{"id":"https://openalex.org/W2020642879","doi":"https://doi.org/10.1159/000066265","title":"European Audit of Current Practice in Diagnosis and Treatment of Childhood Growth Hormone Deficiency","display_name":"European Audit of Current Practice in Diagnosis and Treatment of Childhood Growth Hormone Deficiency","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2020642879","doi":"https://doi.org/10.1159/000066265","mag":"2020642879","pmid":"https://pubmed.ncbi.nlm.nih.gov/12401943"},"language":"en","primary_location":{"id":"doi:10.1159/000066265","doi":"https://doi.org/10.1159/000066265","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000066265","pdf_url":null,"source":{"id":"https://openalex.org/S159506102","display_name":"Hormone Research in Paediatrics","issn_l":"1663-2818","issn":["1663-2818","1663-2826"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hormone Research in Paediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045917807","display_name":"Anders Juul","orcid":"https://orcid.org/0000-0002-0534-4350","observed_orcids":["https://orcid.org/0000-0002-0534-4350"]},"institutions":[{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Anders Juul","raw_affiliation_strings":["Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark. ajuul@dadlnet.dk","Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark. ajuul@dadlnet.dk","institution_ids":["https://openalex.org/I2802567020"]},{"raw_affiliation_string":"Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802567020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070978913","display_name":"Sergio Bernasconi","orcid":"https://orcid.org/0000-0002-1788-3052","observed_orcids":["https://orcid.org/0000-0002-1788-3052"]},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sergio Bernasconi","raw_affiliation_strings":["Department of Pediatrics, University of Modena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Modena, Italy","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032176497","display_name":"Peter Clayton","orcid":"https://orcid.org/0000-0003-1225-4537","observed_orcids":["https://orcid.org/0000-0003-1225-4537","https://orcid.org/0000-0001-7592-4302"]},"institutions":[{"id":"https://openalex.org/I4210160221","display_name":"Royal Manchester Children's Hospital","ror":"https://ror.org/052vjje65","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210092852","https://openalex.org/I4210160221"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter E. Clayton","raw_affiliation_strings":["Royal Manchester Children's Hospital, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Manchester Children's Hospital, Manchester, UK","institution_ids":["https://openalex.org/I4210160221"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044869014","display_name":"Wieland Kie\u00df","orcid":"https://orcid.org/0000-0003-4118-9455","observed_orcids":["https://orcid.org/0000-0003-4118-9455"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wieland Kiess","raw_affiliation_strings":["Department of Pediatrics, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Leipzig, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063242445","display_name":"Sabine DeMuinck-Keizer Schrama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142620","display_name":"Erasmus MC - Sophia Children\u2019s Hospital","ror":"https://ror.org/047afsm11","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686","https://openalex.org/I4210142620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Sabine DeMuinck-Keizer Schrama","raw_affiliation_strings":["Sophia Children's Hospital, Rotterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sophia Children's Hospital, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210142620"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2825,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.89255622,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"58","issue":"5","first_page":"233","last_page":"241"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/growth-hormone-deficiency","display_name":"growth hormone deficiency","score":0.9440000057220459},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.546999990940094},{"id":"https://openalex.org/keywords/growth-hormone-therapy","display_name":"growth hormone therapy","score":0.7710000276565552},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.8700000047683716},{"id":"https://openalex.org/keywords/cutoff-values","display_name":"cut-off values","score":0.8600000143051147},{"id":"https://openalex.org/keywords/dose-adjustment","display_name":"dose adjustment","score":0.628000020980835},{"id":"https://openalex.org/keywords/pediatric-endocrinologists","display_name":"pediatric endocrinologists","score":0.6679999828338623},{"id":"https://openalex.org/keywords/variation-in-clinical-practice","display_name":"clinical practice variation","score":0.7020000219345093},{"id":"https://openalex.org/keywords/european-society-for-paediatric-endocrinology","display_name":"European Society for Paediatric Endocrinology","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2779952775","wikidata":"https://www.wikidata.org/wiki/Q369262","display_name":"Growth