{"id":"https://openalex.org/W2020036447","doi":"https://doi.org/10.1200/jco.2012.43.0256","title":"Reply to M.C. Chamberlain et al","display_name":"Reply to M.C. Chamberlain et al","publication_year":2012,"publication_date":"2012-05-30","ids":{"openalex":"https://openalex.org/W2020036447","doi":"https://doi.org/10.1200/jco.2012.43.0256","mag":"2020036447"},"language":"fr","primary_location":{"id":"doi:10.1200/jco.2012.43.0256","doi":"https://doi.org/10.1200/jco.2012.43.0256","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2012.43.0256","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2012.43.0256?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"letter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2012.43.0256?role=tab","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044135383","display_name":"Paul W. Sperduto","orcid":"https://orcid.org/0000-0002-4628-7161","observed_orcids":["https://orcid.org/0000-0002-4628-7161"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul W. Sperduto","raw_affiliation_strings":["University of Minnesota; Minneapolis Radiation Oncology, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota; Minneapolis Radiation Oncology, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029973407","display_name":"Norbert Kased","orcid":"https://orcid.org/0009-0006-2903-2788","observed_orcids":["https://orcid.org/0009-0006-2903-2788"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norbert Kased","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029517342","display_name":"David Roberge","orcid":"https://orcid.org/0000-0001-8747-648X","observed_orcids":["https://orcid.org/0000-0001-8747-648X"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"David Roberge","raw_affiliation_strings":["McGill University Health Center, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McGill University Health Center, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068443720","display_name":"Zhiyuan Xu","orcid":"https://orcid.org/0000-0002-7257-6856","observed_orcids":["https://orcid.org/0000-0002-7257-6856"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhiyuan Xu","raw_affiliation_strings":["Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082698708","display_name":"Ryan Shanley","orcid":"https://orcid.org/0000-0003-2398-5466","observed_orcids":["https://orcid.org/0000-0003-2398-5466"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryan Shanley","raw_affiliation_strings":["University of Minnesota, Masonic Cancer Center, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota, Masonic Cancer Center, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008133433","display_name":"Xianghua Luo","orcid":"https://orcid.org/0000-0001-7501-6582","observed_orcids":["https://orcid.org/0000-0001-7501-6582"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xianghua Luo","raw_affiliation_strings":["University of Minnesota, Masonic Cancer Center; University of Minnesota, School of Public Health, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota, Masonic Cancer Center; University of Minnesota, School of Public Health, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039465135","display_name":"Penny K. Sneed","orcid":"https://orcid.org/0000-0003-0487-4250","observed_orcids":["https://orcid.org/0000-0003-0487-4250"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Penny K. Sneed","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058440874","display_name":"Samuel T. Chao","orcid":"https://orcid.org/0000-0002-1087-2764","observed_orcids":["https://orcid.org/0000-0002-1087-2764"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel T. Chao","raw_affiliation_strings":["Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022741317","display_name":"Robert John Weil","orcid":"https://orcid.org/0000-0001-5674-4373","observed_orcids":["https://orcid.org/0000-0001-5674-4373"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J. Weil","raw_affiliation_strings":["Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087295298","display_name":"John H. Suh","orcid":"https://orcid.org/0000-0001-9523-2637","observed_orcids":["https://orcid.org/0000-0001-9523-2637"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Suh","raw_affiliation_strings":["Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035702352","display_name":"Amit K. Bhatt","orcid":"https://orcid.org/0009-0002-5590-8705","observed_orcids":["https://orcid.org/0009-0002-5590-8705"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit Bhatt","raw_affiliation_strings":["University of Wisconsin, Madison, WI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Wisconsin, Madison, WI","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110838455","display_name":"Ashley Wayne Jensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley W. Jensen","raw_affiliation_strings":["Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067520533","display_name":"Paul D. Brown","orcid":"https://orcid.org/0000-0003-0022-4533","observed_orcids":["https://orcid.org/0000-0003-0022-4533"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul D. Brown","raw_affiliation_strings":["Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045425111","display_name":"Helen Alice Shih","orcid":"https://orcid.org/0000-0003-1550-9726","observed_orcids":["https://orcid.org/0000-0003-1550-9726"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen