{"id":"https://openalex.org/W2019951901","doi":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","title":"A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis","display_name":"A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2019951901","doi":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","mag":"2019951901","pmid":"https://pubmed.ncbi.nlm.nih.gov/12002729"},"language":"en","primary_location":{"id":"doi:10.1046/j.0022-0477.2001.01252.x","doi":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical &amp; Experimental Allergy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080457552","display_name":"Andrew M. Wilson","orcid":"https://orcid.org/0000-0002-5514-4867","observed_orcids":["https://orcid.org/0000-0002-5514-4867"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. M. Wilson","raw_affiliation_strings":["Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Scotland, UK","Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Scotland, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Scotland, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111785298","display_name":"Linda Orr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"L. C. Orr","raw_affiliation_strings":["Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111664878","display_name":"Wendy J. Coutie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W. J. R. Coutie","raw_affiliation_strings":["Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002323416","display_name":"Erika J Sims","orcid":"https://orcid.org/0000-0002-7898-0331","observed_orcids":["https://orcid.org/0000-0002-7898-0331"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. J. Sims","raw_affiliation_strings":["Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054519215","display_name":"Brian Jonathon Lipworth","orcid":"https://orcid.org/0000-0002-8140-2014","observed_orcids":["https://orcid.org/0000-0002-8140-2014"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"B. J. Lipworth","raw_affiliation_strings":["Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asthma & Allergy Research Group, Department of Clinical Pharmacology & Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5054519215"],"corresponding_institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"],"apc_list":{"value":4760,"currency":"USD","value_usd":4760},"apc_paid":null,"fwci":4.4555,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.94972452,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"32","issue":"1","first_page":"126","last_page":"132"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/fexofenadine","display_name":"fexofenadine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/montelukast","display_name":"montelukast","score":0.9990000128746033},{"id":"https://openalex.org/keywords/loratadine","display_name":"loratadine","score":1.0},{"id":"https://openalex.org/keywords/peak-inspiratory-flow","display_name":"peak inspiratory flow","score":0.8669999837875366},{"id":"https://openalex.org/keywords/nasal-symptoms","display_name":"nasal symptoms","score":0.8069999814033508},{"id":"https://openalex.org/keywords/grass-pollen","display_name":"grass pollen","score":0.6790000200271606},{"id":"https://openalex.org/keywords/leukotriene-receptor-antagonists","display_name":"leukotriene receptor antagonists","score":0.7630000114440918},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.4399999976158142}],"concepts":[{"id":"https://openalex.org/C2776711289","wikidata":"https://www.wikidata.org/wiki/Q415122","display_name":"Fexofenadine","level":2,"score":0.9605705142021179},{"id":"https://openalex.org/C2780734495","wikidata":"https://www.wikidata.org/wiki/Q424049","display_name":"Loratadine","level":2,"score":0.9239174127578735},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8345698118209839},{"id":"https://openalex.org/C2776322731","wikidata":"https://www.wikidata.org/wiki/Q417767","display_name":"Montelukast","level":3,"score":0.8183389902114868},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7086583375930786},{"id":"https://openalex.org/C2776880894","wikidata":"https://www.wikidata.org/wiki/Q324089","display_name":"Antihistamine","level":2,"score":0.5056617259979248},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.49793267250061035},{"id":"https://openalex.org/C2779923671","wikidata":"https://www.wikidata.org/wiki/Q199602","display_name":"Itching","level":2,"score":0.4858846068382263},{"id":"https://openalex.org/C2779303