"increased":[164,211],"flow":[166],"methyl-erythritol":[169],"phosphate":[170],"pathway,":[171],"potential":[173],"export":[174],"cytosolic":[180],"routes,":[182],"e.g.,":[183],"towards":[184],"minimal.":[188],"However,":[189],"relative":[191],"composition":[192],"individual":[194],"compounds":[195],"within":[196],"each":[197],"group":[198],"remains":[199],"similar":[200],"when":[201],"comparing":[202],"control":[205,254],"cells.":[206],"suggests":[208],"elicitation":[219,281],"predominantly":[221],"caused":[222],"availability":[229],"rather":[230],"than":[231],"pathways.":[243],"Furthermore,":[244],"NMR-based":[245],"metabolomics":[246],"analysis":[247],"discrimination":[250],"JA-elicited":[252],"cells":[255],"24":[257],"72":[259],"h":[260],"after":[261],"treatments":[262],"significant":[264],"strictosidine,":[269],"malic":[270],"acid,":[271],"sucrose.":[273],"study":[275],"portrays":[276],"alterations":[278],"channeling":[283],"biosynthetic":[290,306],"which":[292],"provides":[293],"knowledge":[295],"platform":[296],"developing":[298],"strategies":[299],"engineer":[301],"fluxes":[302],"complex":[305],"network":[307],"order":[309],"obtain":[311],"high":[312],"TIA-producing":[313],"lines.":[317]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
