{"id":"https://openalex.org/W2019535722","doi":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","title":"MEDICAL PROBLEMS IN THE DETERGENT INDUSTRY CAUSED BY PROTEOLYTIC ENZYMES FROM BACILLUS SUBTILIS","display_name":"MEDICAL PROBLEMS IN THE DETERGENT INDUSTRY CAUSED BY PROTEOLYTIC ENZYMES FROM BACILLUS SUBTILIS","publication_year":1972,"publication_date":"1972-01-01","ids":{"openalex":"https://openalex.org/W2019535722","doi":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","mag":"2019535722","pmid":"https://pubmed.ncbi.nlm.nih.gov/4260199"},"language":"en","primary_location":{"id":"doi:10.1111/j.1398-9995.1972.tb01644.x","doi":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","pdf_url":null,"source":{"id":"https://openalex.org/S68090385","display_name":"Allergy","issn_l":"0105-4538","issn":["0105-4538","1398-9995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068233364","display_name":"Carl\u2010J\u00f8han G\u00f6the","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"CARL\u2010JOHAN G\u00d6THE","raw_affiliation_strings":["Department of Occupational Medicine, Karolinska Sjukhuset, Stockholm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational Medicine, Karolinska Sjukhuset, Stockholm","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111017042","display_name":"A Nilz\u00e9n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00c5UKE NILZ\u00c9N","raw_affiliation_strings":["Department of Allergology, Karolinska Sjukhuset, Stockholm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergology, Karolinska Sjukhuset, Stockholm","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110057164","display_name":"Alf Holmgren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"ALF HOLMGREN","raw_affiliation_strings":["Department of Clinical Physiology, Thoracic Clinics, Karolinska Sjukhuset, Stockholm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Physiology, Thoracic Clinics, Karolinska Sjukhuset, Stockholm","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017274317","display_name":"Alfred Szamosi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"ALFRED SZAMOSI","raw_affiliation_strings":["Department of Thoracic Radiology, Karolinska Sjukhuset, Stockholm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Radiology, Karolinska Sjukhuset, Stockholm","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015645094","display_name":"M. Werner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MARGARETA WERNER","raw_affiliation_strings":["Department of Immunology, National Bacteriological Laboratory, Stockholm"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, National Bacteriological Laboratory, Stockholm","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066313081","display_name":"LEIF E. WIDE","orcid":"https://orcid.org/0000-0002-4139-382X","observed_orcids":["https://orcid.org/0000-0002-4139-382X"]},"institutions":[{"id":"https://openalex.org/I1342360035","display_name":"Uppsala University Hospital","ror":"https://ror.org/01apvbh93","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1342360035"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"LEIF WIDE","raw_affiliation_strings":["Department of Clinical Chemistry, Akademiska Sjukhuset, Uppsala"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry, Akademiska Sjukhuset, Uppsala","institution_ids":["https://openalex.org/I1342360035"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068233364"],"corresponding_institution_ids":["https://openalex.org/I1335113835"],"apc_list":{"value":5300,"currency":"USD","value_usd":5300},"apc_paid":null,"fwci":4.6342,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.93877364,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"27","issue":"1","first_page":"63","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.020500000566244125,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacillus-subtilis","display_name":"Bacillus subtilis","score":0.9169999957084656},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.996999979019165},{"id":"https://openalex.org/keywords/detergent-industry","display_name":"detergent industry","score":0.7979999780654907},{"id":"https://openalex.org/keywords/occupational-health","display_name":"occupational health","score":0.5590000152587891},{"id":"https://openalex.org/keywords/skin-inflammation","display_name":"skin inflammation","score":0.5870000123977661},{"id":"https://openalex.org/keywords/skin-irritation","display_name":"skin irritation","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4836357831954956},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.4120924770832062},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3241405487060547},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.10203027725219727}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001412","descriptor_name":"Bacillus subtilis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D002617","descriptor_name":"Chemical Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003902","descriptor_name":"Detergents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004777","descriptor_name":"Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004781","descriptor_name":"Environmental Exposure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004787","descriptor_name":"Environmental Pollution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004796","descriptor_name":"Clinical Enzyme Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009783","descriptor_name":"Dermatitis, Occupational","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009784","descriptor_name":"Occupational Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010447","descriptor_name":"Peptide Hydrolases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D011208","descriptor_name":"Powders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012129","descriptor_name":"Respiratory Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012137","descriptor_name":"Respiratory System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012140","descriptor_name":"Respiratory Tract Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012882","descriptor_name":"Skin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1398-9995.1972.tb01644.x","doi":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1398-9995.1972.tb01644.x","pdf_url":null,"source":{"id":"https://openalex.org/S68090385","display_name":"Allergy","issn_l":"0105-4538","issn":["0105-4538","1398-9995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"journal-article"},{"id":"pmid:4260199","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4260199","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta allergologica","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W246581466","https://openalex.org/W1531774396","https://openalex.org/W1712467530","https://openalex.org/W1964746961","https://openalex.org/W1965614930","https://openalex.org/W1975026685","https://openalex.org/W1986600542","https://openalex.org/W1987300217","https://openalex.org/W1992858288","https://openalex.org/W1997372319","https://openalex.org/W2002740456","https://openalex.org/W2012886135","https://openalex.org/W2013189589","https://openalex.org/W2014898427","https://openalex.org/W2014950129","https://openalex.org/W2017500276","https://openalex.org/W2024123788","https://openalex.org/W2054080856","https://openalex.org/W2064564949","https://openalex.org/W2073271321","https://openalex.org/W2084724473","https://openalex.org/W2104048504","https://openalex.org/W2107052422","https://openalex.org/W2130069702","https://openalex.org/W2222121946","https://openalex.org/W2285458529","https://openalex.org/W2410568292","https://openalex.org/W2427443122","https://openalex.org/W4238481301","https://openalex.org/W4241027971","https://openalex.org/W4255633642"],"related_works":["https://openalex.org/W2418987793","https://openalex.org/W2059006065","https://openalex.org/W2411763315","https://openalex.org/W2058289869","https://openalex.org/W2437686337","https://openalex.org/W4248708619","https://openalex.org/W2427371601","https://openalex.org/W2400350564","https://openalex.org/W2492201303","https://openalex.org/W3135581275"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}