{"id":"https://openalex.org/W2019744849","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","title":"Two Forms of Transforming Growth Factor\u2010\u03b2 Are Equally Potent Selective Growth Inhibitors of Early Murine Hematopoiesisab","display_name":"Two Forms of Transforming Growth Factor\u2010\u03b2 Are Equally Potent Selective Growth Inhibitors of Early Murine Hematopoiesisab","publication_year":1990,"publication_date":"1990-06-01","ids":{"openalex":"https://openalex.org/W2019744849","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","mag":"2019744849","pmid":"https://pubmed.ncbi.nlm.nih.gov/2375594"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1990.tb16109.x","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103555411","display_name":"Jonathan R. Keller","orcid":"https://orcid.org/0000-0001-9767-0067","observed_orcids":["https://orcid.org/0000-0001-9767-0067"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"JONATHAN R. KELLER","raw_affiliation_strings":["Biological Carcinogenesis Development Program, Program Resources, Inc., Frederick Cancer Research Facility, Maryland 21701-1013","Biological Carcinogenesis Development Program Program Resources, Inc. Frederick Cancer Research Facility Frederick, Maryland 21701\u20101013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Carcinogenesis Development Program, Program Resources, Inc., Frederick Cancer Research Facility, Maryland 21701-1013","institution_ids":["https://openalex.org/I4210130649"]},{"raw_affiliation_string":"Biological Carcinogenesis Development Program Program Resources, Inc. Frederick Cancer Research Facility Frederick, Maryland 21701\u20101013","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019280595","display_name":"Garwin Kim Sing","orcid":"https://orcid.org/0000-0001-5352-7779","observed_orcids":["https://orcid.org/0000-0001-5352-7779"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"GARWIN K. SING","raw_affiliation_strings":["Laboratory of Molecular Immunoregulation Biological Response Modifiers Program Division of Cancer Treatment National Cancer Institute Frederick Cancer Research Facility Frederick, Maryland 21701-1013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunoregulation Biological Response Modifiers Program Division of Cancer Treatment National Cancer Institute Frederick Cancer Research Facility Frederick, Maryland 21701-1013","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069692025","display_name":"Larry R. Ellingsworth","orcid":"https://orcid.org/0000-0003-3060-8984","observed_orcids":["https://orcid.org/0000-0003-3060-8984"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"LARRY R. ELLINGSWORTH","raw_affiliation_strings":["Collagen Corporation Palo Alto, California 94303"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Corporation Palo Alto, California 94303","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111491871","display_name":"Sandra K. Ruscetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"SANDRA K. RUSCETTI","raw_affiliation_strings":["Laboratory of Genetics National Cancer Institute Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics National Cancer Institute Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112193232","display_name":"Francis W. Ruscetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"FRANCIS W. RUSCETTI","raw_affiliation_strings":["Laboratory of Molecular Immunoregulation Biological Response Modifiers Program Division of Cancer Treatment National Cancer Institute Frederick Cancer Research Facility Frederick, Maryland 21701-1013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunoregulation Biological Response Modifiers Program Division of Cancer Treatment National Cancer Institute Frederick Cancer Research Facility Frederick, Maryland 21701-1013","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103555411"],"corresponding_institution_ids":["https://openalex.org/I4210130649"],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":1.2829,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.79158917,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"593","issue":"1","first_page":"172","last_page":"180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.16089999675750732,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.11180000007152557,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transforming-growth-factor-beta","display_name":"TGF-beta","score":0.9959999918937683},{"id":"https://openalex.org/keywords/tgf-beta-isoforms","display_name":"TGF-beta isoforms","score":0.828000009059906},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.8920000195503235},{"id":"https://openalex.org/keywords/growth-inhibition","display_name":"growth inhibition","score":0.7200000286102295},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.8009999990463257},{"id":"https://openalex.org/keywords/early-hematopoiesis","display_name":"early hematopoiesis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/murine-hematopoiesis","display_name":"murine hematopoiesis","score":0.7620000243186951}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5846100449562073},{"id":"https://openalex.org/C2778489119","wikidata":"https://www.wikidata.org/wiki/Q1962297","display_name":"Reprint","level":2,"score":0.5238828063011169},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.39973750710487366},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3651670217514038},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2830357551574707},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27818763256073},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1814904510974884},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.12680163979530334},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09975674748420715},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003114","descriptor_name":"Colony-Forming Units Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004920","descriptor_name":"Erythropoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006131","descriptor_name":"Growth Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015291","descriptor_name":"Transforming Growth Factors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1990.tb16109.x","doi":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1990.tb16109.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:2375594","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2375594","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7328885630","display_name":null,"funder_award_id":"N01 C0-74102","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W19985982","https://openalex.org/W33813833","https://openalex.org/W110365547","https://openalex.org/W1480727199","https://openalex.org/W1489642554","https://openalex.org/W1495519011","https://openalex.org/W1496494806","https://openalex.org/W1500595986","https://openalex.org/W1524114372","https://openalex.org/W1568406709","https://openalex.org/W1891238929","https://openalex.org/W1921728185","https://openalex.org/W1962774875","https://openalex.org/W1966507279","https://openalex.org/W1973644988","https://openalex.org/W1977037035","https://openalex.org/W1982920370","https://openalex.org/W1994858403","https://openalex.org/W2039186465","https://openalex.org/W2073473087","https://openalex.org/W2087863947","https://openalex.org/W2108104357","https://openalex.org/W2156471525","https://openalex.org/W2417910760","https://openalex.org/W2419668340","https://openalex.org/W4200458652"],"related_works":["https://openalex.org/W2156471525","https://openalex.org/W2080280655","https://openalex.org/W7042493571","https://openalex.org/W2088426194","https://openalex.org/W7096217843","https://openalex.org/W1987383811","https://openalex.org/W19985982","https://openalex.org/W2124210967","https://openalex.org/W2081025616","https://openalex.org/W2419668340"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}