{"id":"https://openalex.org/W2019892276","doi":"https://doi.org/10.1099/00221287-121-2-495","title":"Phosphatidylinositol-degrading Enzymes in the Cellular Slime Mould Dictyostelium discoideum","display_name":"Phosphatidylinositol-degrading Enzymes in the Cellular Slime Mould Dictyostelium discoideum","publication_year":1980,"publication_date":"1980-12-01","ids":{"openalex":"https://openalex.org/W2019892276","doi":"https://doi.org/10.1099/00221287-121-2-495","mag":"2019892276"},"language":"en","primary_location":{"id":"doi:10.1099/00221287-121-2-495","doi":"https://doi.org/10.1099/00221287-121-2-495","is_oa":false,"landing_page_url":"https://doi.org/10.1099/00221287-121-2-495","pdf_url":null,"source":{"id":"https://openalex.org/S196799759","display_name":"Microbiology","issn_l":"1350-0872","issn":["1350-0872","1465-2080"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056553379","display_name":"Robin F. Irvine","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. F. IRVINE","raw_affiliation_strings":["Department of Biochemistry, ARC Institute of Animal Physiology, Babraham, Cambridge CB2 4AT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, ARC Institute of Animal Physiology, Babraham, Cambridge CB2 4AT","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017453864","display_name":"Amber Letcher","orcid":"https://orcid.org/0000-0001-8993-0834","observed_orcids":["https://orcid.org/0000-0001-8993-0834"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. J. LETCHER","raw_affiliation_strings":["Department of Biochemistry, ARC Institute of Animal Physiology, Babraham, Cambridge CB2 4AT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, ARC Institute of Animal Physiology, Babraham, Cambridge CB2 4AT","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008629180","display_name":"Peter Brophy","orcid":"https://orcid.org/0000-0002-0262-9545","observed_orcids":["https://orcid.org/0000-0002-0262-9545"]},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. J. BROPHY","raw_affiliation_strings":["Department of Biochemistry, University of Stirling, Stirling FK9 4LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Stirling, Stirling FK9 4LA","institution_ids":["https://openalex.org/I12093191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027434411","display_name":"MICHAEL J. NORTH","orcid":"https://orcid.org/0000-0002-6668-5503","observed_orcids":["https://orcid.org/0000-0002-6668-5503"]},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. J. NORTH","raw_affiliation_strings":["Department of Biochemistry, University of Stirling, Stirling FK9 4LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Stirling, Stirling FK9 4LA","institution_ids":["https://openalex.org/I12093191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6556,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.5937842,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"121","issue":"2","first_page":"495","last_page":"497"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13362","display_name":"Slime Mold and Myxomycetes Research","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycerophosphoinositol","display_name":"glycerophosphoinositol","score":0.9350000023841858},{"id":"https://openalex.org/keywords/myxamoebae","display_name":"myxamoebae","score":0.824999988079071},{"id":"https://openalex.org/keywords/dictyostelium-discoideum","display_name":"Dictyostelium discoideum","score":0.9660000205039978},{"id":"https://openalex.org/keywords/phospholipid-hydrolysis","display_name":"phospholipid hydrolysis","score":0.8410000205039978}],"concepts":[{"id":"https://openalex.org/C2775969001","wikidata":"https://www.wikidata.org/wiki/Q134351","display_name":"Dictyostelium discoideum","level":3,"score":0.9866522550582886},{"id":"https://openalex.org/C2780610907","wikidata":"https://www.wikidata.org/wiki/Q2273248","display_name":"Phosphatidylinositol","level":3,"score":0.8257088661193848},{"id":"https://openalex.org/C33682779","wikidata":"https://www.wikidata.org/wiki/Q949817","display_name":"Slime mold","level":2,"score":0.8077479600906372},{"id":"https://openalex.org/C2775889303","wikidata":"https://www.wikidata.org/wiki/Q17146891","display_name":"Dictyostelium","level":3,"score":0.6460721492767334},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6337587237358093},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.612941324710846},{"id":"https://openalex.org/C2781170229","wikidata":"https://www.wikidata.org/wiki/Q426095","display_name":"Phosphatidylethanolamine","level":5,"score":0.5632198452949524},{"id":"https://openalex.org/C2780495978","wikidata":"https://www.wikidata.org/wiki/Q378789","display_name":"Mycetozoa","level":4,"score":0.5142702460289001},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.5111518502235413},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.5084161162376404},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4379676282405853},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.43559107184410095},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.39582228660583496},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3691844940185547},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.144212007522583},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.1170351505279541},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.058352112770080566},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1099/00221287-121-2-495","doi":"https://doi.org/10.1099/00221287-121-2-495","is_oa":false,"landing_page_url":"https://doi.org/10.1099/00221287-121-2-495","pdf_url":null,"source":{"id":"https://openalex.org/S196799759","display_name":"Microbiology","issn_l":"1350-0872","issn":["1350-0872","1465-2080"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.599.9483","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.599.9483","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://mic.sgmjournals.org/content/121/2/495.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.878.8535","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.878.8535","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.microbiologyresearch.org/docserver/fulltext/micro/121/2/mic-121-2-495.pdf?accname%3Dguest%26checksum%3D3DA86EC484E465D2624FB3F47DE986B3%26expires%3D1460202162%26id%3Did","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7095430854","https://openalex.org/W2603657369","https://openalex.org/W1012468698","https://openalex.org/W1542688083","https://openalex.org/W2155241462","https://openalex.org/W129511646","https://openalex.org/W1972630082","https://openalex.org/W2078916196","https://openalex.org/W2101252152","https://openalex.org/W2060812750"],"abstract_inverted_index":{"A":[0],"cytosolic":[1],"extract":[2],"from":[3],"the":[4,33,37],"cellular":[5],"slime":[6],"mould":[7],"Dictyostelium":[8],"discoideum":[9],"contained":[10],"an":[11],"enzyme":[12],"system":[13],"that":[14],"hydrolysed":[15],"phosphatidylinositol.":[16],"The":[17,27],"route":[18],"of":[19,36],"degradation":[20],"was":[21,29,40],"exclusively":[22],"by":[23,31,44],"deacylation":[24],"to":[25],"glycerophosphoinositol.":[26],"hydrolysis":[28],"inhibited":[30],"phosphatidylethanolamine,":[32],"major":[34],"phospholipid":[35],"organism,":[38],"which":[39],"also":[41],"completely":[42],"deacylated":[43],"myxamoebal":[45],"extracts.":[46]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}