{"id":"https://openalex.org/W2019903718","doi":"https://doi.org/10.1109/isbi.2014.6867851","title":"Automatic learning-based selection of beam angles in radiation therapy of lung cancer","display_name":"Automatic learning-based selection of beam angles in radiation therapy of lung cancer","publication_year":2014,"publication_date":"2014-04-01","ids":{"openalex":"https://openalex.org/W2019903718","doi":"https://doi.org/10.1109/isbi.2014.6867851","mag":"2019903718"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2014.6867851","doi":"https://doi.org/10.1109/isbi.2014.6867851","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2014.6867851","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084959917","display_name":"Guy Amit","orcid":"https://orcid.org/0000-0002-5987-4402","observed_orcids":["https://orcid.org/0000-0002-5987-4402"]},"institutions":[{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Guy Amit","raw_affiliation_strings":["Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018452517","display_name":"Thomas G. Purdie","orcid":"https://orcid.org/0000-0003-4176-8457","observed_orcids":["https://orcid.org/0000-0003-4176-8457"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Thomas G. Purdie","raw_affiliation_strings":["Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029007864","display_name":"Alex Levinshtein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alex Levinshtein","raw_affiliation_strings":["Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010067099","display_name":"Andrew J. Hope","orcid":"https://orcid.org/0000-0001-6793-2863","observed_orcids":["https://orcid.org/0000-0001-6793-2863"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Andrew J. Hope","raw_affiliation_strings":["Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110242785","display_name":"Patricia E Lindsay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Patricia Lindsay","raw_affiliation_strings":["Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008048551","display_name":"David Anthony Jaffray","orcid":"https://orcid.org/0000-0001-7378-7543","observed_orcids":["https://orcid.org/0000-0001-7378-7543"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802654988","display_name":"Princess Margaret Cancer Centre","ror":"https://ror.org/03zayce58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2802654988"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"David A. Jaffray","raw_affiliation_strings":["Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I2802654988"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032186518","display_name":"Vladim\u00edr Pekar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126238","display_name":"Philips (Canada)","ror":"https://ror.org/0326cx138","country_code":"CA","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210126238"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Vladimir Pekar","raw_affiliation_strings":["Philips Healthcare, Markham, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philips Healthcare, Markham, ON, Canada","institution_ids":["https://openalex.org/I4210126238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7106,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.80365606,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beam-angle-selection","display_name":"beam angle selection","score":0.8510000109672546},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.8769999742507935},{"id":"https://openalex.org/keywords/external-beam-radiotherapy","display_name":"external beam radiotherapy","score":0.8610000014305115},{"id":"https://openalex.org/keywords/automated-treatment-planning","display_name":"automated treatment planning","score":0.6890000104904175},{"id":"https://openalex.org/keywords/random-forest-regression","display_name":"random forest regression","score":0.8500000238418579},{"id":"https://openalex.org/keywords/normal-tissue-sparing","display_name":"normal tissue sparing","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6456677317619324},{"id":"https://openalex.org/C168834538","wikidata":"https://www.wikidata.org/wiki/Q3705329","display_name":"Beam (structure)","level":2,"score":0.6033214330673218},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.5437350273132324},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.542667806148529},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5321012735366821},{"id":"https://openalex.org/C3020003399","wikidata":"https://www.wikidata.org/wiki/Q3070621","display_name":"External beam radiation","level":3,"score":0.49619704484939575},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.4803920388221741},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4672037959098816},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.45564115047454834},{"id":"https://openalex.org/C2778476105","wikidata":"https://www.wikidata.org/wiki/Q628539","display_name":"Workload","level":2,"score":0.43993744254112244},{"id":"https://openalex.org/C2780069185","wikidata":"https://www.wikidata.org/wiki/Q7977945","display_name":"Equivalence (formal languages)","level":2,"score":0.43313807249069214},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3490784168243408},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18721306324005127},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1776614487171173},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17473390698432922},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1425010859966278},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.11785739660263062},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2014.6867851","doi":"https://doi.org/10.1109/isbi.2014.6867851","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2014.6867851","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1971575590","https://openalex.org/W1997523098","https://openalex.org/W2002571443","https://openalex.org/W2006626394","https://openalex.org/W2014039164","https://openalex.org/W2014077750","https://openalex.org/W2040216858","https://openalex.org/W2057309390","https://openalex.org/W2092401997","https://openalex.org/W2166355093","https://openalex.org/W2911964244"],"related_works":["https://openalex.org/W2063094280","https://openalex.org/W2167384549","https://openalex.org/W2258344410","https://openalex.org/W2085798191","https://openalex.org/W4406301985","https://openalex.org/W7126235495","https://openalex.org/W4410561447","https://openalex.org/W4404883376","https://openalex.org/W1992883091","https://openalex.org/W4400267767"],"abstract_inverted_index":{"The":[0,98],"treatment":[1,21,75],"of":[2,13,22,48,84],"lung":[3],"cancer":[4],"using":[5],"external":[6],"beam":[7,16,30,39,59],"radiation":[8,15,90],"requires":[9],"an":[10,28,65],"optimal":[11],"selection":[12,31],"the":[14,36,74,82,88,94,109],"directions":[17],"to":[18,57,93],"avoid":[19],"unnecessarily":[20],"normal":[23],"healthy":[24],"tissues.":[25],"We":[26,62,77],"introduce":[27],"automated":[29],"method,":[32],"based":[33],"on":[34],"learning":[35],"relations":[37],"between":[38],"angles":[40],"and":[41,72,87],"anatomical":[42],"features.":[43],"Using":[44],"a":[45,53,103],"large":[46],"dataset":[47],"clinical":[49,105],"plans,":[50],"we":[51],"train":[52],"random":[54],"forest":[55],"regressor":[56],"predict":[58],"angle":[60],"likelihood.":[61],"then":[63],"use":[64],"optimization":[66],"procedure":[67],"that":[68],"incorporates":[69],"inter-beam":[70],"dependencies":[71],"selects":[73],"beams.":[76],"present":[78],"validation":[79],"results,":[80],"demonstrating":[81],"equivalence":[83],"automatically-selected":[85],"beams":[86],"derived":[89],"therapy":[91],"plans":[92],"clinical,":[95],"manually-planned,":[96],"ground-truth.":[97],"proposed":[99],"method":[100],"may":[101],"be":[102],"useful":[104],"tool":[106],"for":[107],"reducing":[108],"manual":[110],"planning":[111],"workload,":[112],"while":[113],"sustaining":[114],"plan":[115],"quality.":[116]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}