{"id":"https://openalex.org/W2020853520","doi":"https://doi.org/10.1016/0027-5107(82)90207-x","title":"The chemical activation of non-mutagenic nitrated polycyclic aromatic hydrocarbons to mutagens","display_name":"The chemical activation of non-mutagenic nitrated polycyclic aromatic hydrocarbons to mutagens","publication_year":1982,"publication_date":"1982-02-01","ids":{"openalex":"https://openalex.org/W2020853520","doi":"https://doi.org/10.1016/0027-5107(82)90207-x","mag":"2020853520","pmid":"https://pubmed.ncbi.nlm.nih.gov/7045649"},"language":"en","primary_location":{"id":"doi:10.1016/0027-5107(82)90207-x","doi":"https://doi.org/10.1016/0027-5107(82)90207-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(82)90207-x","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091543594","display_name":"George E. Karpinsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132870","display_name":"Xerox (United States)","ror":"https://ror.org/03jwzwq24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210132870"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George E. Karpinsky","raw_affiliation_strings":["Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A","institution_ids":["https://openalex.org/I4210132870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084798997","display_name":"Elena C. McCoy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132870","display_name":"Xerox (United States)","ror":"https://ror.org/03jwzwq24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210132870"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elena C. McCoy","raw_affiliation_strings":["Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A","institution_ids":["https://openalex.org/I4210132870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073709590","display_name":"Herbert S. Rosenkranz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132870","display_name":"Xerox (United States)","ror":"https://ror.org/03jwzwq24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210132870"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert S. Rosenkranz","raw_affiliation_strings":["Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A","institution_ids":["https://openalex.org/I4210132870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010935727","display_name":"Robert Mermelstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132870","display_name":"Xerox (United States)","ror":"https://ror.org/03jwzwq24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210132870"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Mermelstein","raw_affiliation_strings":["Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for the Environmental Health Sciences and Department of Epidemiology/Community Health, School of Medicine, Case Western Reserve University, Cleveland OH 44106 U.S.A","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Joseph C. Wilson Center for Technology, Xerox Corporation, Rochester, NY 14644 U.S.A","institution_ids":["https://openalex.org/I4210132870"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":3.4289,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.92909013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"92","issue":"1-2","first_page":"29","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitrated-polycyclic-aromatic-hydrocarbons","display_name":"nitro-PAHs","score":0.9710000157356262},{"id":"https://openalex.org/keywords/chemical-activation","display_name":"chemical activation","score":0.7689999938011169},{"id":"https://openalex.org/keywords/nitroreductase","display_name":"nitroreductase","score":0.7400000095367432},{"id":"https://openalex.org/keywords/hydroxylamine","display_name":"hydroxylamine","score":0.6759999990463257},{"id":"https://openalex.org/keywords/zinc-dust","display_name":"zinc dust","score":0.6710000038146973},{"id":"https://openalex.org/keywords/salmonella-mutagenicity-assay","display_name":"Salmonella mutagenicity assay","score":0.875},{"id":"https://openalex.org/keywords/carcinogens","display_name":"carcinogens","score":0.765999972820282},{"id":"https://openalex.org/keywords/microsomal-preparation","display_name":"microsomal preparation","score":0.6129999756813049},{"id":"https://openalex.org/keywords/nitro-group-reduction","display_name":"nitro group reduction","score":0.6119999885559082}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8464382886886597},{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.7441211938858032},{"id":"https://openalex.org/C2780639532","wikidata":"https://www.wikidata.org/wiki/Q7041427","display_name":"Nitro","level":3,"score":0.6521243453025818},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.5969905853271484},{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.5674172639846802},{"id":"https://openalex.org/C2781326480","wikidata":"https://www.wikidata.org/wiki/Q7041501","display_name":"Nitroreductase","level":3,"score":0.5620891451835632},{"id":"https://openalex.org/C2776639595","wikidata":"https://www.wikidata.org/wiki/Q221696","display_name":"Mutagen","level":3,"score":0.5441885590553284},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.4972362816333771},{"id":"https://openalex.org/C87644729","wikidata":"https://www.wikidata.org/wiki/Q547502","display_name":"Microsome","level":3,"score":0.4700274169445038},{"id":"https://openalex.org/C2780554229","wikidata":"https://www.wikidata.org/wiki/Q422772","display_name":"Nitro compound","level":4,"score":0.4438525438308716},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.39350199699401855},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.31428849697113037},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08049234747886658},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002273","descriptor_name":"Carcinogens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002273","descriptor_name":"Carcinogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009152","descriptor_name":"Mutagenicity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009153","descriptor_name":"Mutagens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009281","descriptor_name":"Naphthalenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009600","descriptor_name":"Nitroquinolines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012486","descriptor_name":"Salmonella typhimurium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015032","descriptor_name":"Zinc","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0027-5107(82)90207-x","doi":"https://doi.org/10.1016/0027-5107(82)90207-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(82)90207-x","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research","raw_type":"journal-article"},{"id":"pmid:7045649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7045649","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W74781306","https://openalex.org/W125143731","https://openalex.org/W1538458616","https://openalex.org/W1963701151","https://openalex.org/W1967502884","https://openalex.org/W1968465080","https://openalex.org/W1970468813","https://openalex.org/W1971392827","https://openalex.org/W1973195696","https://openalex.org/W1977330475","https://openalex.org/W1996197564","https://openalex.org/W2008160834","https://openalex.org/W2013866353","https://openalex.org/W2028264365","https://openalex.org/W2031653666","https://openalex.org/W2046645062","https://openalex.org/W2055678782","https://openalex.org/W2057147465","https://openalex.org/W2067827253","https://openalex.org/W2110186864","https://openalex.org/W2164684230","https://openalex.org/W2336601286","https://openalex.org/W2887198846"],"related_works":["https://openalex.org/W2092706848","https://openalex.org/W2031653666","https://openalex.org/W32869502","https://openalex.org/W2365305965","https://openalex.org/W2982065662","https://openalex.org/W2008750729","https://openalex.org/W1547817405","https://openalex.org/W2057606673","https://openalex.org/W2290909658","https://openalex.org/W1997453512"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}