{"id":"https://openalex.org/W2020150177","doi":"https://doi.org/10.1507/endocrj1954.26.239","title":"Effects of vasopressin and cyclic AMP on water transport at arachnoid villi of cats.","display_name":"Effects of vasopressin and cyclic AMP on water transport at arachnoid villi of cats.","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W2020150177","doi":"https://doi.org/10.1507/endocrj1954.26.239","mag":"2020150177","pmid":"https://pubmed.ncbi.nlm.nih.gov/225164"},"language":"en","primary_location":{"id":"doi:10.1507/endocrj1954.26.239","doi":"https://doi.org/10.1507/endocrj1954.26.239","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj1954.26.239","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj1954/26/2/26_2_239/_pdf","source":{"id":"https://openalex.org/S2755219162","display_name":"Endocrinologia Japonica","issn_l":"0013-7219","issn":["0013-7219","2185-6370"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinologia Japonica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/endocrj1954/26/2/26_2_239/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073122606","display_name":"Tadashi Noto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TADASHI NOTO","raw_affiliation_strings":["Department of Neuropharmacology and Neurochemistry, Institute of Higher Nervous Activity, Osaka University Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropharmacology and Neurochemistry, Institute of Higher Nervous Activity, Osaka University Medical School","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026281327","display_name":"Teruo Nakajima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TERUO NAKAJIMA","raw_affiliation_strings":["Department of Neuropharmacology and Neurochemistry, Institute of Higher Nervous Activity, Osaka University Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropharmacology and Neurochemistry, Institute of Higher Nervous Activity, Osaka University Medical School","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110208122","display_name":"Yoshiaki Saji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44892455","display_name":"Takeda (Japan)","ror":"https://ror.org/04hjbmv12","country_code":"JP","type":"company","lineage":["https://openalex.org/I44892455"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YOSHIAKI SAJI","raw_affiliation_strings":["Medicinal Research Laboratory, Takeda Chemical Industry, Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratory, Takeda Chemical Industry, Ltd","institution_ids":["https://openalex.org/I44892455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113769656","display_name":"Yuji Nagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44892455","display_name":"Takeda (Japan)","ror":"https://ror.org/04hjbmv12","country_code":"JP","type":"company","lineage":["https://openalex.org/I44892455"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YUJI NAGAWA","raw_affiliation_strings":["Medicinal Research Laboratory, Takeda Chemical Industry, Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratory, Takeda Chemical Industry, Ltd","institution_ids":["https://openalex.org/I44892455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6188,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.81571714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"2","first_page":"239","last_page":"244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.8324999809265137,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.8324999809265137,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.10260000079870224,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":0.030899999663233757,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":1.0},{"id":"https://openalex.org/keywords/camp","display_name":"cyclic AMP","score":0.9980000257492065},{"id":"https://openalex.org/keywords/arachnoid-villi","display_name":"arachnoid villi","score":0.9010000228881836},{"id":"https://openalex.org/keywords/water-transport","display_name":"water transport","score":0.8820000290870667},{"id":"https://openalex.org/keywords/superior-sagittal-sinus","display_name":"superior sagittal sinus","score":0.9779999852180481},{"id":"https://openalex.org/keywords/meninges","display_name":"meninges","score":0.8090000152587891},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.9509999752044678},{"id":"https://openalex.org/keywords/intracranial-pressure-regulation","display_name":"intracranial pressure regulation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/cats","display_name":"cats","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.9405173063278198},{"id":"https://openalex.org/C2776620988","wikidata":"https://www.wikidata.org/wiki/Q4115976","display_name":"Superior sagittal sinus","level":3,"score":0.7760705947875977},{"id":"https://openalex.org/C2776403516","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Meninges","level":2,"score":0.6751566529273987},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.6030847430229187},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.471157431602478},{"id":"https://openalex.org/C2779904517","wikidata":"https://www.wikidata.org/wiki/Q5008900","display_name":"CATS","level":2,"score":0.45817941427230835},{"id":"https://openalex.org/C2778815084","wikidata":"https://www.wikidata.org/wiki/Q79803","display_name":"Guinea