{"id":"https://openalex.org/W2019520645","doi":"https://doi.org/10.1159/000327121","title":"Fine Needle Aspiration of Splenic Extramedullary Hematopoiesis Presenting as a Solitary Mass","display_name":"Fine Needle Aspiration of Splenic Extramedullary Hematopoiesis Presenting as a Solitary Mass","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2019520645","doi":"https://doi.org/10.1159/000327121","mag":"2019520645","pmid":"https://pubmed.ncbi.nlm.nih.gov/12462096"},"language":"en","primary_location":{"id":"doi:10.1159/000327121","doi":"https://doi.org/10.1159/000327121","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000327121","pdf_url":null,"source":{"id":"https://openalex.org/S101987544","display_name":"Acta Cytologica","issn_l":"0001-5547","issn":["0001-5547","1938-2650"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cytologica","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112423855","display_name":"Emma Z. Du","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132395","display_name":"University of California San Diego Medical Center","ror":"https://ror.org/03aw5sn18","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959","https://openalex.org/I4210132395"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emma Du","raw_affiliation_strings":["Department of Pathology, University of California, San Diego Medical Center, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of California, San Diego Medical Center, USA","institution_ids":["https://openalex.org/I4210132395"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006321481","display_name":"Kerith Overstreet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kerith Overstreet","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100640843","display_name":"Wei Zhou","orcid":"https://orcid.org/0000-0001-7049-3283","observed_orcids":["https://orcid.org/0000-0001-7049-3283","https://orcid.org/0000-0002-9936-3789"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Zhou","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010678114","display_name":"Geoffrey Stuart Baird","orcid":"https://orcid.org/0000-0001-9064-6558","observed_orcids":["https://orcid.org/0000-0001-9064-6558"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geoffrey Baird","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063306482","display_name":"Stephen M. Baird","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen Baird","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009960666","display_name":"Michael Bouvet","orcid":"https://orcid.org/0000-0002-0086-2159","observed_orcids":["https://orcid.org/0000-0002-0086-2159"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Bouvet","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110069976","display_name":"Parviz Haghighi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Parviz Haghighi","raw_affiliation_strings":["San Diego Healthcare System"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"San Diego Healthcare System","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0891,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.80811287,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"46","issue":"6","first_page":"1138","last_page":"1142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11267","display_name":"Abdominal Trauma and Injuries","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extramedullary-hematopoiesis","display_name":"extramedullary hematopoiesis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/splenic-mass","display_name":"splenic mass","score":0.7319999933242798},{"id":"https://openalex.org/keywords/fine-needle-aspiration-cytology","display_name":"fine needle aspiration cytology","score":0.949999988079071},{"id":"https://openalex.org/keywords/splenectomy","display_name":"splenectomy","score":0.7919999957084656},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.5550000071525574},{"id":"https://openalex.org/keywords/hematopoietic-precursor-cells","display_name":"hematopoietic precursors","score":0.7710000276565552},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.574999988079071},{"id":"https://openalex.org/keywords/asymptomatic-patients","display_name":"asymptomatic patients","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C2778080410","wikidata":"https://www.wikidata.org/wiki/Q5422215","display_name":"Extramedullary hematopoiesis","level":4,"score":0.9696303606033325},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8742384314537048},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.6144457459449768},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.5556443333625793},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5412459373474121},{"id":"https://openalex.org/C2779060813","wikidata":"https://www.wikidata.org/wiki/Q17143415","display_name":"Hematopathology","level":5,"score":0.514251172542572},{"id":"https://openalex.org/C2776309230","wikidata":"https://www.wikidata.org/wiki/Q580383","display_name":"Splenectomy","level":3,"score":0.5007307529449463},{"id":"https://openalex.org/C2776170712","wikidata":"https://www.wikidata.org/wiki/Q180071","display_name":"Fine-needle