{"id":"https://openalex.org/W2020204546","doi":"https://doi.org/10.1055/s-2001-15836","title":"Native kernspintomographische Darstellung des Morris-Hepatoms (MH-7777A) der Ratte","display_name":"Native kernspintomographische Darstellung des Morris-Hepatoms (MH-7777A) der Ratte","publication_year":2001,"publication_date":"2001-07-01","ids":{"openalex":"https://openalex.org/W2020204546","doi":"https://doi.org/10.1055/s-2001-15836","mag":"2020204546","pmid":"https://pubmed.ncbi.nlm.nih.gov/11512237"},"language":"de","primary_location":{"id":"doi:10.1055/s-2001-15836","doi":"https://doi.org/10.1055/s-2001-15836","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2001-15836","pdf_url":null,"source":{"id":"https://openalex.org/S4210212309","display_name":"R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren","issn_l":"1438-9010","issn":["1438-9010","1438-9029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058209824","display_name":"Gerrit Krupski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. Krupski","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Radiologie, Universit\u00e4tsklinikum Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Radiologie, Universit\u00e4tsklinikum Hamburg-Eppendorf","institution_ids":["https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008723150","display_name":"Detlev Ameis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Ameis","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Medizin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Medizin","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113532087","display_name":"Guellue Cataldegirmen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Cataldegirmen","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Chirurgie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Chirurgie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109095132","display_name":"Hermann Herbst","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Herbst","raw_affiliation_strings":["Institut f\u00fcr Pathologie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Pathologie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044469319","display_name":"Markus Henschel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. G. Henschel","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Radiologie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Radiologie","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"V. Nicolas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. Nicolas","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Radiologie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Radiologie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109804813","display_name":"Xavier Rogiers","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"X. Rogiers","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Medizin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Medizin","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087034511","display_name":"E. B\u00fccheler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. B\u00fccheler","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Radiologie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Radiologie","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2318,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.60445947,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"173","issue":"7","first_page":"639","last_page":"642"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.5351999998092651,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.5351999998092651,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.2257000058889389,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.10599999874830246,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/morris-hepatoma","display_name":"Morris hepatoma","score":0.9290000200271606},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.7710000276565552},{"id":"https://openalex.org/keywords/rat-tumor-model","display_name":"rat tumor model","score":0.675000011920929},{"id":"https://openalex.org/keywords/tumor-detection","display_name":"tumor detection","score":0.574999988079071},{"id":"https://openalex.org/keywords/fat-saturated-t2-weighted-imaging","display_name":"fat-saturated T2-weighted imaging","score":0.828000009059906},{"id":"https://openalex.org/keywords/cancer-detection-rate","display_name":"cancer detection rate","score":0.5410000085830688},{"id":"https://openalex.org/keywords/tumor-size-threshold","display_name":"tumor size threshold","score":0.4020000100135803},{"id":"https://openalex.org/keywords/buffalo-rats","display_name":"Buffalo rats","score":0.47699999809265137},{"id":"https://openalex.org/keywords/tumor-histology","display_name":"tumor histology","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5637013912200928},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5594978332519531},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.43798595666885376},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.43254998326301575},{"id":"https://openalex.org/C2780778865","wikidata":"https://www.wikidata.org/wiki/Q1130374","display_name":"Laparotomy","level":2,"score":0.4190838932991028},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4175495505332947},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.38952091336250305},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2687166929244995},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008114","descriptor_name":"Liver Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009368","descriptor_name":"Neoplasm Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011915","descriptor_name":"Rats, Inbred