{"id":"https://openalex.org/W2020647709","doi":"https://doi.org/10.1007/bf00314799","title":"Risk of acute upper gastrointestinal bleeding in patients with ulcerative disease and treatment with non-steroidal anti-inflammatory drugs (NSAIDs)","display_name":"Risk of acute upper gastrointestinal bleeding in patients with ulcerative disease and treatment with non-steroidal anti-inflammatory drugs (NSAIDs)","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W2020647709","doi":"https://doi.org/10.1007/bf00314799","mag":"2020647709","pmid":"https://pubmed.ncbi.nlm.nih.gov/2328744"},"language":"en","primary_location":{"id":"doi:10.1007/bf00314799","doi":"https://doi.org/10.1007/bf00314799","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00314799","pdf_url":null,"source":{"id":"https://openalex.org/S31780008","display_name":"European Journal of Clinical Pharmacology","issn_l":"0031-6970","issn":["0031-6970","1432-1041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006488107","display_name":"E Stodolnik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Stodolnik","raw_affiliation_strings":["Medical Division, Zieglerspital, Berne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Zieglerspital, Berne, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. Maurer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Maurer","raw_affiliation_strings":["Medical Division, Zieglerspital, Bern, Switzerland","Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Zieglerspital, Bern, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097007411","display_name":"R. Hoign\ufffd","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Hoign\ufffd","raw_affiliation_strings":["Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018080359","display_name":"T He\u00df","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Hess","raw_affiliation_strings":["Medical Division, Ana-Seiler-Haus, Berne, Switzerland","Medical Division, Berne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Ana-Seiler-Haus, Berne, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Medical Division, Berne, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077942379","display_name":"U. M\ufffdller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U. M\ufffdller","raw_affiliation_strings":["Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083393446","display_name":"F. Amonn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Amonn","raw_affiliation_strings":["Medical Division, Zieglerspital, Bern, Switzerland","Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Zieglerspital, Bern, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064704415","display_name":"Fred Halter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"F. Halter","raw_affiliation_strings":["Gastrointestinal Unit, Inselspital, Berne, Switzerland","Gastrointestinal Unit, Berne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastrointestinal Unit, Inselspital, Berne, Switzerland","institution_ids":["https://openalex.org/I2801112126"]},{"raw_affiliation_string":"Gastrointestinal Unit, Berne, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067269563","display_name":"Ruedi Maibach","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Maibach","raw_affiliation_strings":["Medical Division, Zieglerspital, Bern, Switzerland","Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Zieglerspital, Bern, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5097144830","display_name":"U. P. K\ufffdnzi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U. P. K\ufffdnzi","raw_affiliation_strings":["Medical Division, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Bern, Switzerland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":null,"fwci":4.9853,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.94400437,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"1","first_page":"31","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.1923000067472458,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.039900001138448715,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/upper-gastrointestinal-bleeding","display_name":"upper gastrointestinal bleeding","score":0.8399999737739563},{"id":"https://openalex.org/keywords/ulcerative-disease","display_name":"ulcerative disease","score":0.7580000162124634},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.9369999766349792},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9710000157356262},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.7620000243186951},{"id":"https://openalex.org/keywords/duodenal-ulcer","display_name":"duodenal ulcer","score":0.9950000047683716},{"id":"https://openalex.org/keywords/erosive-gastritis","display_name":"erosive gastritis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/drug-induced-hemorrhage","display_name":"drug-induced bleeding","score":0.5619999766349792},{"id":"https://openalex.org/keywords/relative-risk","display_name":"relative risk","score":0.6890000104904175},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.6200000047683716},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hospitalized-patients","display_name":"hospitalized patients","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.91350257396698},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7549686431884766},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.728060781955719},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.684359610080719},{"id":"https://openalex.org/C2776345487","wikidata":"https://www.wikidata.org/wiki/Q3144956","display_name":"Upper gastrointestinal bleeding","level":3,"score":0.5066881775856018},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.4935687780380249},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.4731912612915039},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.42981475591659546},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.3534286618232727},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.17948561906814575},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.09364238381385803}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004381","descriptor_name":"Duodenal Ulcer","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D004381","descriptor_name":"Duodenal Ulcer","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D004381","descriptor_name":"Duodenal Ulcer","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006471","descriptor_name":"Gastrointestinal Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010438","descriptor_name":"Peptic Ulcer Hemorrhage","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00314799","doi":"https://doi.org/10.1007/bf00314799","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00314799","pdf_url":null,"source":{"id":"https://openalex.org/S31780008","display_name":"European Journal of Clinical Pharmacology","issn_l":"0031-6970","issn":["0031-6970","1432-1041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Pharmacology","raw_type":"journal-article"},{"id":"pmid:2328744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2328744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1677175531","https://openalex.org/W1883361352","https://openalex.org/W1966155743","https://openalex.org/W1976754613","https://openalex.org/W1995294317","https://openalex.org/W1995678228","https://openalex.org/W2002217230","https://openalex.org/W2007260789","https://openalex.org/W2015088254","https://openalex.org/W2020730424","https://openalex.org/W2022399850","https://openalex.org/W2022787440","https://openalex.org/W2031775715","https://openalex.org/W2041638110","https://openalex.org/W2054303133","https://openalex.org/W2061477309","https://openalex.org/W2063560184","https://openalex.org/W2074800187","https://openalex.org/W2075074044","https://openalex.org/W2079669756","https://openalex.org/W2122159614","https://openalex.org/W2150290224","https://openalex.org/W2163226435","https://openalex.org/W2273444024","https://openalex.org/W2320705810","https://openalex.org/W2413028137","https://openalex.org/W2421786847","https://openalex.org/W2443444923","https://openalex.org/W2797407388","https://openalex.org/W4251121174","https://openalex.org/W4301914348"],"related_works":["https://openalex.org/W2055366026","https://openalex.org/W3032755085","https://openalex.org/W2434239367","https://openalex.org/W1992986411","https://openalex.org/W2417658996","https://openalex.org/W2358162704","https://openalex.org/W2359346264","https://openalex.org/W2382521503","https://openalex.org/W2158310507","https://openalex.org/W1966155743"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}