{"id":"https://openalex.org/W2021187094","doi":"https://doi.org/10.1007/bf00234219","title":"Nonparallel changes in brain monoamines of pyridoxine-deficient growing rats","display_name":"Nonparallel changes in brain monoamines of pyridoxine-deficient growing rats","publication_year":1976,"publication_date":"1976-11-01","ids":{"openalex":"https://openalex.org/W2021187094","doi":"https://doi.org/10.1007/bf00234219","mag":"2021187094","pmid":"https://pubmed.ncbi.nlm.nih.gov/1001386"},"language":"en","primary_location":{"id":"doi:10.1007/bf00234219","doi":"https://doi.org/10.1007/bf00234219","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00234219","pdf_url":null,"source":{"id":"https://openalex.org/S45281609","display_name":"Experimental Brain Research","issn_l":"0014-4819","issn":["0014-4819","1432-1106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111525925","display_name":"K. Dakshinamurti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"K. Dakshinamurti","raw_affiliation_strings":["Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]},{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038187037","display_name":"W.D. LeBlancq","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W.D. LeBlancq","raw_affiliation_strings":["Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]},{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048794918","display_name":"R. Herchl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. Herchl","raw_affiliation_strings":["Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]},{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064780943","display_name":"Viktor Havlicek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"V. Havlicek","raw_affiliation_strings":["Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, R3E OW3, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]},{"raw_affiliation_string":"Departments of Biochemistry and Physiology, University of Manitoba, Winnipeg, Canada","institution_ids":["https://openalex.org/I46247651"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I46247651"],"apc_list":{"value":2590,"currency":"USD","value_usd":2590},"apc_paid":null,"fwci":0.4451,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.61741233,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"26","issue":"4","first_page":"355","last_page":"66"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.36500000953674316,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.36500000953674316,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.3571999967098236,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.12960000336170197,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-b6-deficiency","display_name":"vitamin B6 deficiency","score":0.9990000128746033},{"id":"https://openalex.org/keywords/brain-monoamines","display_name":"brain monoamines","score":0.781000018119812},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9449999928474426},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":1.0},{"id":"https://openalex.org/keywords/tryptophan-hydroxylase","display_name":"tryptophan hydroxylase","score":0.8889999985694885},{"id":"https://openalex.org/keywords/pyridoxal-5-phosphate","display_name":"pyridoxal phosphate","score":0.9010000228881836},{"id":"https://openalex.org/keywords/tryptophan-metabolism","display_name":"tryptophan metabolism","score":0.7369999885559082},{"id":"https://openalex.org/keywords/5-hydroxyindoleacetic-acid","display_name":"5-hydroxyindoleacetic acid","score":0.9309999942779541},{"id":"https://openalex.org/keywords/growing-rats","display_name":"growing rats","score":0.7960000038146973}],"concepts":[{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.8116633296012878},{"id":"https://openalex.org/C2776514930","wikidata":"https://www.wikidata.org/wiki/Q423746","display_name":"Pyridoxine","level":2,"score":0.8107041120529175},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6577608585357666},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.6554990410804749},{"id":"https://openalex.org/C2909176517","wikidata":"https://www.wikidata.org/wiki/Q205130","display_name":"Pyridoxine Deficiency","level":3,"score":0.648404598236084},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6322439908981323},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6291831731796265},{"id":"https://openalex.org/C187714386","wikidata":"https://www.wikidata.org/wiki/Q420225","display_name":"Monoamine neurotransmitter","level":4,"score":0.6248286366462708},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.6160314083099365},{"id":"https://openalex.org/C2779164789","wikidata":"https://www.wikidata.org/wiki/Q238532","display_name":"5-Hydroxyindoleacetic acid","level":4,"score":0.6153436303138733},{"id":"https://openalex.org/C58824617","wikidata":"https://www.wikidata.org/wiki/Q421186","display_name":"Aromatic L-amino acid decarboxylase","level":3,"score":0.5881902575492859},{"id":"https://openalex.org/C2780595602","wikidata":"https://www.wikidata.org/wiki/Q898436","display_name":"Decarboxylation","level":3,"score":0.5778089761734009},{"id":"https://openalex.org/C2775951788","wikidata":"https://www.wikidata.org/wiki/Q418293","display_name":"Tryptophan hydroxylase","level":5,"score":0.500633955001831},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.4514904022216797},{"id":"https://openalex.org/C2777440324","wikidata":"https://www.wikidata.org/wiki/Q4161984","display_name":"Dihydroxyphenylalanine","level":3,"score":0.4235432744026184},{"id":"https://openalex.org/C2779399491","wikidata":"https://www.wikidata.org/wiki/Q238544","display_name":"5-Hydroxytryptophan","level":4,"score":0.41592666506767273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29716333746910095},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.22745022177696228},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1945161521434784},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17239925265312195},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.1564021110534668},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006897","descriptor_name":"Hydroxyindoleacetic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010293","descriptor_name":"Pargyline","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011339","descriptor_name":"Probenecid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011736","descriptor_name":"Pyridoxine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014365","descriptor_name":"Tryptophan Hydroxylase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D026681","descriptor_name":"Vitamin B 6 Deficiency","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00234219","doi":"https://doi.org/10.1007/bf00234219","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00234219","pdf_url":null,"source":{"id":"https://openalex.org/S45281609","display_name":"Experimental Brain Research","issn_l":"0014-4819","issn":["0014-4819","1432-1106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Brain Research","raw_type":"journal-article"},{"id":"pmid:1001386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1001386","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W16931939","https://openalex.org/W98238708","https://openalex.org/W216492396","https://openalex.org/W1462472419","https://openalex.org/W1467017054","https://openalex.org/W1497427077","https://openalex.org/W1571821264","https://openalex.org/W1584641294","https://openalex.org/W1831917936","https://openalex.org/W1841783765","https://openalex.org/W1850207368","https://openalex.org/W1966199998","https://openalex.org/W1969291259","https://openalex.org/W1970609319","https://openalex.org/W1978593419","https://openalex.org/W1987416112","https://openalex.org/W1990784490","https://openalex.org/W1995837298","https://openalex.org/W2003092157","https://openalex.org/W2004895078","https://openalex.org/W2005290213","https://openalex.org/W2005377477","https://openalex.org/W2010740532","https://openalex.org/W2013222020","https://openalex.org/W2020059734","https://openalex.org/W2025629975","https://openalex.org/W2029295823","https://openalex.org/W2031809795","https://openalex.org/W2035805587","https://openalex.org/W2044610512","https://openalex.org/W2059144779","https://openalex.org/W2062829451","https://openalex.org/W2065421099","https://openalex.org/W2079814518","https://openalex.org/W2090097095","https://openalex.org/W2092299253","https://openalex.org/W2139732917","https://openalex.org/W2172291712","https://openalex.org/W2173223440","https://openalex.org/W2256615984","https://openalex.org/W2274148752","https://openalex.org/W2337339762","https://openalex.org/W2403552658","https://openalex.org/W2429619569","https://openalex.org/W2525550930","https://openalex.org/W2552318961","https://openalex.org/W4290106307"],"related_works":["https://openalex.org/W2129835686","https://openalex.org/W2067098054","https://openalex.org/W2061335326","https://openalex.org/W2341321049","https://openalex.org/W2402311796","https://openalex.org/W2402031189","https://openalex.org/W2011481175","https://openalex.org/W7095761997","https://openalex.org/W2041813481","https://openalex.org/W2409838274"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}