{"id":"https://openalex.org/W2020759797","doi":"https://doi.org/10.1258/0956462011923390","title":"Gynaecomastia in a male patient during stavudine and didanosine treatment for HIV infection","display_name":"Gynaecomastia in a male patient during stavudine and didanosine treatment for HIV infection","publication_year":2001,"publication_date":"2001-07-01","ids":{"openalex":"https://openalex.org/W2020759797","doi":"https://doi.org/10.1258/0956462011923390","mag":"2020759797","pmid":"https://pubmed.ncbi.nlm.nih.gov/11394987"},"language":"en","primary_location":{"id":"doi:10.1258/0956462011923390","doi":"https://doi.org/10.1258/0956462011923390","is_oa":false,"landing_page_url":"https://doi.org/10.1258/0956462011923390","pdf_url":null,"source":{"id":"https://openalex.org/S30045969","display_name":"International Journal of STD & AIDS","issn_l":"0956-4624","issn":["0956-4624","1758-1052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of STD & AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110124899","display_name":"Cristina Aquilina","orcid":"https://orcid.org/0009-0002-2759-3646","observed_orcids":["https://orcid.org/0009-0002-2759-3646"]},"institutions":[{"id":"https://openalex.org/I4210166011","display_name":"H\u00f4pital de La Grave","ror":"https://ror.org/05x8jna23","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210166011"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Aquilina","raw_affiliation_strings":["Service de Dermato-v\u00e9n\u00e9r\u00e9ologie, H\u00f4pital La Grave, Place Lange, 31052 Toulouse C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Dermato-v\u00e9n\u00e9r\u00e9ologie, H\u00f4pital La Grave, Place Lange, 31052 Toulouse C\u00e9dex, France","institution_ids":["https://openalex.org/I4210166011"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014402327","display_name":"Roland Viraben","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166011","display_name":"H\u00f4pital de La Grave","ror":"https://ror.org/05x8jna23","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210166011"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"R Viraben","raw_affiliation_strings":["Service de Dermato-v\u00e9n\u00e9r\u00e9ologie, H\u00f4pital La Grave, Place Lange, 31052 Toulouse C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Dermato-v\u00e9n\u00e9r\u00e9ologie, H\u00f4pital La Grave, Place Lange, 31052 Toulouse C\u00e9dex, France","institution_ids":["https://openalex.org/I4210166011"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210166011"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":1.2275,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.7863368,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"12","issue":"7","first_page":"481","last_page":"482"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13097","display_name":"Male Breast Health Studies","score":0.020500000566244125,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gynecomastia","display_name":"gynecomastia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.7590000033378601},{"id":"https://openalex.org/keywords/stavudine","display_name":"stavudine","score":0.9850000143051147},{"id":"https://openalex.org/keywords/didanosine","display_name":"didanosine","score":1.0},{"id":"https://openalex.org/keywords/lipodystrophy","display_name":"lipodystrophy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/nucleoside-reverse-transcriptase-inhibitors","display_name":"nucleoside reverse transcriptase inhibitors","score":0.8600000143051147},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.7129999995231628},{"id":"https://openalex.org/keywords/antiretroviral-therapy-adverse-effects","display_name":"antiretroviral therapy adverse effects","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C2777447569","wikidata":"https://www.wikidata.org/wiki/Q422606","display_name":"Didanosine","level":5,"score":0.9652882218360901},{"id":"https://openalex.org/C2779889181","wikidata":"https://www.wikidata.org/wiki/Q423984","display_name":"Stavudine","level":5,"score":0.9394086599349976},{"id":"https://openalex.org/C2780941825","wikidata":"https://www.wikidata.org/wiki/Q1538213","display_name":"Lipodystrophy","level":5,"score":0.8753512501716614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8487071990966797},{"id":"https://openalex.org/C2777333352","wikidata":"https://www.wikidata.org/wiki/Q2689559","display_name":"Nucleoside analogue","level":3,"score":0.5763340592384338},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5578271746635437},{"id":"https://openalex.org/C2779546735","wikidata":"https://www.wikidata.org/wiki/Q3500973","display_name":"Lipoatrophy","level":5,"score":0.546533465385437},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4121735990047455},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3432546854019165},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3413209021091461},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.33856451511383057},{"id":"https://openalex.org/C2776452011","wikidata":"https://www.wikidata.org/wiki/Q311463","display_name":"Sida","level":4,"score":0.27393555641174316},{"id":"https://openalex.org/C2780216070","wikidata":"https://www.wikidata.org/wiki/Q198504","display_name":"Zidovudine","level":4,"score":0.21395495533943176},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.20768749713897705},{"id":"https://openalex.org/C2776543447","wikidata":"https://www.wikidata.org/wiki/Q28734","display_name":"Nucleoside","level":2,"score":0.17859673500061035},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.15258175134658813},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09519118070602417},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0763491690158844}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006177","descriptor_name":"Gynecomastia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D006679","descriptor_name":"HIV Seropositivity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006679","descriptor_name":"HIV Seropositivity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008060","descriptor_name":"Lipodystrophy","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016049","descriptor_name":"Didanosine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D018119","descriptor_name":"Stavudine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1258/0956462011923390","doi":"https://doi.org/10.1258/0956462011923390","is_oa":false,"landing_page_url":"https://doi.org/10.1258/0956462011923390","pdf_url":null,"source":{"id":"https://openalex.org/S30045969","display_name":"International Journal of STD & AIDS","issn_l":"0956-4624","issn":["0956-4624","1758-1052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of STD & AIDS","raw_type":"journal-article"},{"id":"pmid:11394987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11394987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of STD & AIDS","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2166097830","https://openalex.org/W2291516629","https://openalex.org/W7209887417","https://openalex.org/W1991698436","https://openalex.org/W2441958976","https://openalex.org/W2313259694","https://openalex.org/W2053349328","https://openalex.org/W2012973635","https://openalex.org/W2028699638","https://openalex.org/W2782654988"],"abstract_inverted_index":{"We":[0,16],"report":[1],"a":[2,8,13],"case":[3],"of":[4,20,27],"gynaecomastia":[5],"developed":[6],"in":[7,24],"HIV-seropositive":[9],"man,":[10],"associated":[11],"with":[12],"severe":[14],"lipodystrophy.":[15],"hypothesize":[17],"the":[18,25,36],"responsibility":[19],"stavudine":[21],"and":[22],"didanosine":[23],"development":[26],"these":[28],"2":[29],"complications.":[30],"If":[31],"many":[32],"reports":[33],"suggest":[34],"that":[35],"protease":[37],"inhibitors":[38],"may":[39,46],"promote":[40],"gynaecomastia,":[41],"long-term":[42],"nucleoside":[43],"analogue":[44],"therapy":[45],"also":[47],"cause":[48],"this":[49],"side":[50],"effect.":[51]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}