{"id":"https://openalex.org/W2020663733","doi":"https://doi.org/10.1016/0042-6822(87)90008-0","title":"Persistent coinfection of T lymphocytes with HTLV-II and HIV and the role of syncytium formation in HIV-induced cytopathic effect","display_name":"Persistent coinfection of T lymphocytes with HTLV-II and HIV and the role of syncytium formation in HIV-induced cytopathic effect","publication_year":1987,"publication_date":"1987-10-01","ids":{"openalex":"https://openalex.org/W2020663733","doi":"https://doi.org/10.1016/0042-6822(87)90008-0","mag":"2020663733","pmid":"https://pubmed.ncbi.nlm.nih.gov/2821680"},"language":"en","primary_location":{"id":"doi:10.1016/0042-6822(87)90008-0","doi":"https://doi.org/10.1016/0042-6822(87)90008-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0042-6822(87)90008-0","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004036928","display_name":"David C. Montefiori","orcid":"https://orcid.org/0000-0003-0856-6319","observed_orcids":["https://orcid.org/0000-0003-0856-6319"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David C. Montefiori","raw_affiliation_strings":["Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232","Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085333102","display_name":"William Marvin Mitchell","orcid":"https://orcid.org/0000-0001-5024-9777","observed_orcids":["https://orcid.org/0000-0001-5024-9777"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William M. Mitchell","raw_affiliation_strings":["Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085333102"],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":{"value":3160,"currency":"USD","value_usd":3160},"apc_paid":null,"fwci":1.2153,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.79292929,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"160","issue":"2","first_page":"372","last_page":"378"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.023099999874830246,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/htlv-2","display_name":"HTLV-II","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hiv-coinfection","display_name":"HIV coinfection","score":0.8600000143051147},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.7369999885559082},{"id":"https://openalex.org/keywords/syncytium-formation","display_name":"syncytium formation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cytopathic-effect","display_name":"cytopathic effect","score":0.9750000238418579},{"id":"https://openalex.org/keywords/viral-interference","display_name":"viral interference","score":0.6510000228881836},{"id":"https://openalex.org/keywords/hiv-replication","display_name":"HIV replication","score":0.593999981880188},{"id":"https://openalex.org/keywords/reverse-transcriptase","display_name":"reverse transcriptase","score":0.6340000033378601},{"id":"https://openalex.org/keywords/htlv-iii","display_name":"HTLV-III","score":0.718999981880188},{"id":"https://openalex.org/keywords/lav","display_name":"LAV","score":0.9539999961853027}],"concepts":[{"id":"https://openalex.org/C40479148","wikidata":"https://www.wikidata.org/wiki/Q844460","display_name":"Syncytium","level":3,"score":0.9537900686264038},{"id":"https://openalex.org/C182615771","wikidata":"https://www.wikidata.org/wiki/Q1369386","display_name":"Lytic cycle","level":3,"score":0.8395140171051025},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8272081613540649},{"id":"https://openalex.org/C2777813720","wikidata":"https://www.wikidata.org/wiki/Q1243018","display_name":"Coinfection","level":3,"score":0.8016735315322876},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7584964632987976},{"id":"https://openalex.org/C2777890099","wikidata":"https://www.wikidata.org/wiki/Q7169345","display_name":"Permissiveness","level":4,"score":0.5654904246330261},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5538008213043213},{"id":"https://openalex.org/C156719811","wikidata":"https://www.wikidata.org/wiki/Q28774","display_name":"Reverse transcriptase","level":4,"score":0.5103976130485535},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.38186970353126526},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09538275003433228},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.0921487808227539},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06542736291885376}],"mesh":[{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002459","descriptor_name":"Cell Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003588","descriptor_name":"Cytopathogenic Effect, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D017977","descriptor_name":"Deltaretrovirus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0042-6822(87)90008-0","doi":"https://doi.org/10.1016/0042-6822(87)90008-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0042-6822(87)90008-0","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},{"id":"pmid:2821680","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2821680","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1501194130","https://openalex.org/W1517732553","https://openalex.org/W1538003463","https://openalex.org/W1968873679","https://openalex.org/W1971236744","https://openalex.org/W1971540091","https://openalex.org/W1972994253","https://openalex.org/W1977282539","https://openalex.org/W1979637191","https://openalex.org/W1981145710","https://openalex.org/W1981164507","https://openalex.org/W1985979064","https://openalex.org/W1991670386","https://openalex.org/W1996024432","https://openalex.org/W1997271169","https://openalex.org/W2007879674","https://openalex.org/W2008603298","https://openalex.org/W2013357966","https://openalex.org/W2015326137","https://openalex.org/W2016534065","https://openalex.org/W2021984449","https://openalex.org/W2022627708","https://openalex.org/W2030588812","https://openalex.org/W2035553258","https://openalex.org/W2042695720","https://openalex.org/W2046462022","https://openalex.org/W2053037116","https://openalex.org/W2056067293","https://openalex.org/W2059288217","https://openalex.org/W2059599036","https://openalex.org/W2060641378","https://openalex.org/W2063269692","https://openalex.org/W2079134008","https://openalex.org/W2079811310","https://openalex.org/W2086143621","https://openalex.org/W2086369756","https://openalex.org/W2091565871","https://openalex.org/W2094531254","https://openalex.org/W2113282092","https://openalex.org/W2114717159","https://openalex.org/W2138376996","https://openalex.org/W2150240929"],"related_works":["https://openalex.org/W1971236744","https://openalex.org/W2016029856","https://openalex.org/W4210897630","https://openalex.org/W2086369756","https://openalex.org/W2073360404","https://openalex.org/W2019890053","https://openalex.org/W2054057609","https://openalex.org/W2315052063","https://openalex.org/W4245720017","https://openalex.org/W2112511954"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}