A. Shih","raw_affiliation_strings":["Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090095693","display_name":"John P. Kirkpatrick","orcid":"https://orcid.org/0000-0002-4019-0350","observed_orcids":["https://orcid.org/0000-0002-4019-0350"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Kirkpatrick","raw_affiliation_strings":["Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109156278","display_name":"Laurie E. Gaspar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie E. Gaspar","raw_affiliation_strings":["University of Colorado School of Medicine, Aurora, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado School of Medicine, Aurora, CO","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091161682","display_name":"John B. Fiveash","orcid":"https://orcid.org/0000-0002-1129-2884","observed_orcids":["https://orcid.org/0000-0002-1129-2884"]},"institutions":[{"id":"https://openalex.org/I17301866","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67","country_code":"US","type":"education","lineage":["https://openalex.org/I17301866"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John B. Fiveash","raw_affiliation_strings":["University of Alabama Medical Center at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Alabama Medical Center at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I17301866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058373918","display_name":"Veronica Chiang","orcid":"https://orcid.org/0000-0003-1882-3876","observed_orcids":["https://orcid.org/0000-0003-1882-3876"]},"institutions":[{"id":"https://openalex.org/I2802730090","display_name":"Yale Cancer Center","ror":"https://ror.org/03j7sze86","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802730090","https://openalex.org/I4210117499","https://openalex.org/I4210165192"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Veronica Chiang","raw_affiliation_strings":["Yale University School of Medicine; Yale Cancer Center, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale University School of Medicine; Yale Cancer Center, New Haven, CT","institution_ids":["https://openalex.org/I2802730090","https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046534928","display_name":"Jonathan P.S. Knisely","orcid":"https://orcid.org/0000-0001-5975-8199","observed_orcids":["https://orcid.org/0000-0001-5975-8199"]},"institutions":[{"id":"https://openalex.org/I1302444339","display_name":"Northwell Health","ror":"https://ror.org/02bxt4m23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339"]},{"id":"https://openalex.org/I139290212","display_name":"Hofstra University","ror":"https://ror.org/03pm18j10","country_code":"US","type":"education","lineage":["https://openalex.org/I139290212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan P.S. Knisely","raw_affiliation_strings":["Hofstra University School of Medicine; North Shore\u2013Long Island Jewish Health System, Manhasset, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hofstra University School of Medicine; North Shore\u2013Long Island Jewish Health System, Manhasset, NY","institution_ids":["https://openalex.org/I1302444339","https://openalex.org/I139290212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003450382","display_name":"Christina Maria Sperduto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina Maria Sperduto","raw_affiliation_strings":["Dartmouth College, Hanover, NH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dartmouth College, Hanover, NH","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022319770","display_name":"NU Lin","orcid":"https://orcid.org/0000-0003-2263-5413","observed_orcids":["https://orcid.org/0000-0003-2263-5413"]},"institutions":[{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Lin","raw_affiliation_strings":["Dana-Farber Cancer Institute, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute, Boston, MA","institution_ids":["https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038585908","display_name":"Minesh P. Mehta","orcid":"https://orcid.org/0000-0002-4812-5713","observed_orcids":["https://orcid.org/0000-0002-4812-5713"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Minesh Mehta","raw_affiliation_strings":["Northwestern University, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northwestern University, Chicago, IL","institution_ids":["https://openalex.org/I111979921"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":21,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"26","first_page":"3316","last_page":"3317"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-metastases","display_name":"brain metastases","score":0.9869999885559082},{"id":"https://openalex.org/keywords/survival-estimation","display_name":"survival estimation","score":0.6230000257492065},{"id":"https://openalex.org/keywords/prognostic-stratification","display_name":"prognostic stratification","score":0.5789999961853027},{"id":"https://openalex.org/keywords/recursive-partitioning","display_name":"recursive partitioning","score":0.7559999823570251},{"id":"https://openalex.org/keywords/selection-bias","display_name":"selection bias","score":0.6150000095367432},{"id":"https://openalex.org/keywords/treatment-stratification","display_name":"treatment stratification","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8190086483955383}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2012.43.0256","doi":"https://doi.org/10.1200/jco.2012.43.0256","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2012.43.0256","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2012.43.0256?