{"id":"https://openalex.org/W2019916062","doi":"https://doi.org/10.1038/2071102a0","title":"Cathepsin A in Nutritional and Hereditary Muscular Dystrophy","display_name":"Cathepsin A in Nutritional and Hereditary Muscular Dystrophy","publication_year":1965,"publication_date":"1965-09-01","ids":{"openalex":"https://openalex.org/W2019916062","doi":"https://doi.org/10.1038/2071102a0","mag":"2019916062","pmid":"https://pubmed.ncbi.nlm.nih.gov/5866314"},"language":"en","primary_location":{"id":"doi:10.1038/2071102a0","doi":"https://doi.org/10.1038/2071102a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/2071102a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060769989","display_name":"Arthur A. Iodice","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260186","display_name":"Institut f\u00fcr Muskuloskelettale Medizin","ror":"https://ror.org/03cmqx484","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405260186","https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. A. IODICE","raw_affiliation_strings":["Institute for Muscle Disease, Inc., New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Muscle Disease, Inc., New York","institution_ids":["https://openalex.org/I4405260186"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000063008","display_name":"Irwin M. Weinstock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260186","display_name":"Institut f\u00fcr Muskuloskelettale Medizin","ror":"https://ror.org/03cmqx484","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405260186","https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I. M. WEINSTOCK","raw_affiliation_strings":["Institute for Muscle Disease, Inc., New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Muscle Disease, Inc., New York","institution_ids":["https://openalex.org/I4405260186"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405260186"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":0.4055,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.5461734,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"207","issue":"5001","first_page":"1102","last_page":"1102"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cathepsin-a","display_name":"cathepsin A","score":1.0},{"id":"https://openalex.org/keywords/muscular-dystrophy","display_name":"muscular dystrophy","score":0.9210000038146973},{"id":"https://openalex.org/keywords/hereditary-muscular-dystrophy","display_name":"hereditary muscular dystrophy","score":0.8519999980926514},{"id":"https://openalex.org/keywords/nutritional-muscular-dystrophy","display_name":"nutritional muscular dystrophy","score":0.9139999747276306},{"id":"https://openalex.org/keywords/acid-hydrolases","display_name":"acid hydrolases","score":0.9340000152587891},{"id":"https://openalex.org/keywords/skeletal-muscle-atrophy","display_name":"skeletal muscle atrophy","score":0.6850000023841858},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.9520000219345093},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C2779764123","wikidata":"https://www.wikidata.org/wiki/Q7972881","display_name":"Wasting","level":2,"score":0.9079731106758118},{"id":"https://openalex.org/C2779030066","wikidata":"https://www.wikidata.org/wiki/Q1137767","display_name":"Muscular dystrophy","level":2,"score":0.7582182884216309},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.724341630935669},{"id":"https://openalex.org/C96942376","wikidata":"https://www.wikidata.org/wiki/Q21130714","display_name":"Catabolism","level":3,"score":0.6900530457496643},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5578048229217529},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.46259966492652893},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4541941285133362},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4180494546890259},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4043310284614563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3792620897293091},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30645835399627686}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002403","descriptor_name":"Cathepsins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009136","descriptor_name":"Muscular Dystrophies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011200","descriptor_name":"Poultry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/2071102a0","doi":"https://doi.org/10.1038/2071102a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/2071102a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:5866314","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5866314","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.504800021648407,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W61895332","https://openalex.org/W68404716","https://openalex.org/W1511235377","https://openalex.org/W1665485334","https://openalex.org/W1775749144","https://openalex.org/W1994091026","https://openalex.org/W2016472386","https://openalex.org/W2079658804","https://openalex.org/W2088696986","https://openalex.org/W2223155177","https://openalex.org/W2292257168","https://openalex.org/W2312308961","https://openalex.org/W2325685548","https://openalex.org/W4241864365"],"related_works":["https://openalex.org/W2088696986","https://openalex.org/W2403764905","https://openalex.org/W1981062761","https://openalex.org/W4231374946","https://openalex.org/W2080752392","https://openalex.org/W2154830076","https://openalex.org/W2745263756","https://openalex.org/W2047538367","https://openalex.org/W2065391167","https://openalex.org/W2409043165"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}