aspiration","level":3,"score":0.43620288372039795},{"id":"https://openalex.org/C2778654104","wikidata":"https://www.wikidata.org/wiki/Q1881849","display_name":"Cytopathology","level":3,"score":0.4353763163089752},{"id":"https://openalex.org/C2780076729","wikidata":"https://www.wikidata.org/wiki/Q1752571","display_name":"Myelofibrosis","level":3,"score":0.42893150448799133},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.4171268045902252},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.24922144412994385},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.21475204825401306},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.20751458406448364},{"id":"https://openalex.org/C18823058","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cytology","level":2,"score":0.1344742476940155},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10475316643714905},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C174475383","wikidata":"https://www.wikidata.org/wiki/Q246128","display_name":"Cytogenetics","level":4,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001707","descriptor_name":"Biopsy, Needle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006411","descriptor_name":"Hematopoiesis, Extramedullary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013160","descriptor_name":"Splenic Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013160","descriptor_name":"Splenic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1159/000327121","doi":"https://doi.org/10.1159/000327121","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000327121","pdf_url":null,"source":{"id":"https://openalex.org/S101987544","display_name":"Acta Cytologica","issn_l":"0001-5547","issn":["0001-5547","1938-2650"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cytologica","raw_type":"journal-article"},{"id":"pmid:12462096","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12462096","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta cytologica","raw_type":"Case Reports"},{"id":"pmh:oai:bibmed.ucla.edu.ve:T070000059054/19","doi":null,"is_oa":false,"landing_page_url":"http://bibmed.ucla.edu.ve/cgi-win/be_alex.exe?Acceso=T070000059054/19&Nombrebd=bmucla","pdf_url":null,"source":{"id":"https://openalex.org/S7407064131","display_name":"UCLA - Biblioteca de Ciencias de la Salud","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I19325673","host_organization_name":"Universidad Centroccidental Lisandro Alvarado","host_organization_lineage":["https://openalex.org/I19325673"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W108038265","https://openalex.org/W1969315214","https://openalex.org/W1987210905","https://openalex.org/W1992480916","https://openalex.org/W2007567046","https://openalex.org/W2028428877","https://openalex.org/W2074231272","https://openalex.org/W2147556765","https://openalex.org/W2418459589"],"related_works":["https://openalex.org/W6991006184","https://openalex.org/W1933876307","https://openalex.org/W2078730863","https://openalex.org/W2046700678","https://openalex.org/W2409574975","https://openalex.org/W2413195990","https://openalex.org/W7074132772","https://openalex.org/W2259038492","https://openalex.org/W2121303198","https://openalex.org/W2401684034"],"abstract_inverted_index":{"BACKGROUND:":[0],"Extramedullary":[1],"hematopoiesis":[2,12],"(EMH)":[3],"generally":[4],"occurs":[5],"in":[6,28,71,82,101,143,163,173,181,199,215,224],"patients":[7,50,225],"with":[8,104],"deficient":[9],"bone":[10],"marrow":[11,21],"secondary":[13],"to":[14,161],"either":[15,132],"peripheral":[16],"red":[17],"cell":[18],"destruction":[19],"or":[20,134],"replacement.":[22],"EMH":[23,38,87,142,159,212],"is":[24,59,152,169],"most":[25],"commonly":[26],"seen":[27],"the":[29,56,64,68,75,125,153,174,182,195,200,216],"liver":[30],"and":[31],"spleen":[32],"as":[33,40,89],"a":[34,41,45,90,102,105,113,170],"diffuse":[35],"lesion.":[36],"Rarely":[37],"presents":[39],"solitary":[42,157],"mass,":[43,95],"posing":[44],"diagnostic":[46],"dilemma.":[47],"In":[48,122,205],"asymptomatic":[49,165],"without":[51,226],"obvious":[52,227],"evidence":[53,130],"of":[54,77,107,115,127,131,141,156,176,184,197,202,219],"hematopathology,":[55],"differential":[57,217],"diagnosis":[58,114,183,218],"even":[60,223],"more":[61],"complex.":[62],"Despite":[63],"several":[65],"articles":[66],"detailing":[67],"radiographic":[69],"findings":[70,111],"EMH,":[72,116,128,185],"fewer":[73],"promote":[74],"utility":[76],"fine":[78],"needle":[79],"aspiration":[80],"(FNA)":[81],"making":[83],"this":[84,144,151],"diagnosis.":[85],"CASE:":[86],"presented":[88],"discrete,":[91],"6-cm,":[92],"tumorlike":[93],"splenic":[94,158,178,203,221],"first":[96,154],"identified":[97,191],"on":[98],"computed":[99],"tomography":[100],"patient":[103,145],"history":[106],"prostate":[108],"carcinoma.":[109],"FNA":[110,168,198],"suggested":[112],"which":[117],"was":[118,137],"confirmed":[119],"by":[120],"splenectomy.":[121],"searching":[123],"for":[124],"cause":[126,140],"no":[129],"metastatic":[133],"hematologic":[135,228],"disease":[136],"identified.":[138],"The":[139],"remains":[146],"unknown.":[147],"To":[148],"our":[149,207],"knowledge,":[150],"case":[155,208],"reported":[160],"occur":[162],"an":[164],"patient.":[166],"CONCLUSION:":[167],"useful":[171],"adjunct":[172],"evaluation":[175],"isolated":[177,220],"masses,":[179],"particularly":[180],"where":[186],"hematopoietic":[187],"precursors":[188],"are":[189],"readily":[190],"cytologically.":[192],"We":[193],"advocate":[194],"use":[196],"management":[201],"masses.":[204],"addition,":[206],"also":[209],"suggests":[210],"that":[211],"be":[213],"included":[214],"lesions,":[222],"disorders.":[229]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}