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1200/jco.2012.43.0256","doi":"https://doi.org/10.1200/jco.2012.43.0256","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2012.43.0256","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2012.43.0256?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2020036447.pdf","grobid_xml":"https://content.openalex.org/works/W2020036447.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W1974820090","https://openalex.org/W1975088650","https://openalex.org/W2038247960","https://openalex.org/W2060588419","https://openalex.org/W2123101598","https://openalex.org/W2158789700"],"related_works":["https://openalex.org/W4385623335","https://openalex.org/W2031597576","https://openalex.org/W2960906402","https://openalex.org/W1964395275","https://openalex.org/W1974820090","https://openalex.org/W3086164260","https://openalex.org/W2029860155","https://openalex.org/W1642085743","https://openalex.org/W2116590457","https://openalex.org/W4400017224"],"abstract_inverted_index":{"An":[0],"Accurate":[1],"and":[2,39,70,81,120,209,229,236,279,313,356],"Facile":[3],"Diagnosis-Specific":[4,260],"Tool":[5],"to":[6,75,180,248,290],"Estimate":[7],"Survival":[8],"for":[9,134,154,296,344],"Patients":[10],"With":[11],"Brain":[12],"Metastases.\"":[13],"2We":[14],"not":[15,122,217,305],"only":[16],"largely":[17],"agree":[18,203,320],"with":[19,117,136,178,204,239,274,288],"their":[20],"comments":[21],"but":[22,303],"have":[23,174],"included":[24],"them":[25],"in":[26,32,90,99,111,333,348],"the":[27,41,51,86,105,140,146,162,166,184,194,205,259,267,275,291,322,328],"article.As":[28],"we":[29,152,319],"explicitly":[30],"stated":[31],"our":[33,35,94,100],"article,":[34],"analysis":[36,150,195],"was":[37,56,72,157,196],"retrospective":[38,46,214,283],"has":[40,341],"inherent":[42],"weaknesses":[43],"of":[44,93,132,182,233,277,294,346],"any":[45],"study.We":[47],"remind":[48],"readers":[49],"that":[50,85,151,172,212,234,242,282,321],"Graded":[52,261],"Prospective":[53],"Assessment":[54,263],"(GPA)":[55],"originally":[57],"designed":[58],"from":[59,62],"prospective":[60,220,334],"data":[61,109,129,284],"four":[63],"Radiation":[64],"Therapy":[65],"Oncology":[66],"Group":[67],"(RTOG)":[68],"trials,":[69],"then":[71],"later":[73],"refined":[74],"be":[76,123,192,331],"diagnosis":[77],"specific.":[78],"[3]4][5]":[79],"Chamberlain":[80,208,278],"Silbergeld":[82,210,280],"1":[83,211,281],"suggest":[84],"survival":[87,106],"by":[88,107,159,207,258],"treatment":[89,108,163,293,317],"Table":[91,112,155],"2":[92,113,156],"article":[95],"is":[96,114,186,244,324,337],"problematic.Point":[97],"three":[98],"discussion":[101],"section":[102],"states:":[103],"\"Indeed,":[104],"shown":[110],"certainly":[115,304],"fraught":[116],"selection":[118],"bias":[119],"should":[121,330],"blindly":[124],"applied":[125],"or":[126],"expected.Nonetheless,":[127],"these":[128],"reflect":[130],"patterns":[131],"care":[133],"patients":[135],"brain":[137],"metastases":[138],"over":[139,327],"last":[141],"quarter":[142],"century.\"":[143],"2(p424)":[144],"Furthermore,":[145],"multivariate":[147],"Cox":[148],"regression":[149],"performed":[153],"stratified":[158,257],"institution;":[160],"hence,":[161],"differences":[164,168],"reflected":[165],"average":[167],"across":[169],"11":[170],"institutions":[171],"may":[173],"different":[175],"institutional":[176],"policies":[177],"respect":[179,289],"modality":[181],"therapy.Therefore,":[183],"result":[185],"more":[187],"generalizable":[188],"than":[189,266],"it":[190],"would":[191,271],"if":[193,255],"based":[197],"on":[198],"just":[199],"one":[200],"institution.We":[201],"also":[202],"comment":[206],"a":[213,219,310],"study":[215,235,243],"does":[216],"supplant":[218],"study,":[221],"specifically":[222],"RTOG":[223,352],"9508.":[224],"6":[225],"We":[226],"(P.W.S.,":[227],"L.E.G.,":[228],"M.P.M.)":[230],"are":[231,237,315],"authors":[232],"familiar":[238],"its":[240,251],"findings.Furthermore,":[241],"currently":[245],"undergoing":[246],"reanalysis":[247],"evaluate":[249],"whether":[250],"conclusions":[252],"might":[253],"vary":[254],"post":[256],"Prognostic":[262],"(DS-GPA)":[264],"rather":[265],"Recursive":[268],"Partitioning":[269],"Analysis.We":[270],"disagree,":[272],"however,":[273],"contention":[276],"provide":[285],"\"little":[286],"guidance":[287],"best":[292],"BM":[295],"specific":[297],"clinical":[298,307,353],"scenarios.\"The":[299],"DS-GPA":[300,323,340],"can":[301],"aid,":[302],"replace,":[306],"judgment":[308],"when":[309],"clinician,":[311],"patient,":[312],"family":[314],"making":[316],"choices.Finally,":[318],"an":[325],"improvement":[326],"RTOGRecursivePartitioningAnalysisclassificationandthattheDS-GPA":[329],"validated":[332],"trials.That":[335],"validation":[336],"already":[338],"underway.The":[339],"been":[342],"adopted":[343],"purposes":[345],"stratification":[347],"two":[349],"prospective,":[350],"randomized,":[351],"trials":[354],"(1118":[355],"1119).":[357]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}