{"id":"https://openalex.org/W2020002728","doi":"https://doi.org/10.1016/s1566-0702(03)00151-6","title":"Nerve growth factor regulates human choroidal, but not retinal, endothelial cell migration and proliferation","display_name":"Nerve growth factor regulates human choroidal, but not retinal, endothelial cell migration and proliferation","publication_year":2003,"publication_date":"2003-10-01","ids":{"openalex":"https://openalex.org/W2020002728","doi":"https://doi.org/10.1016/s1566-0702(03)00151-6","mag":"2020002728","pmid":"https://pubmed.ncbi.nlm.nih.gov/14614965"},"language":"en","primary_location":{"id":"doi:10.1016/s1566-0702(03)00151-6","doi":"https://doi.org/10.1016/s1566-0702(03)00151-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1566-0702(03)00151-6","pdf_url":null,"source":{"id":"https://openalex.org/S74113319","display_name":"Autonomic Neuroscience","issn_l":"1566-0702","issn":["1566-0702","1872-7484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autonomic Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054565442","display_name":"Jena J. Steinle","orcid":"https://orcid.org/0000-0002-7539-2892","observed_orcids":["https://orcid.org/0000-0002-7539-2892"]},"institutions":[{"id":"https://openalex.org/I173268674","display_name":"Texas A&M University System","ror":"https://ror.org/0034eay46","country_code":"US","type":"education","lineage":["https://openalex.org/I173268674"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jena J Steinle","raw_affiliation_strings":["Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA. jsteinle@siumed.edu","Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA. jsteinle@siumed.edu","institution_ids":["https://openalex.org/I173268674"]},{"raw_affiliation_string":"Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA","institution_ids":["https://openalex.org/I173268674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007631801","display_name":"Harris J. Granger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173268674","display_name":"Texas A&M University System","ror":"https://ror.org/0034eay46","country_code":"US","type":"education","lineage":["https://openalex.org/I173268674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harris J Granger","raw_affiliation_strings":["Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute and Department of Medical Physiology, College of Medicine, The Texas A&M University System Health Science Center, Temple, TX 76504, USA","institution_ids":["https://openalex.org/I173268674"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054565442"],"corresponding_institution_ids":["https://openalex.org/I173268674"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.9194,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.70336388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"108","issue":"1-2","first_page":"57","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.5820000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.5820000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.2969000041484833,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.022600000724196434,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nerve-growth-factor","display_name":"nerve growth factor","score":1.0},{"id":"https://openalex.org/keywords/choroidal-endothelial-cells","display_name":"choroidal endothelial cells","score":0.996999979019165},{"id":"https://openalex.org/keywords/retinal-endothelial-cells","display_name":"retinal endothelial cells","score":1.0},{"id":"https://openalex.org/keywords/endothelial-cell-migration","display_name":"endothelial cell migration","score":0.9929999709129333},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/erk1-2","display_name":"ERK1/2","score":0.9079999923706055},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.843999981880188},{"id":"https://openalex.org/keywords/src-kinase","display_name":"Src kinase","score":0.7319999933242798},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.7680000066757202},{"id":"https://openalex.org/keywords/mmp-2-9","display_name":"MMP2/9","score":0.8379999995231628},{"id":"https://openalex.org/keywords/vascular-remodeling","display_name":"vascular remodeling","score":0.7409999966621399},{"id":"https://openalex.org/keywords/sympathetic-denervation","display_name":"sympathetic denervation","score":0.9480000138282776},{"id":"https://openalex.org/keywords/choroid","display_name":"choroid","score":0.5080000162124634},{"id":"https://openalex.org/keywords/retina","display_name":"retina","score":0.8690000176429749}],"concepts":[{"id":"https://openalex.org/C2778423431","wikidata":"https://www.wikidata.org/wiki/Q417782","display_name":"Nerve growth factor","level":3,"score":0.7309664487838745},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5161298513412476},{"id":"https://openalex.org/C2777025900","wikidata":"https://www.wikidata.org/wiki/Q29725","display_name":"Vascular endothelial growth factor","level":3,"score":0.5131102800369263},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.49354875087738037},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.47550520300865173},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4672268331050873},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4630933105945587},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4554334580898285},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42320823669433594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3436071276664734},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.30620139837265015},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.2435389757156372},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21518832445144653},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07940730452537537},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002829","descriptor_name":"Choroid","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002829","descriptor_name":"Choroid","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002829","descriptor_name":"Choroid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020932","descriptor_name":"Nerve Growth Factor","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1566-0702(03)00151-6","doi":"https://doi.org/10.1016/s1566-0702(03)00151-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1566-0702(03)00151-6","pdf_url":null,"source":{"id":"https://openalex.org/S74113319","display_name":"Autonomic Neuroscience","issn_l":"1566-0702","issn":["1566-0702","1872-7484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autonomic Neuroscience","raw_type":"journal-article"},{"id":"pmid:14614965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14614965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autonomic neuroscience : basic & clinical","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1325589902","display_name":null,"funder_award_id":"R01 446221","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G311676816","display_name":null,"funder_award_id":"445991","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W146083735","https://openalex.org/W1917144620","https://openalex.org/W1979983164","https://openalex.org/W1996312276","https://openalex.org/W2042113277","https://openalex.org/W2050726791","https://openalex.org/W2071531606","https://openalex.org/W2084420410","https://openalex.org/W2086692188","https://openalex.org/W2088357680","https://openalex.org/W2121795027","https://openalex.org/W2130446433","https://openalex.org/W2142721310","https://openalex.org/W2158336844","https://openalex.org/W2165169594","https://openalex.org/W2171814302","https://openalex.org/W2284360226","https://openalex.org/W3105898142","https://openalex.org/W4211265319","https://openalex.org/W6680715167"],"related_works":["https://openalex.org/W2073860932","https://openalex.org/W2912309669","https://openalex.org/W2365928025","https://openalex.org/W2980784065","https://openalex.org/W1979499962","https://openalex.org/W2171814302","https://openalex.org/W2021393998","https://openalex.org/W2095655871","https://openalex.org/W2080272712","https://openalex.org/W2004047981"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}