165","wikidata":"https://www.wikidata.org/wiki/Q417909","display_name":"Terfenadine","level":2,"score":0.4537331461906433},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3845823407173157},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.25441181659698486},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20986220240592957},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.08688518404960632},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000085","descriptor_name":"Acetates","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000085","descriptor_name":"Acetates","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000085","descriptor_name":"Acetates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003521","descriptor_name":"Cyclopropanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006109","descriptor_name":"Poaceae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009296","descriptor_name":"Nasal Cavity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011058","descriptor_name":"Pollen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012123","descriptor_name":"Pulmonary Ventilation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012882","descriptor_name":"Skin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013440","descriptor_name":"Sulfides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016037","descriptor_name":"Single-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016593","descriptor_name":"Terfenadine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D016593","descriptor_name":"Terfenadine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D016593","descriptor_name":"Terfenadine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D016593","descriptor_name":"Terfenadine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017336","descriptor_name":"Loratadine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D017336","descriptor_name":"Loratadine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D017336","descriptor_name":"Loratadine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018926","descriptor_name":"Anti-Allergic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D018926","descriptor_name":"Anti-Allergic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018926","descriptor_name":"Anti-Allergic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D020024","descriptor_name":"Leukotriene Antagonists","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D020024","descriptor_name":"Leukotriene Antagonists","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D020024","descriptor_name":"Leukotriene Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1046/j.0022-0477.2001.01252.x","doi":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.0022-0477.2001.01252.x","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical &amp; Experimental Allergy","raw_type":"journal-article"},{"id":"pmid:12002729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12002729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology","raw_type":"Clinical Trial"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire_cris_publications/de946aac-cae9-412d-9a7a-21dff6876e8c","doi":null,"is_oa":false,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/de946aac-cae9-412d-9a7a-21dff6876e8c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wilson, A M, Orr, L C, Coutie, W J R, Sims, E J & Lipworth, B J 2002, 'A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis', Clinical and Experimental Allergy, vol. 32, no. 1, pp. 126-32. https://doi.org/10.1046/j.0022-0477.2001.01252.x","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ueaeprints.uea.ac.uk:14721","doi":null,"is_oa":false,"landing_page_url":"https://ueaeprints.uea.ac.uk/id/eprint/14721/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400384","display_name":"UEA Digital Repository (University of East Anglia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1118541","host_organization_name":"University of East