{"id":"https://openalex.org/W2019601210","doi":"https://doi.org/10.1530/jrf.0.0730021","title":"Testosterone secretion during gubernacular development and testicular descent in the dog","display_name":"Testosterone secretion during gubernacular development and testicular descent in the dog","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W2019601210","doi":"https://doi.org/10.1530/jrf.0.0730021","mag":"2019601210","pmid":"https://pubmed.ncbi.nlm.nih.gov/3968654"},"language":"en","primary_location":{"id":"doi:10.1530/jrf.0.0730021","doi":"https://doi.org/10.1530/jrf.0.0730021","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730021","pdf_url":"https://rep.bioscientifica.com/downloadpdf/view/journals/rep/73/1/jrf_73_1_003.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rep.bioscientifica.com/downloadpdf/view/journals/rep/73/1/jrf_73_1_003.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053159073","display_name":"Vera Baumans","orcid":"https://orcid.org/0000-0002-9604-1530","observed_orcids":["https://orcid.org/0000-0002-9604-1530"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Vera Baumans","raw_affiliation_strings":["A.I. and Reproduction , State University Utrecht , Yalelaan 1 , 3584 CL Utrecht , The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A.I. and Reproduction , State University Utrecht , Yalelaan 1 , 3584 CL Utrecht , The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108525355","display_name":"S.J. Dieleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S. J. Dieleman","raw_affiliation_strings":["A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036177999","display_name":"H. S. Wouterse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"H. S. Wouterse","raw_affiliation_strings":["Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087312581","display_name":"Leni van Tol","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Leni van Tol","raw_affiliation_strings":["Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031959251","display_name":"Grietje Dijkstra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Grietje Dijkstra","raw_affiliation_strings":["A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108189946","display_name":"CEES J. G. WENSING","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"C. J. G. Wensing","raw_affiliation_strings":["Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","Clinic for Veterinary Obstetrics,","Department of Veterinary Anatomy, State University Utrecht, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Anatomy , State University Utrecht , and Clinic for Veterinary Obstetrics,","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"A.I. and Reproduction, State University Utrecht, Yalelaan 1, 3584 CL Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Clinic for Veterinary Obstetrics,","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Anatomy, State University Utrecht, and","institution_ids":["https://openalex.org/I193662353"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I193662353"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.11309391,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"73","issue":"1","first_page":"21","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.04699999839067459,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone-secretion","display_name":"testosterone secretion","score":0.8889999985694885},{"id":"https://openalex.org/keywords/testicular-descent","display_name":"testicular descent","score":0.9760000109672546},{"id":"https://openalex.org/keywords/dihydrotestosterone","display_name":"dihydrotestosterone","score":0.8870000243186951},{"id":"https://openalex.org/keywords/neonatal-testis","display_name":"neonatal testis","score":0.8420000076293945},{"id":"https://openalex.org/keywords/hcg-stimulation","display_name":"hCG stimulation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/serum-testosterone","display_name":"serum testosterone","score":0.6079999804496765},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.5509999990463257}],"concepts":[{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6774552464485168},{"id":"https://openalex.org/C2776637919","wikidata":"https://www.wikidata.org/wiki/Q624380","display_name":"Descent (aeronautics)","level":2,"score":0.6253339648246765},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.528678834438324},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42793992161750793},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.40865883231163025},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3899625539779663},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38938531279563904},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3821428120136261},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3703007996082306},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.10661786794662476},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002849","descriptor_name":"Chromatography, Gas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006063","descriptor_name":"Chorionic Gonadotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1530/jrf.0.0730021","doi":"https://doi.org/10.1530/jrf.0.0730021","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730021","pdf_url":"https://rep.bioscientifica.com/downloadpdf/view/journals/rep/73/1/jrf_73_1_003.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},{"id":"pmid:3968654","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3968654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of reproduction and fertility","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1530/jrf.0.0730021","doi":"https://doi.org/10.1530/jrf.0.0730021","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730021","pdf_url":"https://rep.bioscientifica.com/downloadpdf/view/journals/rep/73/1/jrf_73_1_003.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2019601210.pdf","grobid_xml":"https://content.openalex.org/works/W2019601210.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W72388677","https://openalex.org/W1963794548","https://openalex.org/W1966492896","https://openalex.org/W1984927708","https://openalex.org/W2086589603","https://openalex.org/W2095353911","https://openalex.org/W2097800507","https://openalex.org/W2113735082","https://openalex.org/W2116789239","https://openalex.org/W2123680932","https://openalex.org/W2134044936","https://openalex.org/W2140028427"],"related_works":["https://openalex.org/W2317415701","https://openalex.org/W2097800507","https://openalex.org/W2140028427","https://openalex.org/W2095353911","https://openalex.org/W2064400526","https://openalex.org/W2153332604","https://openalex.org/W4407210778","https://openalex.org/W2102381725","https://openalex.org/W2432426167","https://openalex.org/W2072029113"],"abstract_inverted_index":{"Serum":[0],"testosterone":[1,63,98,104],"concentrations":[2,105],"ranged":[3],"from":[4],"0.24":[5],"to":[6,40,96],"1.45":[7],"nmol/l":[8],"between":[9],"Day":[10,16,81,86],"53":[11],"post":[12,18],"coitum":[13],"(p.c.)":[14],"until":[15],"40":[17,87],"partum":[19],"(p.p.)":[20],"and":[21,84],"did":[22],"not":[23,58,76],"show":[24],"variations":[25],"that":[26,51],"could":[27,57],"be":[28,41,59],"correlated":[29],"with":[30],"the":[31,66,92],"process":[32],"of":[33,68,91],"testicular":[34],"descent.":[35],"The":[36,61,89],"intratesticular":[37,62],"androgen":[38],"appeared":[39],"mainly":[42],"testosterone,":[43],"its":[44],"concentration":[45,64],"being":[46],"about":[47],"5000-fold":[48],"higher":[49,78],"than":[50,79],"in":[52],"serum":[53,103],"whereas":[54],"5":[55],"alpha-dihydrotestosterone":[56],"demonstrated.":[60],"at":[65,80,85],"initiation":[67],"gubernacular":[69],"regression":[70],"(Day":[71],"0)":[72],"was":[73,99],"apparently,":[74],"but":[75],"significantly,":[77],"49":[82],"p.c.":[83],"p.p.":[88],"ability":[90],"neonatal":[93],"canine":[94],"testis":[95],"synthesize":[97],"indicated":[100],"by":[101],"increased":[102],"after":[106],"hCG":[107],"stimulation.":[108]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}