{"id":"https://openalex.org/W2019928465","doi":"https://doi.org/10.1002/neu.20242","title":"Overview of retinoid metabolism and function","display_name":"Overview of retinoid metabolism and function","publication_year":2006,"publication_date":"2006-05-10","ids":{"openalex":"https://openalex.org/W2019928465","doi":"https://doi.org/10.1002/neu.20242","mag":"2019928465","pmid":"https://pubmed.ncbi.nlm.nih.gov/16688755"},"language":"en","primary_location":{"id":"doi:10.1002/neu.20242","doi":"https://doi.org/10.1002/neu.20242","is_oa":false,"landing_page_url":"https://doi.org/10.1002/neu.20242","pdf_url":null,"source":{"id":"https://openalex.org/S68990794","display_name":"Journal of Neurobiology","issn_l":"0022-3034","issn":["0022-3034","1097-4695"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurobiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062057544","display_name":"Rune Blomhoff","orcid":"https://orcid.org/0000-0001-7329-3615","observed_orcids":["https://orcid.org/0000-0001-7329-3615"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Rune Blomhoff","raw_affiliation_strings":["Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. rune.blomhoff@medisin.uio.no","Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. rune.blomhoff@medisin.uio.no","institution_ids":["https://openalex.org/I184942183"]},{"raw_affiliation_string":"Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo , Oslo , Norway ,","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084860151","display_name":"Heidi Kiil Blomhoff","orcid":"https://orcid.org/0000-0002-8537-5439","observed_orcids":["https://orcid.org/0000-0002-8537-5439"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Heidi Kiil Blomhoff","raw_affiliation_strings":["\u00a7 Department of Medical Biochemistry, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7 Department of Medical Biochemistry, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062057544"],"corresponding_institution_ids":["https://openalex.org/I184942183"],"apc_list":null,"apc_paid":null,"fwci":3.7052,"has_fulltext":false,"cited_by_count":946,"citation_normalized_percentile":{"value":0.96676205,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"66","issue":"7","first_page":"606","last_page":"630"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinoids","display_name":"retinoids","score":0.8700000047683716},{"id":"https://openalex.org/keywords/vitamin-a","display_name":"vitamin A","score":0.8460000157356262},{"id":"https://openalex.org/keywords/vitamin-a-metabolism","display_name":"vitamin A metabolism","score":0.9229999780654907},{"id":"https://openalex.org/keywords/all-trans-retinoic-acid","display_name":"all-trans retinoic acid","score":0.9760000109672546},{"id":"https://openalex.org/keywords/nuclear-receptors","display_name":"nuclear receptors","score":0.7279999852180481},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.7160000205039978},{"id":"https://openalex.org/keywords/non-coding-rna-regulation","display_name":"non-coding RNA regulation","score":0.746999979019165},{"id":"https://openalex.org/keywords/opsin","display_name":"opsin","score":0.5659999847412109},{"id":"https://openalex.org/keywords/11-cis-retinal","display_name":"11-cis-retinal","score":0.8870000243186951},{"id":"https://openalex.org/keywords/visual-cycle","display_name":"visual cycle","score":0.8080000281333923},{"id":"https://openalex.org/keywords/phototransduction","display_name":"phototransduction","score":0.9440000057220459},{"id":"https://openalex.org/keywords/retinol-esterification","display_name":"retinol esterification","score":0.796999990940094},{"id":"https://openalex.org/keywords/retinol-oxidation","display_name":"retinol oxidation","score":0.7710000276565552},{"id":"https://openalex.org/keywords/retinoid-binding-proteins","display_name":"retinoid-binding proteins","score":0.5979999899864197},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.902999997138977},{"id":"https://openalex.org/keywords/vision","display_name":"vision","score":0.6669999957084656},{"id":"https://openalex.org/keywords/retinal-disease","display_name":"retinal disease","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8428515195846558},{"id":"https://openalex.org/C131667965","wikidata":"https://www.wikidata.org/wiki/Q445081","display_name":"Visual phototransduction","level":3,"score":0.6913487911224365},{"id":"https://openalex.org/C2781121885","wikidata":"https://www.wikidata.org/wiki/Q425517","display_name":"Retinoic