hormone deficiency","level":4,"score":0.756889820098877},{"id":"https://openalex.org/C2778217198","wikidata":"https://www.wikidata.org/wiki/Q556977","display_name":"Cutoff","level":2,"score":0.6505570411682129},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6453648209571838},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.6223515272140503},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.5457077622413635},{"id":"https://openalex.org/C199521495","wikidata":"https://www.wikidata.org/wiki/Q181487","display_name":"Audit","level":2,"score":0.47470560669898987},{"id":"https://openalex.org/C89551170","wikidata":"https://www.wikidata.org/wiki/Q1777274","display_name":"Bone age","level":2,"score":0.47444355487823486},{"id":"https://openalex.org/C2780689927","wikidata":"https://www.wikidata.org/wiki/Q24766801","display_name":"Insulin-like growth factor","level":4,"score":0.4704163372516632},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.45636221766471863},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.4453262388706207},{"id":"https://openalex.org/C2779683239","wikidata":"https://www.wikidata.org/wiki/Q202849","display_name":"Turner syndrome","level":2,"score":0.42715728282928467},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42681148648262024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41478288173675537},{"id":"https://openalex.org/C2778135454","wikidata":"https://www.wikidata.org/wiki/Q5611754","display_name":"Growth hormone treatment","level":4,"score":0.411638081073761},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3998816907405853},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.3269602656364441},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.13058680295944214},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001827","descriptor_name":"Body Height","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001928","descriptor_name":"Brain Diseases, Metabolic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D001928","descriptor_name":"Brain Diseases, Metabolic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001928","descriptor_name":"Brain Diseases, Metabolic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006130","descriptor_name":"Growth Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006130","descriptor_name":"Growth Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006306","descriptor_name":"Health Surveys","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008485","descriptor_name":"Medical Audit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D011628","descriptor_name":"Puberty, Delayed","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011628","descriptor_name":"Puberty, Delayed","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017410","descriptor_name":"Practice Guidelines as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018972","descriptor_name":"Insulin-Like Growth Factor Binding Protein 3","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019382","descriptor_name":"Human Growth Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019382","descriptor_name":"Human Growth Hormone","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D019382","descriptor_name":"Human Growth Hormone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019963","descriptor_name":"Clinical Chemistry Tests","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D020249","descriptor_name":"Hormone Replacement Therapy","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1159/000066265","doi":"https://doi.org/10.1159/000066265","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000066265","pdf_url":null,"source":{"id":"https://openalex.org/S159506102","display_name":"Hormone Research in Paediatrics","issn_l":"1663-2818","issn":["1663-2818","1663-2826"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hormone Research in Paediatrics","raw_type":"journal-article"},{"id":"pmid:12401943","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12401943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hormone research","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire_cris_publications/5f15f073-de0b-4f9f-85eb-204bebf5b3a5","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/5f15f073-de0b-4f9f-85eb-204bebf5b3a5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Juul, A, Bernasconi, S, Clayton, PE, Kiess, W & Schrama, S 2002, 'European audit of current practice in diagnosis and treatment of childhood growth hormone deficiency', Hormone Research, vol. 58, pp. 233-241. https://doi.org/10.1159/000066265","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:pure.eur.nl:publications/5f15f073-de0b-4f9f-85eb-204bebf5b3a5","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/5f15f073-de0b-4f9f-85eb-204bebf5b3a5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hormone Research, 58, 233 - 241. Karger","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/c986f9d9-0a5a-4255-8e6c-355fe7aa10a8","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/c986f9d9-0a5a-4255-8e6c-355fe7aa10a8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Juul, A, Bernasconi, S, Clayton, P