{"id":"https://openalex.org/W2019865494","doi":"https://doi.org/10.1253/circj.cj-14-1303","title":"Association Between Endothelial Function (Assessed on Reactive Hyperemia Peripheral Arterial Tonometry) and Obstructive Sleep Apnea, Visceral Fat Accumulation, and Serum Adiponectin","display_name":"Association Between Endothelial Function (Assessed on Reactive Hyperemia Peripheral Arterial Tonometry) and Obstructive Sleep Apnea, Visceral Fat Accumulation, and Serum Adiponectin","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2019865494","doi":"https://doi.org/10.1253/circj.cj-14-1303","mag":"2019865494","pmid":"https://pubmed.ncbi.nlm.nih.gov/25808226"},"language":"en","primary_location":{"id":"doi:10.1253/circj.cj-14-1303","doi":"https://doi.org/10.1253/circj.cj-14-1303","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-14-1303","pdf_url":"https://www.jstage.jst.go.jp/article/circj/79/6/79_CJ-14-1303/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/circj/79/6/79_CJ-14-1303/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003211399","display_name":"Masanori Azuma","orcid":"https://orcid.org/0009-0008-6049-9161","observed_orcids":["https://orcid.org/0009-0008-6049-9161"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Azuma","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010285205","display_name":"Yuichi Chihara","orcid":"https://orcid.org/0000-0003-0896-283X","observed_orcids":["https://orcid.org/0000-0003-0896-283X"]},"institutions":[{"id":"https://openalex.org/I4210134192","display_name":"Otsu Red Cross Hospital","ror":"https://ror.org/033647p67","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4210134192"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichi Chihara","raw_affiliation_strings":["Department of Respiratory Medicine, Otsu Red Cross Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Otsu Red Cross Hospital","institution_ids":["https://openalex.org/I4210134192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025875009","display_name":"Chikara Yoshimura","orcid":"https://orcid.org/0000-0003-1639-8458","observed_orcids":["https://orcid.org/0000-0003-1639-8458"]},"institutions":[{"id":"https://openalex.org/I4210097767","display_name":"Kyushu University Hospital","ror":"https://ror.org/00ex2fc97","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I135598925","https://openalex.org/I4210097767"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chikara Yoshimura","raw_affiliation_strings":["Sleep Apnea Center, Kyusyu University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep Apnea Center, Kyusyu University Hospital","institution_ids":["https://openalex.org/I4210097767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026990141","display_name":"Kimihiko Murase","orcid":"https://orcid.org/0000-0002-2362-1729","observed_orcids":["https://orcid.org/0000-0002-2362-1729"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kimihiko Murase","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101542463","display_name":"Satoshi Hamada","orcid":"https://orcid.org/0000-0001-7215-9027","observed_orcids":["https://orcid.org/0000-0001-7215-9027"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Hamada","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062454590","display_name":"Ryo Tachikawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryo Tachikawa","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101700258","display_name":"Takeshi Matsumoto","orcid":"https://orcid.org/0000-0002-6546-6376","observed_orcids":["https://orcid.org/0000-0002-6546-6376"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Matsumoto","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089888344","display_name":"Morito Inouchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Morito Inouchi","raw_affiliation_strings":["Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085556486","display_name":"Kiminobu Tanizawa","orcid":"https://orcid.org/0000-0002-5719-0744","observed_orcids":["https://orcid.org/0000-0002-5719-0744"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiminobu Tanizawa","raw_affiliation_strings":["Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061029263","display_name":"Tomohiro Handa","orcid":"https://orcid.org/0000-0002-3378-6412","observed_orcids":["https://orcid.org/0000-0002-3378-6412"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomohiro Handa","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009602385","display_name":"Toru Oga","orcid":"https://orcid.org/0000-0001-7718-8652","observed_orcids":["https://orcid.org/0000-0001-7718-8652"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Oga","raw_affiliation_strings":["Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042756499","display_name":"Michiaki Mishima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michiaki Mishima","raw_affiliation_strings":["Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053180213","display_name":"Kazuo Chin","orcid":"https://orcid.org/0000-0002-1011-7478","observed_orcids":["https://orcid.org/0000-0002-1011-7478"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo Chin","raw_affiliation_strings":["Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6548,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.92609419,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"79","issue":"6","first_page":"1381","last_page":"1389"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.8446999788284302,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.8446999788284302,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0658000037074089,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.05469999834895134,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.8650000095367432},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9819999933242798},{"id":"https://openalex.org/keywords/reactive-hyperemia-index","display_name":"reactive hyperemia index","score":0.8360000252723694},{"id":"https://openalex.org/keywords/peripheral-arterial-tonometry","display_name":"peripheral arterial tonometry","score":0.8790000081062317},{"id":"https://openalex.org/keywords/visceral-obesity","display_name":"visceral obesity","score":0.878000020980835},{"id":"https://openalex.org/keywords/visceral-fat-area","display_name":"visceral fat area","score":0.8870000243186951},{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/apnea-hypopnea-index","display_name":"apnea-hypopnea index","score":0.9089999794960022},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"continuous positive airway pressure","score":0.9520000219345093},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C3019128504","wikidata":"https://www.wikidata.org/wiki/Q948806","display_name":"Reactive hyperemia","level":3,"score":0.9139242768287659},{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.9023790955543518},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8115705251693726},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.7610846161842346},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6959058046340942},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.6501165628433228},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.5898284912109375},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.47992998361587524},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.4368561804294586},{"id":"https://openalex.org/C2776377968","wikidata":"https://www.wikidata.org/wiki/Q618736","display_name":"Apnea\u2013hypopnea index","level":4,"score":0.43369758129119873},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4237346649169922},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4028889536857605},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.37624257802963257},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.3186108469963074},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.09554848074913025},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.08906036615371704}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006940","descriptor_name":"Hyperemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008365","descriptor_name":"Manometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D045422","descriptor_name":"Continuous Positive Airway Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050151","descriptor_name":"Subcutaneous Fat","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D050152","descriptor_name":"Intra-Abdominal Fat","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D052242","descriptor_name":"Adiponectin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D061330","descriptor_name":"Multidetector Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1253/circj.cj-14-1303","doi":"https://doi.org/10.1253/circj.cj-14-1303","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-14-1303","pdf_url":"https://www.jstage.jst.go.jp/article/circj/79/6/79_CJ-14-1303/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},{"id":"pmid:25808226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25808226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation journal : official journal of the Japanese Circulation Society","raw_type":"Journal Article"},{"id":"pmh:oai:repository.kulib.kyoto-u.ac.jp:2433/204577","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2433/204577","pdf_url":null,"source":{"id":"https://openalex.org/S4306401454","display_name":"Kyoto University Research Information Repository (Kyoto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I22299242","host_organization_name":"Kyoto University","host_organization_lineage":["https://openalex.org/I22299242"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"doctoral thesis"}],"best_oa_location":{"id":"doi:10.1253/circj.cj-14-1303","doi":"https://doi.org/10.1253/circj.cj-14-1303","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-14-1303","pdf_url":"https://www.jstage.jst.go.jp/article/circj/79/6/79_CJ-14-1303/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4916295244","display_name":"Establishment of plasma neutrophil gelatinase associated lipocalin level as a biomarker in endothelial dysfunction and renal dysfunction in the early stage in patients with obstructive sleep apnea","funder_award_id":"24621005","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7816500666","display_name":"Relation between systemic and local inflammation and comorbid conditions in sleep apnea","funder_award_id":"26507007","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320326474","display_name":"Teijin Pharma","ror":"https://ror.org/001144c36"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2019865494.pdf","grobid_xml":"https://content.openalex.org/works/W2019865494.