{"id":"https://openalex.org/W2021058503","doi":"https://doi.org/10.1016/0167-4781(83)90109-4","title":"RNA synthesis by villus and crypt cell nuclei of rat intestinal mucosa","display_name":"RNA synthesis by villus and crypt cell nuclei of rat intestinal mucosa","publication_year":1983,"publication_date":"1983-04-01","ids":{"openalex":"https://openalex.org/W2021058503","doi":"https://doi.org/10.1016/0167-4781(83)90109-4","mag":"2021058503","pmid":"https://pubmed.ncbi.nlm.nih.gov/6830810"},"language":"en","primary_location":{"id":"doi:10.1016/0167-4781(83)90109-4","doi":"https://doi.org/10.1016/0167-4781(83)90109-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4781(83)90109-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210212269","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","issn_l":"0167-4781","issn":["0167-4781","1879-2634"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011495169","display_name":"Adrienne Bronstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.D. Bronstein","raw_affiliation_strings":["Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011889522","display_name":"Neal S. LeLeiko","orcid":"https://orcid.org/0000-0001-7699-1400","observed_orcids":["https://orcid.org/0000-0001-7699-1400"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N.S. Leleiko","raw_affiliation_strings":["Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110394056","display_name":"Hamish Nisbet Munro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"H.N. Munro","raw_affiliation_strings":["Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA U.S.A","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111 U.S.A","institution_ids":["https://openalex.org/I121934306"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110394056"],"corresponding_institution_ids":["https://openalex.org/I121934306","https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":0.5234,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.65388609,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"739","issue":"3","first_page":"334","last_page":"343"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.013700000010430813,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-synthesis","display_name":"RNA synthesis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/intestinal-mucosa","display_name":"intestinal mucosa","score":0.9010000228881836},{"id":"https://openalex.org/keywords/villus-cells","display_name":"villus cells","score":0.925000011920929},{"id":"https://openalex.org/keywords/crypt-cells","display_name":"crypt cells","score":0.9819999933242798},{"id":"https://openalex.org/keywords/nondividing-cells","display_name":"non-dividing cells","score":0.8180000185966492},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.8769999742507935},{"id":"https://openalex.org/keywords/thymidine-kinase","display_name":"thymidine kinase","score":0.9919999837875366},{"id":"https://openalex.org/keywords/subcellular-fractionation","display_name":"subcellular fractionation","score":0.621999979019165},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C66090201","wikidata":"https://www.wikidata.org/wiki/Q15995009","display_name":"Crypt","level":2,"score":0.9328187108039856},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6806000471115112},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5702518820762634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49165230989456177},{"id":"https://openalex.org/C2777108182","wikidata":"https://www.wikidata.org/wiki/Q422464","display_name":"Thymidine","level":3,"score":0.4830789864063263},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44788146018981934},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4378892183303833},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.4362730085849762},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4171752333641052},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4151308536529541},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3107815980911255},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14708423614501953},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.12767446041107178},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002469","descriptor_name":"Cell Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0167-4781(83)90109-4","doi":"https://doi.org/10.1016/0167-4781(83)90109-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4781(83)90109-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210212269","display_name":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","issn_l":"0167-4781","issn":["0167-4781","1879-2634"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","raw_type":"journal-article"},{"id":"pmid:6830810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6830810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W64775550","https://openalex.org/W111057963","https://openalex.org/W225487714","https://openalex.org/W1013743588","https://openalex.org/W1156871399","https://openalex.org/W1428921743","https://openalex.org/W1560026473","https://openalex.org/W1672352349","https://openalex.org/W1775749144","https://openalex.org/W1837697743","https://openalex.org/W1845085723","https://openalex.org/W1906197854","https://openalex.org/W1915644623","https://openalex.org/W1971177469","https://openalex.org/W1972398050","https://openalex.org/W1982322136","https://openalex.org/W1984381775","https://openalex.org/W1987813562","https://openalex.org/W1989968796","https://openalex.org/W1992920866","https://openalex.org/W1995201350","https://openalex.org/W1999736909","https://openalex.org/W2000942140","https://openalex.org/W2003150784","https://openalex.org/W2008257286","https://openalex.org/W2008904713","https://openalex.org/W2009504999","https://openalex.org/W2014588512","https://openalex.org/W2014751751","https://openalex.org/W2015151228","https://openalex.org/W2030710287","https://openalex.org/W2033829859","https://openalex.org/W2042750055","https://openalex.org/W2067669375","https://openalex.org/W2070538099","https://openalex.org/W2073871003","https://openalex.org/W2086373321","https://openalex.org/W2111319305","https://openalex.org/W2418959378","https://openalex.org/W2419286029"],"related_works":["https://openalex.org/W1987813562","https://openalex.org/W2062453298","https://openalex.org/W2076256774","https://openalex.org/W2067475536","https://openalex.org/W111057963","https://openalex.org/W1915644623","https://openalex.org/W2307081969","https://openalex.org/W2142759605","https://openalex.org/W2044392326","https://openalex.org/W2079248125"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}