pig","level":2,"score":0.4504469633102417},{"id":"https://openalex.org/C2992163139","wikidata":"https://www.wikidata.org/wiki/Q155930","display_name":"Water transport","level":3,"score":0.44799157977104187},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4173554480075836},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3670356273651123},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3352639079093933},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.312791109085083},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26852649450302124},{"id":"https://openalex.org/C2988574769","wikidata":"https://www.wikidata.org/wiki/Q2259545","display_name":"Water flow","level":2,"score":0.18291205167770386},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.08285269141197205},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.07506212592124939},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.0},{"id":"https://openalex.org/C159390177","wikidata":"https://www.wikidata.org/wiki/Q9161265","display_name":"Soil science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001099","descriptor_name":"Arachnoid","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001099","descriptor_name":"Arachnoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004388","descriptor_name":"Dura Mater","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004388","descriptor_name":"Dura Mater","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014667","descriptor_name":"Vasopressins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1507/endocrj1954.26.239","doi":"https://doi.org/10.1507/endocrj1954.26.239","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj1954.26.239","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj1954/26/2/26_2_239/_pdf","source":{"id":"https://openalex.org/S2755219162","display_name":"Endocrinologia Japonica","issn_l":"0013-7219","issn":["0013-7219","2185-6370"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinologia Japonica","raw_type":"journal-article"},{"id":"pmid:225164","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/225164","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinologia japonica","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1507/endocrj1954.26.239","doi":"https://doi.org/10.1507/endocrj1954.26.239","is_oa":true,"landing_page_url":"https://doi.org/10.1507/endocrj1954.26.239","pdf_url":"https://www.jstage.jst.go.jp/article/endocrj1954/26/2/26_2_239/_pdf","source":{"id":"https://openalex.org/S2755219162","display_name":"Endocrinologia Japonica","issn_l":"0013-7219","issn":["0013-7219","2185-6370"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313267","host_organization_name":"Japan Endocrine Society","host_organization_lineage":["https://openalex.org/P4310313267"],"host_organization_lineage_names":["Japan Endocrine Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinologia Japonica","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2020150177.pdf","grobid_xml":"https://content.openalex.org/works/W2020150177.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1970305526","https://openalex.org/W42913028","https://openalex.org/W2067310997","https://openalex.org/W2074936851","https://openalex.org/W42552264","https://openalex.org/W2032835850","https://openalex.org/W2018254178","https://openalex.org/W2059861640","https://openalex.org/W2059183201","https://openalex.org/W2429463212"],"abstract_inverted_index":{"The":[0,27,51],"effects":[1],"of":[2,25,34,41,63,122,131,137,151,161],"vasopressin":[3,138,152],"and":[4,69,99],"cyclic":[5,123,143],"AMP":[6,105,124],"on":[7],"water":[8,81,97],"transport":[9,74,98],"at":[10,38],"arachnoid":[11,70],"villi":[12],"into":[13],"the":[14,21,30,39,42,57,60,64,79,84,96,115,135,159],"superior":[15,31],"sagittal":[16,32],"sinus":[17,33,65],"were":[18,53],"examined":[19],"using":[20],"isolated":[22],"meninges":[23,28],"preparations":[24],"cats.":[26],"preparation,":[29],"which":[35],"was":[36,45,66,75,102,111,156],"opened":[37,61],"midline":[40],"outer":[43],"surface,":[44],"held":[46],"between":[47],"two":[48],"polyethylene":[49],"tubes.":[50],"tubes":[52],"fixed":[54],"vertically":[55],"in":[56,127,153],"way":[58],"that":[59,130,134],"surface":[62,71],"directed":[67],"downward":[68],"upward.":[72],"Water":[73],"determined":[76],"by":[77],"measuring":[78],"tritiated":[80],"dripping":[82],"through":[83,142],"membrane":[85],"preparation.":[86],"Vasopressin":[87],"from":[88,106],"less":[89],"than":[90],"50":[91],"to":[92,108,113],"500":[93],"muU/ml":[94],"accelerated":[95],"this":[100],"effect":[101,117,121,136],"dose-dependent.":[103],"Cyclic":[104],"0.5":[107],"10":[109],"mM":[110],"proved":[112],"manifest":[114],"same":[116],"as":[118],"vasopressin.":[119],"This":[120],"appeared":[125],"rapidly":[126],"comparison":[128],"with":[129],"vasopressin,":[132],"suggesting":[133],"may":[139],"be":[140],"manifested":[141],"AMP.":[144],"From":[145],"these":[146],"findings":[147],"a":[148],"physiological":[149],"role":[150],"cerebrospinal":[154],"fluid":[155],"discussed":[157],"regarding":[158],"regulation":[160],"intracranial":[162],"pressure.":[163]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}