{"id":"https://openalex.org/W2021168030","doi":"https://doi.org/10.1016/0009-2797(82)90091-6","title":"Alkaline opening of imidazole ring of 7-methylguanosine. 1. Analysis of the resulting pyrimidine derivatives","display_name":"Alkaline opening of imidazole ring of 7-methylguanosine. 1. Analysis of the resulting pyrimidine derivatives","publication_year":1982,"publication_date":"1982-08-01","ids":{"openalex":"https://openalex.org/W2021168030","doi":"https://doi.org/10.1016/0009-2797(82)90091-6","mag":"2021168030","pmid":"https://pubmed.ncbi.nlm.nih.gov/7049418"},"language":"en","primary_location":{"id":"doi:10.1016/0009-2797(82)90091-6","doi":"https://doi.org/10.1016/0009-2797(82)90091-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0009-2797(82)90091-6","pdf_url":"https://www.sciencedirect.com/science/article/pii/0009279782900916","source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/0009279782900916","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014441979","display_name":"Christopher J. Chetsanga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130704","display_name":"University of Michigan\u2013Dearborn","ror":"https://ror.org/035wtm547","country_code":"US","type":"education","lineage":["https://openalex.org/I4210130704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.J. Chetsanga","raw_affiliation_strings":["Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A","institution_ids":["https://openalex.org/I4210130704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077008874","display_name":"B. Bearie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130704","display_name":"University of Michigan\u2013Dearborn","ror":"https://ror.org/035wtm547","country_code":"US","type":"education","lineage":["https://openalex.org/I4210130704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Bearie","raw_affiliation_strings":["Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A","institution_ids":["https://openalex.org/I4210130704"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013459145","display_name":"Christopher A. Makaroff","orcid":"https://orcid.org/0000-0001-6237-1868","observed_orcids":["https://orcid.org/0000-0001-6237-1868"]},"institutions":[{"id":"https://openalex.org/I4210130704","display_name":"University of Michigan\u2013Dearborn","ror":"https://ror.org/035wtm547","country_code":"US","type":"education","lineage":["https://openalex.org/I4210130704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Makaroff","raw_affiliation_strings":["Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Program, Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, MI 48128 U.S.A","institution_ids":["https://openalex.org/I4210130704"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210130704"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":0.8502,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.69089547,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"41","issue":"2","first_page":"217","last_page":"233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9473000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9473000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/7-methylguanosine","display_name":"7-methylguanosine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/imidazole-ring-opening","display_name":"imidazole ring opening","score":0.8539999723434448},{"id":"https://openalex.org/keywords/pyrimidine-derivatives","display_name":"pyrimidine derivatives","score":0.8230000138282776},{"id":"https://openalex.org/keywords/7-methylguanine","display_name":"7-methylguanine","score":0.8970000147819519},{"id":"https://openalex.org/keywords/formylation","display_name":"formylation","score":0.7300000190734863},{"id":"https://openalex.org/keywords/deformylation","display_name":"deformylation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/formamidopyrimidine-dna-glycosylase","display_name":"formamidopyrimidine-DNA glycosylase","score":0.8320000171661377},{"id":"https://openalex.org/keywords/dna-glycosylase","display_name":"DNA glycosylase","score":0.5070000290870667},{"id":"https://openalex.org/keywords/alkali-treatment","display_name":"alkali treatment","score":0.3959999978542328},{"id":"https://openalex.org/keywords/chemical-modification-of-dna","display_name":"chemical modification of DNA","score":0.4000000059604645}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8597352504730225},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.7310343980789185},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.7058858275413513},{"id":"https://openalex.org/C2775986502","wikidata":"https://www.wikidata.org/wiki/Q420466","display_name":"Ammonium formate","level":3,"score":0.6567831635475159},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6287375688552856},{"id":"https://openalex.org/C2779607525","wikidata":"https://www.wikidata.org/wiki/Q14982","display_name":"Methanol","level":2,"score":0.5310842394828796},{"id":"https://openalex.org/C2779321679","wikidata":"https://www.wikidata.org/wiki/Q207722","display_name":"Pyrimidine","level":2,"score":0.4927425682544708},{"id":"https://openalex.org/C51724486","wikidata":"https://www.wikidata.org/wiki/Q908955","display_name":"Column chromatography","level":2,"score":0.48160359263420105},{"id":"https://openalex.org/C2780874372","wikidata":"https://www.wikidata.org/wiki/Q328692","display_name":"Imidazole","level":2,"score":0.4645414650440216},{"id":"https://openalex.org/C2780178953","wikidata":"https://www.wikidata.org/wiki/Q2001841","display_name":"Formate","level":3,"score":0.4468843340873718},{"id":"https://openalex.org/C163994747","wikidata":"https://www.wikidata.org/wiki/Q2916358","display_name":"Sephadex","level":3,"score":0.4446413218975067},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2243126928806305},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.17049461603164673},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.09198912978172302},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D006146","descriptor_name":"Guanidines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008760","descriptor_name":"Methylguanidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009699","descriptor_name":"N-Glycosyl Hydrolases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043382","descriptor_name":"DNA-Formamidopyrimidine Glycosylase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/0009-2797(82)90091-6","doi":"https://doi.org/10.1016/0009-2797(82)90091-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0009-2797(82)90091-6","pdf_url":"https://www.sciencedirect.com/science/article/pii/0009279782900916","source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},{"id":"pmid:7049418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7049418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-biological interactions","raw_type":"Journal Article"},{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/23912","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/23912","pdf_url":"https://hdl.handle.net/2027.42/23912","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/0009-2797(82)90091-6","doi":"https://doi.org/10.1016/0009-2797(82)90091-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0009-2797(82)90091-6","pdf_url":"https://www.sciencedirect.com/science/article/pii/0009279782900916","source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309652","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2021168030.pdf","grobid_xml":"https://content.openalex.org/works/W2021168030.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W154012288","https://openalex.org/W999705638","https://openalex.org/W1259363667","https://openalex.org/W1966411006","https://openalex.org/W1966456746","https://openalex.org/W1967683999","https://openalex.org/W1989737739","https://openalex.org/W1998226230","https://openalex.org/W2037320922","https://openalex.org/W2050276607","https://openalex.org/W2069928999","https://openalex.org/W2070552453","https://openalex.org/W2074762638","https://openalex.org/W2092862428","https://openalex.org/W2116390732","https://openalex.org/W2123475461","https://openalex.org/W2141938404","https://openalex.org/W2233447257","https://openalex.org/W2318801214","https://openalex.org/W2332608159","https://openalex.org/W6641997863","https://openalex.org/W6673850034","https://openalex.org/W6677306141","https://openalex.org/W6680927847"],"related_works":["https://openalex.org/W7101081531","https://openalex.org/W2092862428","https://openalex.org/W1996331187","https://openalex.org/W2034823509","https://openalex.org/W2037050415","https://openalex.org/W2112078344","https://openalex.org/W1991597416","https://openalex.org/W2014613267","https://openalex.org/W2054393067","https://openalex.org/W2018148777"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}