{"id":"https://openalex.org/W2020683369","doi":"https://doi.org/10.1117/12.2006489","title":"Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin","display_name":"Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin","publication_year":2013,"publication_date":"2013-02-22","ids":{"openalex":"https://openalex.org/W2020683369","doi":"https://doi.org/10.1117/12.2006489","mag":"2020683369"},"language":"en","primary_location":{"id":"doi:10.1117/12.2006489","doi":"https://doi.org/10.1117/12.2006489","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2006489","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029980254","display_name":"Jamshid Sourati","orcid":"https://orcid.org/0000-0002-4893-2793","observed_orcids":["https://orcid.org/0000-0002-4893-2793"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jamshid Sourati","raw_affiliation_strings":["Northeastern Univ. (United States)","Northeastern University United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northeastern Univ. (United States)","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Northeastern University United States","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074048076","display_name":"K\u0131van\u00e7 K\u00f6se","orcid":"https://orcid.org/0000-0003-3185-2639","observed_orcids":["https://orcid.org/0000-0003-3185-2639"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kivanc Kose","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Ctr. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Ctr. (United States)","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011252033","display_name":"Milind M. Rajadhyaksha","orcid":"https://orcid.org/0000-0002-6323-4547","observed_orcids":["https://orcid.org/0000-0002-6323-4547"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Milind Rajadhyaksha","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Ctr. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Ctr. (United States)","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042038501","display_name":"Jennifer Dy","orcid":"https://orcid.org/0000-0002-8430-134X","observed_orcids":["https://orcid.org/0000-0002-8430-134X"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer G. Dy","raw_affiliation_strings":["Northeastern Univ. (United States)","Northeastern University United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northeastern Univ. (United States)","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Northeastern University United States","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083261801","display_name":"Deniz Erdogmus B","orcid":"https://orcid.org/0000-0002-1114-3539","observed_orcids":["https://orcid.org/0000-0002-1114-3539"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deniz Erdogmus","raw_affiliation_strings":["Northeastern Univ. (United States)","Northeastern University United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northeastern Univ. (United States)","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Northeastern University United States","institution_ids":["https://openalex.org/I12912129"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079980080","display_name":"Dana H. Brooks","orcid":"https://orcid.org/0000-0003-3231-6715","observed_orcids":["https://orcid.org/0000-0003-3231-6715"]},"institutions":[{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana H. Brooks","raw_affiliation_strings":["Northeastern Univ. (United States)","Northeastern University United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northeastern Univ. (United States)","institution_ids":["https://openalex.org/I12912129"]},{"raw_affiliation_string":"Northeastern University United States","institution_ids":["https://openalex.org/I12912129"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2857,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.90871795,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"8565","issue":null,"first_page":"856503","last_page":"856503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.4417000114917755,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.4417000114917755,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.3578999936580658,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.04899999871850014,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reflectance-confocal-microscopy","display_name":"reflectance confocal microscopy","score":0.8980000019073486},{"id":"https://openalex.org/keywords/dermal-epidermal-junction","display_name":"basement membrane zone","score":0.9100000262260437},{"id":"https://openalex.org/keywords/wrinkle-detection","display_name":"wrinkle detection","score":0.7210000157356262},{"id":"https://openalex.org/keywords/skin-imaging","display_name":"skin imaging","score":0.6499999761581421},{"id":"https://openalex.org/keywords/automated-image-analysis","display_name":"automated image analysis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/human-skin","display_name":"human skin","score":0.46399998664855957},{"id":"https://openalex.org/keywords/depth-information","display_name":"depth information","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C136009344","wikidata":"https://www.wikidata.org/wiki/Q336201","display_name":"Confocal","level":2,"score":0.7615024447441101},{"id":"https://openalex.org/C108597893","wikidata":"https://www.wikidata.org/wiki/Q663650","display_name":"Reflectivity","level":2,"score":0.6266051530838013},{"id":"https://openalex.org/C160697094","wikidata":"https://www.wikidata.org/wiki/Q1233197","display_name":"Oblique case","level":2,"score":0.5644733905792236},{"id":"https://openalex.org/C2779178360","wikidata":"https://www.wikidata.org/wiki/Q902045","display_name":"Confocal microscopy","level":2,"score":0.5543377995491028},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5071015357971191},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5018315315246582},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4256385862827301},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.38541465997695923},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.36960548162460327},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.36694347858428955},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.26666805148124695},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1394963562488556},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2006489","doi":"https://doi.org/10.1117/12.2006489","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2006489","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2128721420","https://openalex.org/W2764869177","https://openalex.org/W2121924261","https://openalex.org/W2085899139","https://openalex.org/W2655039468","https://openalex.org/W3016736514","https://openalex.org/W2952881476","https://openalex.org/W138561214","https://openalex.org/W6967081288","https://openalex.org/W3207950776"],"abstract_inverted_index":{"Reflectance":[0],"Confocal":[1],"Microscopic":[2],"(RCM)":[3],"imaging":[4],"of":[5,23,28,37,52,71],"obliquely-oriented":[6],"optical":[7],"sections,":[8],"rather":[9],"than":[10],"with":[11,47],"traditional":[12],"z-stacks,":[13,48],"shows":[14],"depth":[15],"information":[16,96],"that":[17,39],"more":[18],"closely":[19],"mimics":[20],"the":[21,35,53],"appearance":[22],"skin":[24],"in":[25,57,73,88],"orthogonal":[26],"sections":[27],"histology.":[29],"This":[30],"approach":[31],"may":[32],"considerably":[33],"reduce":[34],"amount":[36],"data":[38],"must":[40],"be":[41],"acquired":[42],"and":[43],"processed.":[44],"However,":[45],"as":[46],"purely":[49],"visual":[50],"detection":[51],"dermal-epidermal":[54],"junction":[55],"(DEJ)":[56],"oblique":[58,76],"images":[59],"remains":[60],"challenging.":[61],"Here,":[62],"we":[63,80],"have":[64],"extended":[65],"our":[66],"original":[67],"algorithm":[68,83],"for":[69,84,97],"localization":[70],"DEJ":[72,98],"z-stacks":[74],"to":[75,90],"images.":[77],"In":[78],"addition,":[79],"developed":[81],"an":[82],"detecting":[85],"wrinkles,":[86],"which":[87],"addition":[89],"its":[91],"intrinsic":[92],"merit,":[93],"gives":[94],"useful":[95],"detection.":[99]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}