{"id":"https://openalex.org/W2020006363","doi":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","title":"A Randomized Trial of the Effectiveness of Topical \u201cABH Gel\u201d (Ativan\u00ae, Benadryl\u00ae, Haldol\u00ae) vs. Placebo in Cancer Patients With Nausea","display_name":"A Randomized Trial of the Effectiveness of Topical \u201cABH Gel\u201d (Ativan\u00ae, Benadryl\u00ae, Haldol\u00ae) vs. Placebo in Cancer Patients With Nausea","publication_year":2014,"publication_date":"2014-05-02","ids":{"openalex":"https://openalex.org/W2020006363","doi":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","mag":"2020006363","pmid":"https://pubmed.ncbi.nlm.nih.gov/24793078"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpainsymman.2014.02.010","doi":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","pdf_url":"http://www.jpsmjournal.com/article/S0885392414001936/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jpsmjournal.com/article/S0885392414001936/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113584911","display_name":"Devon S. Fletcher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4390039382","display_name":"VCU Massey Comprehensive Cancer Center","ror":"https://ror.org/0173y3036","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184840846","https://openalex.org/I4390039382"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Devon S. Fletcher","raw_affiliation_strings":["Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA. Electronic address: dsfletcher@mcvh-vcu.edu","Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA. Electronic address: dsfletcher@mcvh-vcu.edu","institution_ids":["https://openalex.org/I4390039382"]},{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4390039382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019652298","display_name":"Patrick J. Coyne","orcid":"https://orcid.org/0000-0001-9517-3518","observed_orcids":["https://orcid.org/0000-0001-9517-3518"]},"institutions":[{"id":"https://openalex.org/I4390039382","display_name":"VCU Massey Comprehensive Cancer Center","ror":"https://ror.org/0173y3036","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184840846","https://openalex.org/I4390039382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick J. Coyne","raw_affiliation_strings":["Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4390039382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035578113","display_name":"Patricia W. Dodson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4390039382","display_name":"VCU Massey Comprehensive Cancer Center","ror":"https://ror.org/0173y3036","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184840846","https://openalex.org/I4390039382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia W. Dodson","raw_affiliation_strings":["Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4390039382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072826203","display_name":"Gwendolyn G. Parker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4390039382","display_name":"VCU Massey Comprehensive Cancer Center","ror":"https://ror.org/0173y3036","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184840846","https://openalex.org/I4390039382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gwendolyn G. Parker","raw_affiliation_strings":["Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4390039382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101462550","display_name":"Wen Wan","orcid":"https://orcid.org/0000-0002-2889-8460","observed_orcids":["https://orcid.org/0000-0002-2889-8460"]},"institutions":[{"id":"https://openalex.org/I4390039382","display_name":"VCU Massey Comprehensive Cancer Center","ror":"https://ror.org/0173y3036","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I184840846","https://openalex.org/I4390039382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen Wan","raw_affiliation_strings":["Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology & Palliative Care, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA","institution_ids":["https://openalex.org/I4390039382"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054848999","display_name":"Thomas J. Smith","orcid":"https://orcid.org/0000-0003-3040-6434","observed_orcids":["https://orcid.org/0000-0003-3040-6434"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas J. Smith","raw_affiliation_strings":["Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210164401"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5113584911"],"corresponding_institution_ids":["https://openalex.org/I4390039382"],"apc_list":{"value":4760,"currency":"USD","value_usd":4760},"apc_paid":null,"fwci":1.6506,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.83137775,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"48","issue":"5","first_page":"797","last_page":"803"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/topical-gel","display_name":"topical gel","score":0.531000018119812},{"id":"https://openalex.org/keywords/lorazepam","display_name":"lorazepam","score":0.8339999914169312},{"id":"https://openalex.org/keywords/diphenhydramine","display_name":"diphenhydramine","score":1.0},{"id":"https://openalex.org/keywords/haloperidol","display_name":"haloperidol","score":1.0},{"id":"https://openalex.org/keywords/non-inferiority","display_name":"non-inferiority","score":0.8560000061988831},{"id":"https://openalex.org/keywords/vomiting","display_name":"vomiting","score":0.6110000014305115},{"id":"https://openalex.org/keywords/drug-absorption","display_name":"drug absorption","score":0.5659999847412109},{"id":"https://openalex.org/keywords/placebo-controlled-comparison","display_name":"placebo comparison","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.9026380181312561},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7944022417068481},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7908706068992615},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.6718682646751404},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5639535188674927},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.42695194482803345},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.41154801845550537},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3033275902271271},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000932","descriptor_name":"Antiemetics","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000932","descriptor_name":"Antiemetics","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004155","descriptor_name":"Diphenhydramine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004155","descriptor_name":"Diphenhydramine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005782","descriptor_name":"Gels","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005782","descriptor_name":"Gels","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008140","descriptor_name":"Lorazepam","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008140","descriptor_name":"Lorazepam","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009325","descriptor_name":"Nausea","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009325","descriptor_name":"Nausea","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jpainsymman.2014.02.010","doi":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","pdf_url":"http://www.jpsmjournal.com/article/S0885392414001936/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},{"id":"pmid:24793078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24793078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pain and symptom management","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.jpainsymman.2014.02.010","doi":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2014.02.010","pdf_url":"http://www.jpsmjournal.com/article/S0885392414001936/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G6577331311","display_name":null,"funder_award_id":"PEP 10-174-01","funder_id":"https://openalex.org/F4320306095","funder_display_name":"American Cancer Society"}],"funders":[{"id":"https://openalex.org/F4320306095","display_name":"American Cancer Society","ror":"https://ror.org/02e463172"},{"id":"https://openalex.org/F4320311096","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2020006363.pdf","grobid_xml":"https://content.openalex.org/works/W2020006363.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W111055672","https://openalex.org/W159100949","https://openalex.org/W1547098353","https://openalex.org/W1977967074","https://openalex.org/W1983259118","https://openalex.org/W1987362941","https://openalex.org/W1993792063","https://openalex.org/W2029065444","https://openalex.org/W2030731302","https://openalex.org/W2055062581","https://openalex.org/W2076433366","https://openalex.org/W2085966447","https://openalex.org/W2087008767","https://openalex.org/W2094536157","https://openalex.org/W2098950572","https://openalex.org/W2101919110","https://openalex.org/W2108517568","https://openalex.org/W2121249260","https://openalex.org/W2121355626","https://openalex.org/W2127571716","https://openalex.org/W2148587601","https://openalex.org/W2150273386","https://openalex.org/W2158030636","https://openalex.org/W2335098354","https://openalex.org/W2526814824","https://openalex.org/W4232367328","https://openalex.org/W4235198105","https://openalex.org/W6604470936","https://openalex.org/W6728739855"],"related_works":["https://openalex.org/W4406986953","https://openalex.org/W2339615065","https://openalex.org/W1989398774","https://openalex.org/W159100949","https://openalex.org/W111055672","https://openalex.org/W2241254299","https://openalex.org/W2080350726","https://openalex.org/W2313261131","https://openalex.org/W2056606093","https://openalex.org/W3116530789"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}