{"id":"https://openalex.org/W2019679665","doi":"https://doi.org/10.1093/jac/23.4.605","title":"Pharmacokinetics of amoxycillin/clavulanic acid in serum and ascitic fluid in cirrhotic patients","display_name":"Pharmacokinetics of amoxycillin/clavulanic acid in serum and ascitic fluid in cirrhotic patients","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2019679665","doi":"https://doi.org/10.1093/jac/23.4.605","mag":"2019679665","pmid":"https://pubmed.ncbi.nlm.nih.gov/2745264"},"language":"en","primary_location":{"id":"doi:10.1093/jac/23.4.605","doi":"https://doi.org/10.1093/jac/23.4.605","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/23.4.605","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113517593","display_name":"Jean\u2010Didier Grang\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166768","display_name":"H\u00f4pital Tenon","ror":"https://ror.org/05h5v3c50","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166768"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"J. D. Grange","raw_affiliation_strings":["Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France","institution_ids":["https://openalex.org/I4210166768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114254925","display_name":"Alain Gouyette","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A. Gouyette","raw_affiliation_strings":["b Unit\u00e9 de Biochimie-Enzymologie (UA 147 CNRS, U 140 INSERM). Institut Gustave-Roussy Villejuif, Paris, France","Unit\u00e9 de Biochimie-Enzymologie (UA 147 CNRS, U 140 INSERM). Institut Gustave-RoussyVillejuif, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"b Unit\u00e9 de Biochimie-Enzymologie (UA 147 CNRS, U 140 INSERM). Institut Gustave-Roussy Villejuif, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2801843802"]},{"raw_affiliation_string":"Unit\u00e9 de Biochimie-Enzymologie (UA 147 CNRS, U 140 INSERM). Institut Gustave-RoussyVillejuif, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104091867","display_name":"Laurent Gutmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135272","display_name":"H\u00f4pital Paris Saint-Joseph","ror":"https://ror.org/046bx1082","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135272","https://openalex.org/I4405287512"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L. Gutmann","raw_affiliation_strings":["c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","institution_ids":["https://openalex.org/I4210135272"]},{"raw_affiliation_string":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France","institution_ids":["https://openalex.org/I4210135272"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057307093","display_name":"Xavier Amiot","orcid":"https://orcid.org/0000-0002-9912-9888","observed_orcids":["https://orcid.org/0000-0002-9912-9888"]},"institutions":[{"id":"https://openalex.org/I4210135272","display_name":"H\u00f4pital Paris Saint-Joseph","ror":"https://ror.org/046bx1082","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135272","https://openalex.org/I4405287512"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"X. Amiot","raw_affiliation_strings":["c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","institution_ids":["https://openalex.org/I4210135272"]},{"raw_affiliation_string":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France","institution_ids":["https://openalex.org/I4210135272"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018835636","display_name":"Marie-Dominique Kitzis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135272","display_name":"H\u00f4pital Paris Saint-Joseph","ror":"https://ror.org/046bx1082","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135272","https://openalex.org/I4405287512"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M. D. Kitzis","raw_affiliation_strings":["c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","institution_ids":["https://openalex.org/I4210135272"]},{"raw_affiliation_string":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France","institution_ids":["https://openalex.org/I4210135272"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Islam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166768","display_name":"H\u00f4pital Tenon","ror":"https://ror.org/05h5v3c50","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Islam","raw_affiliation_strings":["a Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France","Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pitalTenon, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France","institution_ids":["https://openalex.org/I4210166768"]},{"raw_affiliation_string":"Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pitalTenon, Paris, France","institution_ids":["https://openalex.org/I4210166768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110287448","display_name":"Jacques F. Acar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135272","display_name":"H\u00f4pital Paris Saint-Joseph","ror":"https://ror.org/046bx1082","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135272","https://openalex.org/I4405287512"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. F. Acar","raw_affiliation_strings":["c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"c Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-Joseph Paris, France","institution_ids":["https://openalex.org/I4210135272"]},{"raw_affiliation_string":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Saint-JosephParis, France","institution_ids":["https://openalex.org/I4210135272"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007348302","display_name":"Patrice Jaillon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166768","display_name":"H\u00f4pital Tenon","ror":"https://ror.org/05h5v3c50","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Jaillon","raw_affiliation_strings":["a Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France","Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pitalTenon, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pital