E, Kiess, W, DeMuinck-Keizer Schrama, S & Drugs and Therapeutics Committee of the European Society for Paediatric Endocrinology (ESPE) 2002, 'European audit of current practice in diagnosis and treatment of childhood growth hormone deficiency', Hormone Research, vol. 58, no. 5, pp. 233-41. https://doi.org/66265","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W43675721","https://openalex.org/W1970819518","https://openalex.org/W1981865861","https://openalex.org/W1983888476","https://openalex.org/W2020636054","https://openalex.org/W2029704846","https://openalex.org/W2033289116","https://openalex.org/W2039348599","https://openalex.org/W2039767017","https://openalex.org/W2095624101","https://openalex.org/W2117350664","https://openalex.org/W2123426154","https://openalex.org/W2606513528"],"related_works":["https://openalex.org/W2037885466","https://openalex.org/W2154684201","https://openalex.org/W2984675009","https://openalex.org/W2549184188","https://openalex.org/W2199183420","https://openalex.org/W89221723","https://openalex.org/W1964358004","https://openalex.org/W4254451072","https://openalex.org/W2102862738","https://openalex.org/W1994861144"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"present":[2,130],"survey":[3,131],"among":[4,164,363],"members":[5],"of":[6,16,23,32,41,61,78,92,97,112,121,155,195,213,235,240,293,356,360,369,387],"the":[7,30,33,44,59,62,68,79,109,119,129,159,174,181,193,214,238,294,336,341,353,390],"ESPE":[8],"on":[9,200,204,264],"current":[10,69,354],"practice":[11,70,355],"in":[12,29,71,88,108,278,283,325,352,389],"diagnosis":[13,38,120,357,384],"and":[14,27,39,67,144,186,224,267,304,327,358,372,382,385],"treatment":[15,40,241,359],"growth":[17,84,265],"hormone":[18],"(GH)":[19],"deficiency":[20],"(GHD)":[21],"is":[22,188,198],"great":[24],"clinical":[25],"relevance":[26],"importance":[28],"light":[31],"recently":[34],"published":[35],"guidelines":[36],"for":[37,134],"GHD":[42,122,362,388],"by":[43,152,248,290],"Growth":[45,63],"Hormone":[46,64],"Research":[47,65],"Society.":[48],"We":[49,74],"have":[50,348],"found":[51,75,349],"much":[52],"conformity":[53],"but":[54],"also":[55,158,309],"numerous":[56],"discrepancies":[57],"between":[58,184],"recommendations":[60],"Society":[66],"Europe.":[72],"RESULTS:":[73],"that":[76,192,333],"80%":[77],"pediatric":[80,365],"endocrinologists":[81],"included":[82],"insulin-like":[83],"factor":[85,154,183],"I":[86],"(IGF-I)":[87],"their":[89,168,229],"initial":[90,110],"evaluation":[91,111],"a":[93,113,153,320,380],"short":[94,114],"child":[95],"suspected":[96],"having":[98],"GHD,":[99],"whereas":[100,250],"only":[101,211,225],"22%":[102],"used":[103],"GH":[104,135,206,219,230,236,258,323,337,370],"provocative":[105,126,136],"testing":[106,137],"alone":[107],"child.":[115],"Sixty-eight":[116],"percent":[117,313],"confirmed":[118],"using":[123],"two":[124,140,149],"separate":[125],"tests.":[127],"In":[128,209,345],"cutoff":[132,162,196,373],"values":[133,163,197,374],"clustered":[138],"around":[139],"values;":[141],"10":[142],"ng/ml":[143],"20":[145],"mU/l.":[146],"Interestingly,":[147],"these":[148],"values,":[150],"differing":[151],"2,":[156],"were":[157,222,252],"most":[160],"prevalent":[161],"those":[165],"who":[166],"reported":[167,243,332],"assay":[169,207,220,231],"to":[170,245,255,300,328,340,378],"be":[171],"calibrated":[172],"against":[173],"WHO":[175],"International":[176],"Reference":[177],"Preparation":[178],"80/505":[179],"where":[180],"conversion":[182],"milligrams":[185],"milliunits":[187],"2.6.":[189],"This":[190],"suggests":[191],"selection":[194],"based":[199,263],"tradition":[201],"rather":[202],"than":[203],"specific":[205],"characteristics.":[208],"addition,":[210],"63%":[212],"respondents":[215],"actually":[216],"knew":[217,227],"what":[218],"they":[221,334],"using,":[223],"57%":[226],"how":[228],"was":[232,242,261,308],"calibrated.":[233],"Dosing":[234],"at":[237],"start":[239],"according":[244,254,299,339],"body":[246,256,301,305],"surface":[247,302],"39%,":[249],"59%":[251],"dosing":[253],"weight.":[257],"dose":[259,297,338],"adjustment":[260,298],"primarily":[262],"response":[266],"height":[268,279,284],"during":[269,322],"auxological":[270],"assessment":[271],"every":[272],"3-4":[273],"months":[274],"(height":[275],"velocity,":[276],"change":[277,282],"velocity":[280],"or":[281],"standard":[285],"deviation":[286],"scores)":[287],"as":[288],"indicated":[289],"almost":[291],"70%":[292],"respondents.":[295],"However,":[296],"(38%)":[303],"weight":[306],"(44%)":[307],"quite":[310],"common.":[311],"Sixty-five":[312],"measures":[314],"IGF-I":[315,342],"regularly":[316],"(at":[317],"least":[318],"once":[319],"year)":[321],"therapy":[324,386],"children,":[326],"our":[329],"surprise":[330],"17%":[331],"adjust":[335],"levels.":[343],"SUMMARY:":[344],"summary,":[346],"we":[347],"large":[350],"heterogeneity":[351],"childhood":[361],"European":[364],"endocrinologists.":[366],"Especially":[367],"standardizations":[368],"assays":[371],"are":[375],"urgently":[376],"required":[377],"ensure":[379],"uniform":[381],"correct":[383],"future.":[391]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}