acid","level":3,"score":0.6847209930419922},{"id":"https://openalex.org/C63932345","wikidata":"https://www.wikidata.org/wiki/Q422500","display_name":"Nuclear receptor","level":4,"score":0.6295742392539978},{"id":"https://openalex.org/C2775954498","wikidata":"https://www.wikidata.org/wiki/Q420418","display_name":"Retinoid","level":4,"score":0.5364354848861694},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.53205806016922},{"id":"https://openalex.org/C30028475","wikidata":"https://www.wikidata.org/wiki/Q24785022","display_name":"Opsin","level":4,"score":0.5240221619606018},{"id":"https://openalex.org/C162253465","wikidata":"https://www.wikidata.org/wiki/Q18031338","display_name":"Retinoid X receptor gamma","level":5,"score":0.5220180153846741},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5067742466926575},{"id":"https://openalex.org/C2909445175","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinaldehyde","level":4,"score":0.4856325685977936},{"id":"https://openalex.org/C202033177","wikidata":"https://www.wikidata.org/wiki/Q423107","display_name":"Rhodopsin","level":3,"score":0.42120885848999023},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4159458875656128},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.41378942131996155},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2370712161064148}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012176","descriptor_name":"Retinoids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012176","descriptor_name":"Retinoids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/neu.20242","doi":"https://doi.org/10.1002/neu.20242","is_oa":false,"landing_page_url":"https://doi.org/10.1002/neu.20242","pdf_url":null,"source":{"id":"https://openalex.org/S68990794","display_name":"Journal of Neurobiology","issn_l":"0022-3034","issn":["0022-3034","1097-4695"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurobiology","raw_type":"journal-article"},{"id":"pmid:16688755","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16688755","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurobiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":200,"referenced_works":["https://openalex.org/W13928267","https://openalex.org/W173017759","https://openalex.org/W336308498","https://openalex.org/W1224318197","https://openalex.org/W1480249646","https://openalex.org/W1490537199","https://openalex.org/W1501843431","https://openalex.org/W1527331090","https://openalex.org/W1527976882","https://openalex.org/W1530829742","https://openalex.org/W1536846296","https://openalex.org/W1538483334","https://openalex.org/W1542896047","https://openalex.org/W1552108793","https://openalex.org/W1568773554","https://openalex.org/W1570165358","https://openalex.org/W1583068153","https://openalex.org/W1598136768","https://openalex.org/W1621475458","https://openalex.org/W1773215920","https://openalex.org/W1838818166","https://openalex.org/W1854733189","https://openalex.org/W1892704773","https://openalex.org/W1898529555","https://openalex.org/W1900037177","https://openalex.org/W1918723691","https://openalex.org/W1923407962","https://openalex.org/W1939266489","https://openalex.org/W1951782498","https://openalex.org/W1962859616","https://openalex.org/W1966605340","https://openalex.org/W1966631604","https://openalex.org/W1966893980","https://openalex.org/W1967124221","https://openalex.org/W1970882296","https://openalex.org/W1971045517","https://openalex.org/W1971624992","https://openalex.org/W1971989159","https://openalex.org/W1972115931","https://openalex.org/W1972258703","https://openalex.org/W1973672071","https://openalex.org/W1974161676","https://openalex.org/W1975354953","https://openalex.org/W1976405146","https://openalex.org/W1978628739","https://openalex.org/W1980628720","https://openalex.org/W1984271324","https://openalex.org/W1984495434","https://openalex.org/W1985766599","https://openalex.org/W1985774463","https://openalex.org/W1986681749","https://openalex.org/W1989349753","https://openalex.org/W1989965266","https://openalex.org/W1993277813","https://openalex.org/W1994591003","https://openalex.org/W1996304093","https://openalex.org/W1999170657","https://openalex.org/W1999669689","https://openalex.org/W2000863347","https://openalex.org/W2000909623","https://openalex.org/W2001068122","https://openalex.org/W2001890593","https://openalex.org/W2002