Tenon, Paris, France","institution_ids":["https://openalex.org/I4210166768"]},{"raw_affiliation_string":"Service d'h\u00e9patologie et unit\u00e9 de Pharmacologie Clinique, H\u00f4pitalTenon, Paris, France","institution_ids":["https://openalex.org/I4210166768"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5113517593"],"corresponding_institution_ids":["https://openalex.org/I4210166768"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":0.7861,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.66327927,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"23","issue":"4","first_page":"605","last_page":"611"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amoxicillin-clavulanic-acid","display_name":"amoxicillin-clavulanic acid","score":0.9620000123977661},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.9610000252723694},{"id":"https://openalex.org/keywords/ascitic-fluid","display_name":"ascitic fluid","score":0.8420000076293945},{"id":"https://openalex.org/keywords/serum","display_name":"serum","score":0.3959999978542328},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/spontaneous-bacterial-peritonitis","display_name":"spontaneous bacterial peritonitis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/drug-distribution","display_name":"drug distribution","score":0.5910000205039978},{"id":"https://openalex.org/keywords/three-compartment-model","display_name":"three-compartment model","score":0.8809999823570251},{"id":"https://openalex.org/keywords/circulating-half-life","display_name":"serum half-life","score":0.8069999814033508},{"id":"https://openalex.org/keywords/intravenous-administration","display_name":"intravenous administration","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C2779454058","wikidata":"https://www.wikidata.org/wiki/Q415709","display_name":"Clavulanic acid","level":4,"score":0.8431905508041382},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.7664549946784973},{"id":"https://openalex.org/C2992414494","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascitic fluid","level":3,"score":0.7538418769836426},{"id":"https://openalex.org/C2777364826","wikidata":"https://www.wikidata.org/wiki/Q3128789","display_name":"Spontaneous bacterial peritonitis","level":3,"score":0.6307691335678101},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.5704918503761292},{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.5667298436164856},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5497300624847412},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5265583992004395},{"id":"https://openalex.org/C2779708577","wikidata":"https://www.wikidata.org/wiki/Q201928","display_name":"Amoxicillin","level":3,"score":0.4805360436439514},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.44686031341552734},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.43944263458251953},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40848368406295776},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.38331303000450134},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.29733365774154663},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10426107048988342}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000658","descriptor_name":"Amoxicillin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000658","descriptor_name":"Amoxicillin","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D001202","descriptor_name":"Ascitic Fluid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002969","descriptor_name":"Clavulanic Acids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002969","descriptor_name":"Clavulanic Acids","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jac/23.4.605","doi":"https://doi.org/10.1093/jac/23.4.605","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/23.4.605","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:2745264","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2745264","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2083396354","https://openalex.org/W2037706437","https://openalex.org/W2397027316","https://openalex.org/W2410374277","https://openalex.org/W2366543256","https://openalex.org/W2048850213","https://openalex.org/W2082559972","https://openalex.org/W4240908313","https://openalex.org/W2391162822","https://openalex.org/W2037298767"],"abstract_inverted_index":{"A":[0,39],"combination":[1],"of":[2,14,27,35,41,53,81,108],"amoxycillin":[3,56,71,109],"and":[4,32,45,72,112],"clavulanic":[5,60,75,113],"acid":[6,29,114],"(Augmentin)":[7],"might":[8],"be":[9],"useful":[10],"for":[11,70,74],"first-line":[12],"treatment":[13],"spontaneous":[15],"bacterial":[16],"peritonitis":[17],"in":[18,30],"patients":[19],"with":[20],"cirrhosis.":[21],"We":[22],"have":[23],"studied":[24],"the":[25,62,85,104,121,125],"pharmacokinetics":[26],"amoxycillin/clavulanic":[28],"serum":[31,44,65,106],"ascitic":[33,46,86,126],"fluid":[34],"six":[36],"cirrhotic":[37],"patients.":[38],"total":[40],"66":[42],"simultaneous":[43],"samples":[47],"were":[48,93,117],"analysed.":[49],"Following":[50],"iv":[51],"injection":[52],"1":[54],"g":[55,59],"plus":[57],"0.2":[58],"acid,":[61,76],"ascites":[63],"to":[64,95,120],"AUC":[66],"ratio":[67],"was":[68],"1.38":[69],"1.01":[73],"indicating":[77],"a":[78,96],"good":[79],"distribution":[80],"these":[82],"drugs":[83],"into":[84],"fluid.":[87],"In":[88],"this":[89],"study,":[90],"experimental":[91],"data":[92],"fitted":[94],"three":[97],"compartment":[98],"body":[99],"model":[100],"which":[101],"revealed":[102],"that":[103],"prolonged":[105],"half-lives":[107],"(274":[110],"min)":[111,116],"(200":[115],"probably":[118],"due":[119],"slow":[122],"return":[123],"from":[124],"compartment.":[127]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}