BUF","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-2001-15836","doi":"https://doi.org/10.1055/s-2001-15836","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2001-15836","pdf_url":null,"source":{"id":"https://openalex.org/S4210212309","display_name":"R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren","issn_l":"1438-9010","issn":["1438-9010","1438-9029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren","raw_type":"journal-article"},{"id":"pmid:11512237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11512237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1985879424","https://openalex.org/W2520684066","https://openalex.org/W2361891582","https://openalex.org/W2377477201","https://openalex.org/W3143097175","https://openalex.org/W2372414449","https://openalex.org/W2393806354","https://openalex.org/W905036036","https://openalex.org/W1999392197","https://openalex.org/W2059512204"],"abstract_inverted_index":{"Ziel:":[0],"Ziel":[1],"der":[2,24,85,98,119,151,154,163],"vorliegenden":[3],"Studie":[4],"war":[5,144],"es,":[6],"ein":[7,103,125],"Tumormodell":[8],"f\u00fcr":[9],"onkologische":[10],"Studien":[11],"mit":[12,105,127,162,184,201],"einem":[13],"differenzierten":[14],"und":[15,20,29,74,79],"implantierbaren":[16],"Lebertumor":[17],"zu":[18,26,195],"implementieren":[19],"die":[21,71,76,145,157,191],"Darstellbarkeit":[22],"in":[23,43,47,122,215,235,324,348,430],"MRT":[25,58,120,183],"\u00fcberpr\u00fcfen.":[27],"Material":[28,248],"Methoden:":[30],"Bei":[31,83,96],"20":[32,86,99,251,313],"m\u00e4nnlichen":[33],"Buffalo-Ratten":[34],"wurden":[35,70],"im":[36],"Rahmen":[37],"einer":[38,45,106,128,196],"Laparotomie":[39],"150":[40,260,405],"000":[41,261,406],"MH-7777A-Tumorzellen":[42],"Form":[44],"Suspension":[46],"den":[48],"rechten":[49],"Leberlappen":[50],"injiziert.":[51],"Nach":[52],"12":[53,267],"Tagen":[54],"erfolgte":[55],"eine":[56,172],"native":[57,182],"(T":[59],"1":[60,114,137,165,199,273,333,356,382,425],"w":[61,149,274,278,362,383],"SE,":[62,275],"T":[63,147,164,185,272,276,360,381,411],"2":[64,148,186,277,361,412],"TSE":[65,150,279,363],"fettsaturiert,":[66],"TIRM).":[67],"Im":[68],"Anschluss":[69],"Tiere":[72,87,100],"get\u00f6tet":[73],"seziert,":[75],"Tumoren":[77,193],"makro-":[78],"histopathologisch":[80],"untersucht.":[81],"Ergebnisse:":[82],"5":[84,139,310,358],"konnte":[88,121],"kein":[89],"Tumor":[90,126],"makroskopisch":[91],"oder":[92],"histologisch":[93],"nachgewiesen":[94,141],"werden.":[95,142],"15":[97,325,342],"fand":[101],"sich":[102],"Hepatom":[104],"mittleren":[107,129],"Gr\u00f6\u00dfe":[108,130,197],"von":[109,131,174,198,204],"3,1":[110],"mm":[111,133,200,329,352,426],"(\u00b1":[112,134,330,353],"1,7,":[113],"-":[115,138,334,357],"7":[116,335],"mm).":[117,336,359],"In":[118,309],"14":[123,339],"F\u00e4llen":[124],"2,7":[132],"1,5":[135],"mm;":[136,332,355],"mm)":[140],"Dabei":[143],"fettsaturierte":[146],"TIRM":[152],"bei":[153,177],"Tumordetektion":[155],"\u00fcberlegen,":[156],"beste":[158],"anatomische":[159],"Darstellung":[160],"gelang":[161],"-gewichteten":[166],"Sequenz.":[167],"Schlussfolgerungen:":[168],"Das":[169],"MH-7777A-Tumormodell":[170],"zeigt":[171],"Tumorangehrate":[173],"75":[175,395],"%":[176,206,396,432],"geringer":[178],"injizierter":[179],"Tumorzellzahl.":[180],"Die":[181],"-gewichteten,":[187],"fettsaturierten":[188],"Sequenzen":[189],"kann":[190],"implantierten":[192],"bis":[194],"hoher":[202],"Treffsicherheit":[203],"93":[205,431],"nachweisen.":[207],"Native":[208],"magnetic":[209],"resonance":[210],"imaging":[211,241],"of":[212,219,242,259,287,312,321,341,394,404,420,424,433],"morris":[213],"hepatoma":[214,234],"the":[216,220,236,243,322,371,374,399,434],"rat.":[217],"Goal":[218],"study":[221],"presented":[222],"was":[223,270,317,327,350,364,378],"to":[224,239],"establish":[225],"an":[226],"oncological":[227],"animal":[228],"model":[229,389],"for":[230,282,366],"implantable":[231],"and":[232,238,249,285,296,298],"differentiated":[233],"rat":[237],"evaluate":[240],"tumor":[244,256,283,316,367,388,401],"induced":[245],"using":[246,410],"MRI.":[247,307],"Methods:":[250],"male":[252],"buffalo":[253],"rats":[254,293],"underwent":[255],"cell":[257,402],"implantation":[258],"MH7777-A":[262,387],"cells":[263],"via":[264],"laparotomy.":[265],"After":[266],"days":[268],"MRI":[269,338,349,409],"performed":[271],"fs,":[280],"TIRM)":[281],"detection":[284,368,419],"measurement":[286],"size.":[288],"Immediately":[289],"there":[290],"after":[291],"all":[292],"were":[294,304,344],"killed":[295],"macroscopic":[297],"histological":[299],"examination":[300],"performed.":[301],"Pathological":[302],"findings":[303],"correlated":[305],"with":[306,370,391,398,415,422],"Results:":[308],"out":[311,340],"animals":[314,326],"no":[315],"found.":[318],"Mean":[319,346],"size":[320],"hepatomas":[323],"3.1":[328],"1.7":[331],"On":[337],"tumors":[343,421],"detectable.":[345],"diameter":[347],"2.7":[351],"1.5":[354],"superior":[365],"compared":[369],"TIRM,":[372],"while":[373],"best":[375],"anatomic":[376],"depiction":[377],"offered":[379],"by":[380],"SE.":[384],"Conclusions:":[385],"The":[386],"presents":[390],"a":[392,418],"rate":[393],"even":[397],"small":[400],"amount":[403],"cells.":[407],"With":[408],"weighted":[413],"sequences":[414],"fat":[416],"saturation":[417],"diameters":[423],"is":[427],"reliably":[428],"possible":[429],"cases.":[435]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}