{"id":"https://openalex.org/W2020587550","doi":"https://doi.org/10.1016/j.yjmcc.2005.08.005","title":"Spatiotemporal characteristics of SR Ca uptake and release in detubulated rat ventricular myocytes","display_name":"Spatiotemporal characteristics of SR Ca uptake and release in detubulated rat ventricular myocytes","publication_year":2005,"publication_date":"2005-09-30","ids":{"openalex":"https://openalex.org/W2020587550","doi":"https://doi.org/10.1016/j.yjmcc.2005.08.005","mag":"2020587550","pmid":"https://pubmed.ncbi.nlm.nih.gov/16198369"},"language":"en","primary_location":{"id":"doi:10.1016/j.yjmcc.2005.08.005","doi":"https://doi.org/10.1016/j.yjmcc.2005.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yjmcc.2005.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078489757","display_name":"Fabien Brette","orcid":"https://orcid.org/0000-0002-5406-4531","observed_orcids":["https://orcid.org/0000-0002-5406-4531"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F BRETTE","raw_affiliation_strings":["Department of Physiology, University of Bristol, Medical Sciences Building, Bristol BS8 1TD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Bristol, Medical Sciences Building, Bristol BS8 1TD, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048733831","display_name":"Sanda I. Despa","orcid":"https://orcid.org/0000-0002-2374-6177","observed_orcids":["https://orcid.org/0000-0002-2374-6177"]},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S DESPA","raw_affiliation_strings":["Department of Physiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA","institution_ids":["https://openalex.org/I1925986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020824899","display_name":"Donald M. Bers","orcid":"https://orcid.org/0000-0002-2237-9483","observed_orcids":["https://orcid.org/0000-0002-2237-9483"]},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D BERS","raw_affiliation_strings":["Department of Physiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA","institution_ids":["https://openalex.org/I1925986"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080513991","display_name":"Clive H. Orchard","orcid":"https://orcid.org/0000-0001-7714-5900","observed_orcids":["https://orcid.org/0000-0001-7714-5900"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"C ORCHARD","raw_affiliation_strings":["Department of Physiology, University of Bristol, Medical Sciences Building, Bristol BS8 1TD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Bristol, Medical Sciences Building, Bristol BS8 1TD, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5080513991"],"corresponding_institution_ids":["https://openalex.org/I36234482"],"apc_list":{"value":4120,"currency":"USD","value_usd":4120},"apc_paid":null,"fwci":1.9463,"has_fulltext":false,"cited_by_count":90,"citation_normalized_percentile":{"value":0.86940496,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"39","issue":"5","first_page":"804","last_page":"812"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sarcoplasmic-reticulum-calcium-uptake","display_name":"sarcoplasmic reticulum calcium uptake","score":0.9319999814033508},{"id":"https://openalex.org/keywords/calcium-release","display_name":"calcium release","score":0.5299999713897705},{"id":"https://openalex.org/keywords/t-tubules","display_name":"T-tubules","score":0.8659999966621399},{"id":"https://openalex.org/keywords/ventricular-myocytes","display_name":"ventricular myocytes","score":0.8659999966621399},{"id":"https://openalex.org/keywords/calcium-waves","display_name":"calcium waves","score":0.7929999828338623},{"id":"https://openalex.org/keywords/calcium-sparks","display_name":"calcium sparks","score":0.6050000190734863},{"id":"https://openalex.org/keywords/isoproterenol","display_name":"isoproterenol","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.5580000281333923},{"id":"https://openalex.org/keywords/calcium-overload","display_name":"calcium overload","score":0.5899999737739563}],"concepts":[{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.7715042233467102},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.6150045394897461},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.524089515209198},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5010724067687988},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.4344106912612915},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3708157539367676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2699527144432068},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.181257963180542},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08024084568023682},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07299578189849854},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D012519","descriptor_name":"Sarcoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.yjmcc.2005.08.005","doi":"https://doi.org/10.1016/j.yjmcc.2005.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yjmcc.2005.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},{"id":"pmid:16198369","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16198369","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular and cellular cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/55b775e6-ce12-4658-b90f-c6fe0937db05","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/55b775e6-ce12-4658-b90f-c6fe0937db05","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brette, F, Despa, S, Bers, D M & Orchard, C H 2005, 'Spatiotemporal characteristics of SR Ca2+ uptake and release in detubulated rat ventricular myocytes', Journal of molecular and cellular cardiology, vol. 39, no. 5, pp. 804-812. https://doi.org/10.1016/j.yjmcc.2005.08.005","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1216590070","display_name":"Ca and Na Transport in Heart Failure","funder_award_id":"R01HL064724","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G682699199","display_name":null,"funder_award_id":"HL30077","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337392","display_name":"Division of Electrical, Communications and Cyber Systems","ror":"https://ror.org/01krpsy48"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1492161308","https://openalex.org/W1856107376","https://openalex.org/W1857532475","https://openalex.org/W1988792839","https://openalex.org/W2003046582","https://openalex.org/W2006237744","https://openalex.org/W2014501709","https://openalex.org/W2022901757","https://openalex.org/W2041750868","https://openalex.org/W2042812063","https://openalex.org/W2058607911","https://openalex.org/W2062684112","https://openalex.org/W2088264606","https://openalex.org/W2093330924","https://openalex.org/W2096183879","https://openalex.org/W2102834464","https://openalex.org/W2104750607","https://openalex.org/W2118810404","https://openalex.org/W2120076709","https://openalex.org/W2121580874","https://openalex.org/W2122031584","https://openalex.org/W2125558148","https://openalex.org/W2125738242","https://openalex.org/W2131133264","https://openalex.org/W2134338008","https://openalex.org/W2140313980","https://openalex.org/W2140496691","https://openalex.org/W2145484503","https://openalex.org/W2148750197","https://openalex.org/W2151909975","https://openalex.org/W2155181139","https://openalex.org/W2170853736","https://openalex.org/W2172519975","https://openalex.org/W2334186356","https://openalex.org/W2977097895"],"related_works":["https://openalex.org/W2408076582","https://openalex.org/W2118151783","https://openalex.org/W2048961320","https://openalex.org/W4408246272","https://openalex.org/W1857532475","https://openalex.org/W2148750197","https://openalex.org/W2090598950","https://openalex.org/W2080485297","https://openalex.org/W2165424338","https://openalex.org/W2520364236"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}