Anglia","host_organization_lineage":["https://openalex.org/I1118541"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1588576723","https://openalex.org/W1756057165","https://openalex.org/W1964226776","https://openalex.org/W1966348400","https://openalex.org/W1973319846","https://openalex.org/W1978387278","https://openalex.org/W1980421164","https://openalex.org/W1990121384","https://openalex.org/W1990841037","https://openalex.org/W1991717275","https://openalex.org/W1995203091","https://openalex.org/W2001450061","https://openalex.org/W2017009033","https://openalex.org/W2017512258","https://openalex.org/W2019856184","https://openalex.org/W2039983513","https://openalex.org/W2042418540","https://openalex.org/W2049841970","https://openalex.org/W2062878333","https://openalex.org/W2067070033","https://openalex.org/W2072883273","https://openalex.org/W2075007635","https://openalex.org/W2086363430","https://openalex.org/W2090477973","https://openalex.org/W2090625779","https://openalex.org/W2100552629","https://openalex.org/W2110026479","https://openalex.org/W2347756509","https://openalex.org/W2417605349","https://openalex.org/W2610900120","https://openalex.org/W4238800001","https://openalex.org/W4298034865"],"related_works":["https://openalex.org/W1988845032","https://openalex.org/W2106563551","https://openalex.org/W2016608951","https://openalex.org/W4411628401","https://openalex.org/W2076583793","https://openalex.org/W2183949087","https://openalex.org/W2048468038","https://openalex.org/W1989926090","https://openalex.org/W2051403856","https://openalex.org/W2063594663"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,121,160],"combination":[2,263],"of":[3,56,92,123,171,264],"montelukast":[4],"(ML)":[5],"and":[6,61,114,148,157,184,201,223,275],"loratadine":[7],"(LT)":[8],"has":[9,29],"previously":[10],"been":[11,30],"shown":[12,31],"to":[13,16,32,42,71,117,139,204,284,291],"be":[14,33],"superior":[15],"either":[17],"drug":[18],"alone":[19,49],"in":[20,198,270,278,293],"managing":[21],"seasonal":[22],"allergic":[23],"rhinitis":[24],"(SAR),":[25],"whilst":[26],"fexofenadine":[27],"(FEX)":[28],"better":[34],"than":[35],"LT":[36,46,249,269],"as":[37,167,256,261],"monotherapy.":[38],"OBJECTIVES:":[39],"We":[40],"wished":[41],"compare":[43],"ML":[44,103,247,267,287],"+":[45,104,248,268],"vs.":[47],"FEX":[48,99,232,244,255,292],"for":[50,143,187,210],"effects":[51],"on":[52],"daily":[53,94,158,254,266],"measurements":[54],"(am/pm)":[55],"peak":[57,273],"inspiratory":[58],"flow":[59,274],"(PIF)":[60],"symptoms.":[62],"METHODS:":[63],"Thirty-seven":[64],"patients":[65],"with":[66,96,207],"SAR":[67],"(skin":[68],"prick":[69],"positive":[70],"grass":[72,86],"pollen)":[73],"were":[74,175,191],"randomised":[75,119],"into":[76],"a":[77,109,168],"single-blind,":[78],"double-dummy":[79],"placebo":[80,112,206],"(PL)-controlled":[81],"cross-over":[82],"study":[83],"during":[84],"the":[85,182,217,262],"pollen":[87],"season,":[88],"comparing":[89],"2":[90],"weeks":[91],"once":[93,265],"treatment":[95,219],"(a)":[97],"120mg":[98],"or":[100],"(b)":[101],"10mg":[102,105],"LT.":[106],"There":[107,174,190],"was":[108,130,165,258],"7-10":[110],"day":[111],"run-in":[113,183],"washout":[115,185],"prior":[116],"each":[118],"treatment.":[120],"average":[122],"am/pm":[124],"PIF":[125,202],"(the":[126],"primary":[127],"outcome":[128],"variable)":[129],"analysed.":[131],"Patients":[132],"recorded":[133],"their":[134],"symptom":[135,163],"scores":[136],"(from":[137],"0":[138],"3)":[140],"twice":[141],"daily,":[142],"nasal":[144,162,239,272],"blockage,":[145],"discharge,":[146],"itching":[147],"sneezing":[149],"with;":[150],"total":[151,161,238],"eye":[152],"symptoms,":[153],"ocular":[154],"cromoglycate":[155],"use,":[156],"activity.":[159],"score":[164],"calculated":[166],"composite":[169],"(out":[170],"24).":[172],"RESULTS:":[173],"no":[176,214],"significant":[177,192],"differences":[178,215],"between":[179,216],"baselines":[180],"after":[181],"placebos":[186],"any":[188],"variables.":[189],"(P":[193],"<":[194],"0.05,":[195],"Bonferroni)":[196],"improvements":[197],"all":[199,211],"symptoms":[200,277],"compared":[203],"pooled":[205],"both":[208],"treatments":[209],"end-points,":[212],"but":[213],"two":[218],"regimes":[220],"(as":[221],"means":[222],"within-treatment":[224],"95%":[225],"confidence":[226],"intervals):":[227],"PIF:":[228],"PL":[229,241],"102":[230],"(98-107),":[231],"111":[233],"(107-116),":[234],"ML+LT":[235],"113":[236],"(109-118);":[237],"symptoms:":[240],"7.4":[242],"(6.7-2.0),":[243],"5.0":[245],"(4.3-5.7),":[246],"4.0":[250],"(3.3-4.7).":[251],"CONCLUSIONS:":[252],"Once":[253],"monotherapy":[257],"equally":[259],"effective":[260],"improving":[271],"controlling":[276],"SAR.":[279,294],"Further":[280],"studies":[281],"are":[282],"indicated":[283],"assess":[285],"whether":[286],"confers":[288],"additional":[289],"benefits":[290]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}