992087","https://openalex.org/W2003366894","https://openalex.org/W2003697552","https://openalex.org/W2003877984","https://openalex.org/W2004015295","https://openalex.org/W2004745065","https://openalex.org/W2004798737","https://openalex.org/W2005096677","https://openalex.org/W2005229619","https://openalex.org/W2008153060","https://openalex.org/W2008917724","https://openalex.org/W2014591899","https://openalex.org/W2016392505","https://openalex.org/W2019631619","https://openalex.org/W2020229839","https://openalex.org/W2024153033","https://openalex.org/W2024822097","https://openalex.org/W2025631499","https://openalex.org/W2026526608","https://openalex.org/W2027352561","https://openalex.org/W2028236635","https://openalex.org/W2028924333","https://openalex.org/W2029911510","https://openalex.org/W2031403549","https://openalex.org/W2033154232","https://openalex.org/W2035246287","https://openalex.org/W2038006194","https://openalex.org/W2040470926","https://openalex.org/W2040497188","https://openalex.org/W2041270901","https://openalex.org/W2042896578","https://openalex.org/W2043467656","https://openalex.org/W2043566799","https://openalex.org/W2047041368","https://openalex.org/W2047508855","https://openalex.org/W2049259578","https://openalex.org/W2049791242","https://openalex.org/W2050102433","https://openalex.org/W2050724322","https://openalex.org/W2052257773","https://openalex.org/W2053520712","https://openalex.org/W2053833990","https://openalex.org/W2054216132","https://openalex.org/W2054564135","https://openalex.org/W2057228368","https://openalex.org/W2057228996","https://openalex.org/W2059290408","https://openalex.org/W2059350441","https://openalex.org/W2059506882","https://openalex.org/W2060034125","https://openalex.org/W2061997861","https://openalex.org/W2064333692","https://openalex.org/W2066823591","https://openalex.org/W2066856908","https://openalex.org/W2070392447","https://openalex.org/W2071230039","https://openalex.org/W2072233737","https://openalex.org/W2073020869","https://openalex.org/W2073509861","https://openalex.org/W2074223532","https://openalex.org/W2076625483","https://openalex.org/W2081524603","https://openalex.org/W2085235805","https://openalex.org/W2085284028","https://openalex.org/W2085511966","https://openalex.org/W2085760990","https://openalex.org/W2086257051","https://openalex.org/W2086345206","https://openalex.org/W2086403021","https://openalex.org/W2087116846","https://openalex.org/W2089189711","https://openalex.org/W2090260875","https://openalex.org/W2091385674","https://openalex.org/W2093805751","https://openalex.org/W2094371797","https://openalex.org/W2094643713","https://openalex.org/W2095013953","https://openalex.org/W2096411979","https://openalex.org/W2096547256","https://openalex.org/W2098940343","https://openalex.org/W2099556926","https://openalex.org/W2104030002","https://openalex.org/W2107195891","https://openalex.org/W2107523109","https://openalex.org/W2108068214","https://openalex.org/W2113943095","https://openalex.org/W2114263087","https://openalex.org/W2115261526","https://openalex.org/W2116718309","https://openalex.org/W2118842826","https://openalex.org/W2119476491","https://openalex.org/W2122146446","https://openalex.org/W2122256734","https://openalex.org/W2125429880","https://openalex.org/W2125755853","https://openalex.org/W2126005618","https://openalex.org/W2129387993","https://openalex.org/W2129450503","https://openalex.org/W2132335701","https://openalex.org/W2132971990","https://openalex.org/W2133380542","https://openalex.org/W2134390605","https://openalex.org/W2137590082","https://openalex.org/W2140865108","https://openalex.org/W2141063844","https://openalex.org/W2141478391","https://openalex.org/W2142877387","https://openalex.org/W2143241514","https://openalex.org/W2144603414","https://openalex.org/W2145951364","https://openalex.org/W2148070218","https://openalex.org/W2148271975","https://openalex.org/W2149940976","https://openalex.org/W2151164511","https://openalex.org/W2154503677","https://openalex.org/W2157319045","https://openalex.org/W2163803523","https://openalex.org/W2164579477","https://openalex.org/W2164648160","https://openalex.org/W2167269900","https://openalex.org/W2167877064","https://openalex.org/W2173037214","https://openalex.org/W2184107901","https://openalex.org/W2189330121","https://openalex.org/W2294164487","https://openalex.org/W2318278041","https://openalex.org/W2334286404","https://openalex.org/W2398471043","https://openalex.org/W2400775276","https://openalex.org/W2415983846","https://openalex.org/W2418084145","https://openalex.org/W2501009041","https://openalex.org/W2570010716","https://openalex.org/W2735280994","https://openalex.org/W3023305311","https://openalex.org/W4211095275","https://openalex.org/W4247105253","https://openalex.org/W6712987671"],"related_works":["https://openalex.org/W2115830858","https://openalex.org/W4255599272","https://openalex.org/W188338954","https://openalex.org/W2362473391","https://openalex.org/W2102715438","https://openalex.org/W1547641089","https://openalex.org/W3012490444","https://openalex.org/W2140522238","https://openalex.org/W2144264206","https://openalex.org/W1812139864"],"abstract_inverted_index":{"Retinoids":[0],"(vitamin":[1],"A)":[2],"are":[3,88,100,208],"crucial":[4],"for":[5],"most":[6,63],"forms":[7],"of":[8,33,42,49,64,69,77,84,96,98,130,165,180,186,198,212,221,237,248,261],"life.":[9,268],"In":[10,104,135],"chordates,":[11],"they":[12],"have":[13,168,201],"important":[14],"roles":[15],"in":[16,31,210,219,234,253,259],"the":[17,75,157],"developing":[18],"nervous":[19],"system":[20],"and":[21,23,38,171,192,196,240,258,265],"notochord":[22],"many":[24,174],"other":[25],"embryonic":[26,256],"structures,":[27],"as":[28,30,125,216,218,250],"well":[29,217],"maintenance":[32],"epithelial":[34],"surfaces,":[35],"immune":[36],"competence,":[37],"reproduction.":[39],"The":[40,67,151],"ability":[41],"all-trans":[43,70,187,190,193,199,222],"retinoic":[44,71,91,194,223],"acid":[45,224],"to":[46,55,61,109,115,149,173,189,225],"regulate":[47],"expression":[48],"several":[50,211],"hundred":[51],"genes":[52,162],"through":[53],"binding":[54,206],"nuclear":[56,226],"transcription":[57,79],"factors":[58],"is":[59,112,138,147,154],"believed":[60],"mediate":[62],"these":[65,213],"functions.":[66],"role":[68],"may":[72],"extend":[73],"beyond":[74],"regulation":[76],"gene":[78],"because":[80],"a":[81,141],"large":[82],"number":[83],"noncoding":[85],"RNAs":[86],"also":[87,101],"regulated":[89],"by":[90,140],"acid.":[92],"Additionally,":[93],"extra-nuclear":[94],"mechanisms":[95],"action":[97],"retinoids":[99,249],"being":[102],"identified.":[103],"organisms":[105],"ranging":[106],"from":[107],"prokaryotes":[108],"humans,":[110],"retinal":[111,176,191],"covalently":[113],"linked":[114,172],"G":[116],"protein-coupled":[117],"transmembrane":[118],"receptors":[119,123],"called":[120],"opsins.":[121],"These":[122],"function":[124],"light-driven":[126],"ion":[127],"pumps,":[128],"mediators":[129],"phototaxis,":[131],"or":[132],"photosensory":[133],"pigments.":[134],"vertebrates":[136],"phototransduction":[137],"initiated":[139],"photochemical":[142],"reaction":[143],"where":[144],"opsin-bound":[145],"11-cis-retinal":[146],"isomerized":[148],"all-trans-retinal.":[150],"photosensitive":[152],"receptor":[153],"restored":[155],"via":[156],"retinoid":[158,238],"visual":[159],"cycle.":[160],"Multiple":[161],"encoding":[163],"components":[164],"this":[166],"cycle":[167],"been":[169,202,232],"identified":[170],"human":[175],"diseases.":[177],"Central":[178],"aspects":[179],"vitamin":[181],"A":[182],"absorption,":[183],"enzymatic":[184,214],"oxidation":[185],"retinol":[188,200],"acid,":[195],"esterification":[197],"clarified.":[203],"Furthermore,":[204],"specific":[205],"proteins":[207],"involved":[209],"processes":[215],"delivery":[220],"receptors.":[227],"Thus,":[228],"substantial":[229],"progress":[230],"has":[231,244],"made":[233],"our":[235,246],"understanding":[236],"metabolism":[239],"function.":[241],"This":[242],"insight":[243],"improved":[245],"view":[247],"critical":[251],"molecules":[252],"vision,":[254],"normal":[255],"development,":[257],"control":[260],"cellular":[262],"growth,":[263],"differentiation,":[264],"death":[266],"throughout":[267]},"counts_by_year":[{"year":2026,"cited_by_count":35},{"year":2025,"cited_by_count":37},{"year":2024,"cited_by_count":33},{"year":2023,"cited_by_count":39},{"year":2022,"cited_by_count":35},{"year":2021,"cited_by_count":51},{"year":2020,"cited_by_count":48},{"year":2019,"cited_by_count":49},{"year":2018,"cited_by_count":36},{"year":2017,"cited_by_count":55},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":62},{"year":2014,"cited_by_count":44},{"year":2013,"cited_by_count":81},{"year":2012,"cited_by_count":55}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}