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W12554373","https://openalex.org/W39900388","https://openalex.org/W82112906","https://openalex.org/W1523689928","https://openalex.org/W1730924775","https://openalex.org/W1944246003","https://openalex.org/W1965821698","https://openalex.org/W1968895937","https://openalex.org/W1981030840","https://openalex.org/W1984016637","https://openalex.org/W1992748772","https://openalex.org/W1996385661","https://openalex.org/W2009254187","https://openalex.org/W2013704442","https://openalex.org/W2014397752","https://openalex.org/W2019338486","https://openalex.org/W2030611470","https://openalex.org/W2032617616","https://openalex.org/W2036224902","https://openalex.org/W2043595406","https://openalex.org/W2044682081","https://openalex.org/W2044833426","https://openalex.org/W2045096300","https://openalex.org/W2045545124","https://openalex.org/W2050095545","https://openalex.org/W2056667752","https://openalex.org/W2057116025","https://openalex.org/W2059393016","https://openalex.org/W2070633146","https://openalex.org/W2075010492","https://openalex.org/W2080382568","https://openalex.org/W2086225923","https://openalex.org/W2091129932","https://openalex.org/W2103198329","https://openalex.org/W2121622875","https://openalex.org/W2127476409","https://openalex.org/W2128196669","https://openalex.org/W2129989777","https://openalex.org/W2137988289","https://openalex.org/W2142930560","https://openalex.org/W2145899271","https://openalex.org/W2150126194","https://openalex.org/W2160375807","https://openalex.org/W2160921359","https://openalex.org/W2166370133","https://openalex.org/W2171571652","https://openalex.org/W2248492197","https://openalex.org/W2320210054","https://openalex.org/W2884525847","https://openalex.org/W3022302886","https://openalex.org/W4235374500","https://openalex.org/W4236136546","https://openalex.org/W4246370350","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2809275791","https://openalex.org/W3012514207","https://openalex.org/W2050095545","https://openalex.org/W2036836985","https://openalex.org/W2061634012","https://openalex.org/W2625217605","https://openalex.org/W1518546737","https://openalex.org/W1989096607","https://openalex.org/W2129989777","https://openalex.org/W1922547861"],"abstract_inverted_index":{"BACKGROUND:":[0],"Visceral":[1,52],"obesity,":[2],"low":[3],"adiponectin,":[4,167],"and":[5,76,83],"severe":[6,100,110,126],"obstructive":[7],"sleep":[8],"apnea":[9,69],"(OSA)":[10],"are":[11,25],"associated":[12,170],"with":[13,68,90,125,153,171],"cardiovascular":[14],"diseases,":[15],"but":[16,160],"the":[17,97],"interactions":[18],"among":[19],"these":[20],"factors":[21],"on":[22,46],"endothelial":[23,172,180],"dysfunction":[24],"not":[26,161],"well":[27],"known.":[28],"METHODS":[29],"AND":[30],"RESULTS:":[31],"Endothelial":[32],"function":[33,173,181],"in":[34,88,96,123],"133":[35],"patients":[36,89,124],"after":[37,132,147],"polysomnography":[38],"was":[39,54,65,93,129,168,182],"evaluated":[40],"as":[41,56,113],"reactive":[42,47],"hyperemia":[43,48],"index":[44,71],"(RHI)":[45],"peripheral":[49],"arterial":[50],"tonometry.":[51],"obesity":[53,92],"defined":[55],"visceral":[57,73,91,162],"fat":[58,74,163],"area":[59,164],"\u2265100":[60],"cm(2)on":[61],"computed":[62],"tomography.":[63],"RHI":[64,87,119,122],"significantly":[66,94,130],"correlated":[67],"hypopnea":[70],"(AHI),":[72],"area,":[75],"serum":[77,166],"adiponectin":[78],"(r=-0.24,":[79],"P=0.0055,":[80],"r=-0.19,":[81],"P=0.031,":[82],"r=0.20,":[84],"P=0.019,":[85],"respectively).":[86],"decreased":[95],"presence":[98],"of":[99,118,135,187],"OSA":[101,111,127],"(AHI":[102],"\u226530;":[103],"P=0.042).":[104],"On":[105],"multivariate":[106],"regression":[107],"analysis,":[108],"only":[109],"remained":[112],"an":[114],"independent":[115],"predictive":[116],"factor":[117],"(P=0.024,":[120],"R(2)=5.4%).":[121],"(n=44)":[128],"improved":[131],"3":[133,185],"months":[134,186],"continuous":[136],"positive":[137],"airway":[138],"pressure":[139],"(CPAP)":[140],"treatment":[141],"(1.78\u00b10.40":[142],"before":[143],"CPAP":[144,188],"vs.":[145],"2.00\u00b10.53":[146],"CPAP,":[148],"P=0.013),":[149],"similarly":[150],"to":[151,175],"those":[152],"AHI":[154],"<30":[155],"(P=0.45).":[156],"CONCLUSIONS:":[157],"Severe":[158],"OSA,":[159],"or":[165],"independently":[169],"according":[174],"RHI.":[176],"In":[177],"addition,":[178],"impaired":[179],"reversible":[183],"following":[184],"treatment.":[189]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}