{"id":"https://openalex.org/W2019728980","doi":"https://doi.org/10.1117/12.2039669","title":"Mouse brain imaging using photoacoustic computed tomography","display_name":"Mouse brain imaging using photoacoustic computed tomography","publication_year":2014,"publication_date":"2014-03-03","ids":{"openalex":"https://openalex.org/W2019728980","doi":"https://doi.org/10.1117/12.2039669","mag":"2019728980"},"language":"en","primary_location":{"id":"doi:10.1117/12.2039669","doi":"https://doi.org/10.1117/12.2039669","is_oa":true,"landing_page_url":"https://doi.org/10.1117/12.2039669","pdf_url":"https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8943/894340/Mouse-brain-imaging-using-photoacoustic-computed-tomography/10.1117/12.2039669.pdf","source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8943/894340/Mouse-brain-imaging-using-photoacoustic-computed-tomography/10.1117/12.2039669.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yang Lou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Lou","raw_affiliation_strings":["Washington Univ. in St. Louis (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington Univ. in St. Louis (United States)","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075655523","display_name":"Jun Xia","orcid":"https://orcid.org/0000-0002-9864-7835","observed_orcids":["https://orcid.org/0000-0002-9864-7835"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Xia","raw_affiliation_strings":["Washington Univ. in St. Louis (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington Univ. in St. Louis (United States)","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008233636","display_name":"Lihong V. Wang","orcid":"https://orcid.org/0000-0001-9783-4383","observed_orcids":["https://orcid.org/0000-0001-9783-4383"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lihong V. Wang","raw_affiliation_strings":["Washington Univ. in St. Louis (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington Univ. in St. Louis (United States)","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":1.2948,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.76699883,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"8943","issue":null,"first_page":"894340","last_page":"894340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photoacoustic-computed-tomography","display_name":"photoacoustic computed tomography","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mouse-brain","display_name":"mouse brain","score":0.8149999976158142},{"id":"https://openalex.org/keywords/ex-vivo-brain-imaging","display_name":"ex vivo brain imaging","score":0.8899999856948853},{"id":"https://openalex.org/keywords/acoustic-distortion","display_name":"acoustic distortion","score":0.5889999866485596},{"id":"https://openalex.org/keywords/bone-attenuation","display_name":"bone attenuation","score":0.5979999899864197},{"id":"https://openalex.org/keywords/striatum","display_name":"striatum","score":0.8519999980926514},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":1.0},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.8679999709129333},{"id":"https://openalex.org/keywords/circle-of-willis","display_name":"circle of Willis","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C2779073994","wikidata":"https://www.wikidata.org/wiki/Q1751686","display_name":"Pact","level":2,"score":0.651749312877655},{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.568318247795105},{"id":"https://openalex.org/C126780896","wikidata":"https://www.wikidata.org/wiki/Q899871","display_name":"Distortion (music)","level":4,"score":0.5623642802238464},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.4635879695415497},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4329224228858948},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.432736337184906},{"id":"https://openalex.org/C54932901","wikidata":"https://www.wikidata.org/wiki/Q7187705","display_name":"Photoacoustic imaging in biomedicine","level":2,"score":0.4103752374649048},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.33276697993278503},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.327419638633728},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.32480987906455994},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.32435286045074463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2564551830291748},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23549017310142517},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16145643591880798},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.13233694434165955},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C194257627","wikidata":"https://www.wikidata.org/wiki/Q211554","display_name":"Amplifier","level":3,"score":0.0},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.0},{"id":"https://openalex.org/C2776257435","wikidata":"https://www.wikidata.org/wiki/Q1576430","display_name":"Bandwidth (computing)","level":2,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1117/12.2039669","doi":"https://doi.org/10.1117/12.2039669","is_oa":true,"landing_page_url":"https://doi.org/10.1117/12.2039669","pdf_url":"https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8943/894340/Mouse-brain-imaging-using-photoacoustic-computed-tomography/10.1117/12.2039669.pdf","source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmh:oai:authors.library.caltech.edu:89557","doi":null,"is_oa":false,"landing_page_url":"https://authors.library.caltech.edu/89557/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Book Section"}],"best_oa_location":{"id":"doi:10.1117/12.2039669","doi":"https://doi.org/10.1117/12.2039669","is_oa":true,"landing_page_url":"https://doi.org/10.1117/12.2039669","pdf_url":"https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8943/894340/Mouse-brain-imaging-using-photoacoustic-computed-tomography/10.1117/12.2039669.pdf","source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1721933186","display_name":"Photon tunneling: Shedding new light on biomedicine","funder_award_id":"DP1EB016986","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G6427466625","display_name":"Photoacoustic endoscopy of Barretts esophagus","funder_award_id":"R01CA157277","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7521241259","display_name":"In vivo imaging of single circulating cells","funder_award_id":"R01CA186567","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7834233048","display_name":"Monitoring of Breast Neoadjuvant Therapy by Thermo- and Photo- Acoustic Tomograph","funder_award_id":"R01CA134539","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2019728980.pdf","grobid_xml":"https://content.openalex.org/works/W2019728980.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1967293902","https://openalex.org/W1990608819","https://openalex.org/W1995131110","https://openalex.org/W1999087415","https://openalex.org/W2025406331","https://openalex.org/W2027741125","https://openalex.org/W2090234858","https://openalex.org/W2095648002","https://openalex.org/W2100635475","https://openalex.org/W2166948852","https://openalex.org/W2169735361","https://openalex.org/W4229864936","https://openalex.org/W4252115789"],"related_works":["https://openalex.org/W2009967379","https://openalex.org/W2478901006","https://openalex.org/W2091180557","https://openalex.org/W2669026528","https://openalex.org/W2790860708","https://openalex.org/W3168001243","https://openalex.org/W3171237551","https://openalex.org/W2607720913","https://openalex.org/W2574767055","https://openalex.org/W4401155398"],"abstract_inverted_index":{"Photoacoustic":[0],"computed":[1],"tomography":[2],"(PACT)":[3],"provides":[4],"structural":[5,123],"and":[6,73],"functional":[7],"information":[8],"when":[9],"used":[10],"in":[11,54],"small":[12,58],"animal":[13,59],"brain":[14,26,60,120],"imaging.":[15,61],"Acoustic":[16],"distortion":[17,105],"caused":[18],"by":[19],"bone":[20],"structures":[21,66],"largely":[22],"limits":[23],"the":[24,69,84,90,93,117],"deep":[25],"image":[27,116],"quality.":[28],"In":[29],"our":[30],"work,":[31],"we":[32],"present":[33],"ex":[34],"vivo":[35,55],"PACT":[36,53,111],"images":[37],"of":[38,86,92],"freshly":[39],"excised":[40],"mouse":[41,119],"brain,":[42,94],"intending":[43],"that":[44,65,102],"can":[45,75,95,106],"serve":[46],"as":[47,68],"a":[48],"gold":[49],"standard":[50],"for":[51],"future":[52],"studies":[56],"on":[57],"Our":[62],"results":[63,100],"show":[64],"such":[67],"striatum,":[70],"hippocampus,":[71],"ventricles,":[72],"cerebellum":[74],"be":[76,97,107,113],"clearly":[77],"di":[78],"erentiated.":[79],"An":[80],"artery":[81],"feature":[82],"called":[83],"Circle":[85],"Willis,":[87],"located":[88],"at":[89],"bottom":[91],"also":[96],"seen.":[98],"These":[99],"indicate":[101],"if":[103],"acoustic":[104],"accurately":[108],"accounted":[109],"for,":[110],"should":[112],"able":[114],"to":[115],"entire":[118],"with":[121],"rich":[122],"information.":[124]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}